CA2932127C - Compositions and methods for reducing major adverse cardiovascular events - Google Patents

Compositions and methods for reducing major adverse cardiovascular events Download PDF

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Publication number
CA2932127C
CA2932127C CA2932127A CA2932127A CA2932127C CA 2932127 C CA2932127 C CA 2932127C CA 2932127 A CA2932127 A CA 2932127A CA 2932127 A CA2932127 A CA 2932127A CA 2932127 C CA2932127 C CA 2932127C
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subject
pharmaceutically acceptable
sustained release
acceptable salt
administration
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CA2932127A
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English (en)
French (fr)
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CA2932127A1 (en
Inventor
Preston KLASSEN
Kristin Taylor
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Nalpropion Pharmaceuticals LLC
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Nalpropion Pharmaceuticals LLC
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Publication of CA2932127A1 publication Critical patent/CA2932127A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CA2932127A 2013-12-06 2014-12-04 Compositions and methods for reducing major adverse cardiovascular events Active CA2932127C (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201361913216P 2013-12-06 2013-12-06
US61/913,216 2013-12-06
US201361914938P 2013-12-11 2013-12-11
US61/914,938 2013-12-11
US201461984580P 2014-04-25 2014-04-25
US61/984,580 2014-04-25
US14/322,810 US8969371B1 (en) 2013-12-06 2014-07-02 Compositions and methods for weight loss in at risk patient populations
US14/322,810 2014-07-02
PCT/US2014/068527 WO2015085044A1 (en) 2013-12-06 2014-12-04 Compositions and methods for reducing major adverse cardiovascular events

Publications (2)

Publication Number Publication Date
CA2932127A1 CA2932127A1 (en) 2015-06-11
CA2932127C true CA2932127C (en) 2023-05-02

Family

ID=52575014

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2932127A Active CA2932127C (en) 2013-12-06 2014-12-04 Compositions and methods for reducing major adverse cardiovascular events

Country Status (33)

Country Link
US (9) US8969371B1 (OSRAM)
EP (2) EP3076971B1 (OSRAM)
JP (2) JP6665094B2 (OSRAM)
KR (3) KR20230152800A (OSRAM)
CN (3) CN114404419A (OSRAM)
AU (1) AU2014360492A1 (OSRAM)
BR (1) BR112016012755A2 (OSRAM)
CA (1) CA2932127C (OSRAM)
CL (1) CL2016001362A1 (OSRAM)
CR (1) CR20160313A (OSRAM)
CY (1) CY1125114T1 (OSRAM)
DK (1) DK3076971T3 (OSRAM)
EA (1) EA201690964A1 (OSRAM)
EC (1) ECSP16057765A (OSRAM)
ES (1) ES2903391T3 (OSRAM)
HR (1) HRP20220058T1 (OSRAM)
HU (1) HUE057551T2 (OSRAM)
IL (3) IL300870A (OSRAM)
JO (1) JOP20140344B1 (OSRAM)
LT (1) LT3076971T (OSRAM)
MX (2) MX389742B (OSRAM)
PE (1) PE20161034A1 (OSRAM)
PL (1) PL3076971T3 (OSRAM)
PT (1) PT3076971T (OSRAM)
RS (1) RS62846B1 (OSRAM)
RU (1) RU2711638C2 (OSRAM)
SG (1) SG10201808055QA (OSRAM)
SI (1) SI3076971T1 (OSRAM)
TN (1) TN2016000231A1 (OSRAM)
TW (1) TWI661826B (OSRAM)
UY (1) UY35864A (OSRAM)
WO (1) WO2015085044A1 (OSRAM)
ZA (1) ZA201603831B (OSRAM)

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US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
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US20110144145A1 (en) 2008-05-30 2011-06-16 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
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KR20220042241A (ko) * 2012-06-06 2022-04-04 오렉시젠 세러퓨틱스 인크. 과체중 및 비만의 치료 방법
US8969371B1 (en) 2013-12-06 2015-03-03 Orexigen Therapeutics, Inc. Compositions and methods for weight loss in at risk patient populations
US9968659B2 (en) 2016-03-04 2018-05-15 Novo Nordisk A/S Liraglutide in cardiovascular conditions
EP3493574B1 (en) * 2016-08-11 2023-04-12 Huawei Technologies Co., Ltd. Wireless communication method based on unlicensed frequency spectrum, and base station and terminal device
US20250332152A1 (en) * 2021-12-09 2025-10-30 Incarda Therapeutics, Inc. Inhaled therapy for cardiac arrhythmia
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

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Publication number Publication date
PT3076971T (pt) 2022-01-26
RS62846B1 (sr) 2022-02-28
JP2020037593A (ja) 2020-03-12
TW201607536A (zh) 2016-03-01
US9119850B2 (en) 2015-09-01
IL300870A (en) 2023-04-01
US10231964B2 (en) 2019-03-19
US20150366860A1 (en) 2015-12-24
AU2014360492A1 (en) 2016-06-23
SG10201808055QA (en) 2018-10-30
US10231962B2 (en) 2019-03-19
KR20160095076A (ko) 2016-08-10
US10835527B2 (en) 2020-11-17
US20150182524A1 (en) 2015-07-02
PL3076971T3 (pl) 2022-04-04
EP3076971B1 (en) 2021-10-20
JOP20140344B1 (ar) 2021-08-17
SI3076971T1 (sl) 2022-04-29
CN114404419A (zh) 2022-04-29
US20180243288A1 (en) 2018-08-30
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