CA2937417A1 - Procede ameliore pour la preparation de trazodone et son sel de chlorhydrate - Google Patents

Procede ameliore pour la preparation de trazodone et son sel de chlorhydrate Download PDF

Info

Publication number
CA2937417A1
CA2937417A1 CA2937417A CA2937417A CA2937417A1 CA 2937417 A1 CA2937417 A1 CA 2937417A1 CA 2937417 A CA2937417 A CA 2937417A CA 2937417 A CA2937417 A CA 2937417A CA 2937417 A1 CA2937417 A1 CA 2937417A1
Authority
CA
Canada
Prior art keywords
compound
trazodone
free base
chloride
tetra
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2937417A
Other languages
English (en)
Other versions
CA2937417C (fr
Inventor
Shashikant KADAM
Narender Rao SOMISETTI
Srinivas ASHILI
Narsimulu RAIGONI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Piramal Pharma Ltd
Original Assignee
Piramal Enterprises Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Piramal Enterprises Ltd filed Critical Piramal Enterprises Ltd
Publication of CA2937417A1 publication Critical patent/CA2937417A1/fr
Application granted granted Critical
Publication of CA2937417C publication Critical patent/CA2937417C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA2937417A 2014-01-21 2014-12-12 Procede ameliore pour la preparation de trazodone et son sel de chlorhydrate Active CA2937417C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN203/MUM/2014 2014-01-21
IN203MU2014 IN2014MU00203A (fr) 2014-01-21 2014-12-12
PCT/IB2014/066841 WO2015110883A1 (fr) 2014-01-21 2014-12-12 Procédé amélioré pour la préparation de trazodone et son sel de chlorhydrate

Publications (2)

Publication Number Publication Date
CA2937417A1 true CA2937417A1 (fr) 2015-07-30
CA2937417C CA2937417C (fr) 2022-04-12

Family

ID=53680891

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2937417A Active CA2937417C (fr) 2014-01-21 2014-12-12 Procede ameliore pour la preparation de trazodone et son sel de chlorhydrate

Country Status (6)

Country Link
EP (1) EP3097099A4 (fr)
JP (1) JP2017505302A (fr)
CA (1) CA2937417C (fr)
IL (1) IL246835A0 (fr)
IN (1) IN2014MU00203A (fr)
WO (1) WO2015110883A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL234822B1 (pl) 2017-03-14 2020-04-30 Politechnika Krakowska Im Tadeusza Kosciuszki Sposób otrzymywania trazodonu
CN117517545A (zh) * 2023-12-08 2024-02-06 重庆锐恩医药有限公司 一种盐酸曲唑酮有关物质检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
US4252806A (en) * 1979-09-24 1981-02-24 Mead Johnson & Company Triazoloquinolones
HU201324B (en) * 1988-07-29 1990-10-28 Egyt Gyogyszervegyeszeti Gyar New process for production of substituated 1,2,4-triasole (4,3-a)-piridin-2 (2h)-on
ITMI20071603A1 (it) * 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata
US20090209550A1 (en) * 2008-02-20 2009-08-20 Auspex Pharmaceuticals, Inc. Substituted triazolopyridines

Also Published As

Publication number Publication date
CA2937417C (fr) 2022-04-12
IL246835A0 (en) 2016-08-31
EP3097099A1 (fr) 2016-11-30
JP2017505302A (ja) 2017-02-16
IN2014MU00203A (fr) 2015-09-25
WO2015110883A1 (fr) 2015-07-30
EP3097099A4 (fr) 2017-08-23

Similar Documents

Publication Publication Date Title
CA2751498C (fr) Purification de 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine
TWI513691B (zh) 製備苯并咪唑衍生物之方法
JP6441478B2 (ja) 2置換1,4−ベンゼンジアミン及びその塩を調製する方法
US10836730B2 (en) Process for preparation and purification of vortioxetine hydrobromide
JP2008502707A (ja) クエチアピンフマレートの調製方法
US20180237390A1 (en) Improved process for the preparation of apremilast
TW200940525A (en) Process for the preparation of 6-substituted-1-(2H)-isoquinolinones
CA2937417C (fr) Procede ameliore pour la preparation de trazodone et son sel de chlorhydrate
EP2608791B1 (fr) Procédé pour la préparation d'imatinib base
US7737302B2 (en) Process for preparing bupropion hydrochloride
CA2837251A1 (fr) Procede pour la preparation de paliperidone
US20100063299A1 (en) Process for Preparing Irbesartan
US8049007B2 (en) Preparation of amorolfine
US9045456B2 (en) Method for producing imatinib base
JP6242298B2 (ja) 1−(3−ベンゾイルオキシプロピル)−7−シアノ−5−[(2r)−2−({2−[2−(2,2,2−トリフルオロエトキシ)フェノキシ]エチル}アミノ)プロピル]インドリンまたはその塩を製造する方法
US10196400B2 (en) Process for the preparation of lurasidone and its intermediate
SK134899A3 (en) Process for preparing o-(3-amino-2-hydroxy-propyl)hydroxymic acid halides
WO2015155704A1 (fr) Procédé amélioré de préparation du monohydrate du dichlorhydrate de pramipexole
CA2433720A1 (fr) Procede ameliore permettant la preparation de chlorhydrate dihydrate d'ondansetron
US11161821B2 (en) Process for the preparation of Eltrombopag olamine and its intermediates
JP7049371B2 (ja) 置換4-アミノインダン誘導体を調製する方法
JP2009529062A (ja) フマル酸クエチアピンを調製するための改良法
JP5917514B2 (ja) アルキルアニリンの選択的なメタ位クロル化の方法
JP2009280554A (ja) ベンゾオキサジアゾール化合物の製造法
WO2013002253A1 (fr) Procédé de préparation d'un dérivé de benzophénone

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20191206