CA2934012A1 - Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel - Google Patents

Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel Download PDF

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Publication number
CA2934012A1
CA2934012A1 CA2934012A CA2934012A CA2934012A1 CA 2934012 A1 CA2934012 A1 CA 2934012A1 CA 2934012 A CA2934012 A CA 2934012A CA 2934012 A CA2934012 A CA 2934012A CA 2934012 A1 CA2934012 A1 CA 2934012A1
Authority
CA
Canada
Prior art keywords
sphingomyelin
sample
biomarkers
plasma
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2934012A
Other languages
English (en)
French (fr)
Inventor
Beate Kamlage
Regina Reszka
Erik Peter
Jurgen Kastler
Philipp Schatz
Holger Kalthoff
Bodo Schniewind
Julia Mayerle
Markus Lerch
Christian Pilarsky
Robert Grutzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metanomics Health GmbH
Original Assignee
Metanomics Health GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metanomics Health GmbH filed Critical Metanomics Health GmbH
Publication of CA2934012A1 publication Critical patent/CA2934012A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00Assays, e.g. immunoassays or enzyme assays, involving lipids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04Phospholipids, i.e. phosphoglycerides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/08Sphingolipids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Ecology (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Gastroenterology & Hepatology (AREA)
CA2934012A 2013-12-20 2014-12-19 Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel Abandoned CA2934012A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13198959 2013-12-20
EP13198959.2 2013-12-20
PCT/EP2014/078765 WO2015091962A1 (en) 2013-12-20 2014-12-19 Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel

Publications (1)

Publication Number Publication Date
CA2934012A1 true CA2934012A1 (en) 2015-06-25

Family

ID=49885030

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2934012A Abandoned CA2934012A1 (en) 2013-12-20 2014-12-19 Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel

Country Status (7)

Country Link
US (1) US10168333B2 (https=)
EP (2) EP3431998A1 (https=)
JP (1) JP2017504011A (https=)
AU (1) AU2014368412A1 (https=)
CA (1) CA2934012A1 (https=)
ES (1) ES2698374T3 (https=)
WO (1) WO2015091962A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180217125A1 (en) * 2014-03-26 2018-08-02 Metanomics Health Means and methods for the determination of the quality of blood samples based on a metabolite panel
EP3314264A1 (en) * 2015-06-25 2018-05-02 Metanomics Health GmbH Means and methods for diagnosing pancreatic cancer in a subject based on a biomarker panel
JP2017067510A (ja) * 2015-09-29 2017-04-06 花王株式会社 脂質の質量分析方法
KR101937531B1 (ko) 2016-09-28 2019-01-10 국립암센터 대장암 진단 장치와 대장암 진단 정보 제공 방법
KR102549063B1 (ko) * 2016-12-15 2023-06-28 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 췌관 선암종의 검출 및 치료를 위한 방법
WO2018143336A1 (ja) * 2017-02-03 2018-08-09 住友化学株式会社 膵臓癌の検査方法
EP3502699A1 (en) * 2017-12-20 2019-06-26 Metanomics Health GmbH Methods for diagnosing pancreatic cancer
EP3806719B1 (en) * 2018-06-14 2025-08-20 Metabolomycs, Inc. Metabolomic signatures for diagnosing and prognosing ovarian cancer
CN109288827B (zh) * 2018-09-29 2020-05-26 桂林医学院附属医院 神经酰胺酶抑制剂D-e-MAPP在制备改善急性胰腺炎的药物中的应用
ES2799973A1 (es) * 2019-06-19 2020-12-22 Univ Granada Panel de metabolitos como biomarcadores para el diagnostico de cancer de pancreas
WO2022140380A1 (en) * 2020-12-21 2022-06-30 Pancreomics Llc Metabolomic signatures for predicting, diagnosing, and prognosing chronic pancreatitis
WO2024059549A2 (en) * 2022-09-12 2024-03-21 Board Of Regents, The University Of Texas System Methods for the detection and treatment of pancreatic ductal adenocarcinoma
TWI859033B (zh) 2023-12-18 2024-10-11 安益藥業股份有限公司 一種診斷犬科動物胰臟炎的方法與試劑組與一種使用醯基肉鹼作為診斷犬科動物胰臟炎之用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540884A (en) 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
US5397894A (en) 1993-05-28 1995-03-14 Varian Associates, Inc. Method of high mass resolution scanning of an ion trap mass spectrometer
JP2005526962A (ja) 2002-02-28 2005-09-08 メタノミクス ゲーエムベーハー ウント ツェーオー.カーゲーアーアー 物質の混合物を分析する質量分析方法
SG10201405975VA (en) * 2009-10-01 2014-11-27 Phenomenome Discoveries Inc Serum-based biomarkers of pancreatic cancer and uses thereof for diseasedetection and diagnosis
EP2415877A3 (en) * 2010-02-17 2012-02-15 Deutsches Krebsforschungszentrum Means and methods for diagnosing pancreatic cancer
EP3355057A3 (en) 2010-06-01 2018-12-12 Metanomics Health GmbH Means and methods for diagnosing pancreatic cancer in a subject
ES2638522T3 (es) * 2010-06-23 2017-10-23 University Of Louisville Research Foundation, Inc. Procedimientos para detectar cáncer
CA2857401A1 (en) 2011-11-30 2013-06-06 Metanomics Health Gmbh Device and methods to diagnose pancreatic cancer
CN104395758A (zh) 2012-05-18 2015-03-04 日东纺绩株式会社 用于检测胰腺癌的标志物

Also Published As

Publication number Publication date
JP2017504011A (ja) 2017-02-02
EP3431998A1 (en) 2019-01-23
WO2015091962A1 (en) 2015-06-25
AU2014368412A1 (en) 2016-07-07
EP3084443B1 (en) 2018-08-22
US20160313338A1 (en) 2016-10-27
ES2698374T3 (es) 2019-02-04
EP3084443A1 (en) 2016-10-26
US10168333B2 (en) 2019-01-01

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20210309