CA2937432A1 - Kits-of-parts comprising nucleic acids able to form a kissing complex and their uses thereof - Google Patents
Kits-of-parts comprising nucleic acids able to form a kissing complex and their uses thereof Download PDFInfo
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- CA2937432A1 CA2937432A1 CA2937432A CA2937432A CA2937432A1 CA 2937432 A1 CA2937432 A1 CA 2937432A1 CA 2937432 A CA2937432 A CA 2937432A CA 2937432 A CA2937432 A CA 2937432A CA 2937432 A1 CA2937432 A1 CA 2937432A1
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- Prior art keywords
- nucleic acid
- molecule
- kit
- acid molecule
- sequence
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/531—Stem-loop; Hairpin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13306546.6 | 2013-11-13 | ||
| EP13306546 | 2013-11-13 | ||
| PCT/EP2014/074548 WO2015071385A2 (en) | 2013-11-13 | 2014-11-13 | Kits-of-parts comprising nucleic acids able to form a kissing complex and their uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2937432A1 true CA2937432A1 (en) | 2015-05-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2937432A Abandoned CA2937432A1 (en) | 2013-11-13 | 2014-11-13 | Kits-of-parts comprising nucleic acids able to form a kissing complex and their uses thereof |
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| Country | Link |
|---|---|
| US (1) | US20160274095A1 (https=) |
| EP (1) | EP3068882A2 (https=) |
| JP (1) | JP2016539639A (https=) |
| CA (1) | CA2937432A1 (https=) |
| WO (1) | WO2015071385A2 (https=) |
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| US9963706B2 (en) * | 2015-03-09 | 2018-05-08 | Base Pair Biotechnologies, Inc. | Methods and compositions for backscattering interferometry |
| US11905559B2 (en) | 2016-08-17 | 2024-02-20 | Maumita Mandal | Materials and methods for controlling gene expression |
| WO2023137559A1 (en) * | 2022-01-21 | 2023-07-27 | Neoventures Biotechnology Inc. | A method for reproducible aptamer selection using closed sequence solution spaces |
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| US4868103A (en) | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
| IE66597B1 (en) | 1989-05-10 | 1996-01-24 | Akzo Nv | Method for the synthesis of ribonucleic acid (RNA) |
| US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US5270163A (en) | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
| US5580737A (en) | 1990-06-11 | 1996-12-03 | Nexstar Pharmaceuticals, Inc. | High-affinity nucleic acid ligands that discriminate between theophylline and caffeine |
| EP0786469B1 (en) | 1990-06-11 | 2006-03-01 | Gilead Sciences, Inc. | Methods of use of nucleic acid ligands |
| DE4123673A1 (de) | 1991-07-17 | 1993-01-21 | Leybold Durferrit Gmbh | Vorrichtung zum schalten einer hochstromzufuehrung |
| DE69326967T2 (de) | 1992-01-17 | 2000-06-15 | Lakowicz, Joseph R. | Phasenmodulationsenergieübertragungsfluoroimmunassay |
| US6469158B1 (en) | 1992-05-14 | 2002-10-22 | Ribozyme Pharmaceuticals, Incorporated | Synthesis, deprotection, analysis and purification of RNA and ribozymes |
| US6787305B1 (en) | 1998-03-13 | 2004-09-07 | Invitrogen Corporation | Compositions and methods for enhanced synthesis of nucleic acid molecules |
| US20020161219A1 (en) | 2001-02-21 | 2002-10-31 | Anastassia Kanavarioti | Non-enzymatic large scale synthesis of RNA |
| US20050037394A1 (en) | 2002-12-03 | 2005-02-17 | Keefe Anthony D. | Method for in vitro selection of 2'-substituted nucleic acids |
| JP2008512097A (ja) | 2004-09-07 | 2008-04-24 | アーケミックス コーポレイション | アプタマー医薬品化学 |
| WO2008039254A2 (en) * | 2006-06-02 | 2008-04-03 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rna nanoparticles and nanotubes |
| WO2010148085A1 (en) * | 2009-06-16 | 2010-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rna nanoparticles and methods of use |
| US9297013B2 (en) * | 2011-06-08 | 2016-03-29 | University Of Cincinnati | pRNA multivalent junction domain for use in stable multivalent RNA nanoparticles |
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- 2014-11-13 EP EP14799399.2A patent/EP3068882A2/en not_active Withdrawn
- 2014-11-13 JP JP2016531034A patent/JP2016539639A/ja active Pending
- 2014-11-13 WO PCT/EP2014/074548 patent/WO2015071385A2/en not_active Ceased
- 2014-11-13 US US15/036,558 patent/US20160274095A1/en not_active Abandoned
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| WO2015071385A2 (en) | 2015-05-21 |
| WO2015071385A3 (en) | 2015-07-09 |
| EP3068882A2 (en) | 2016-09-21 |
| US20160274095A1 (en) | 2016-09-22 |
| JP2016539639A (ja) | 2016-12-22 |
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