CA2930042C - Prrs virus variant, european prrs virus cdna clone, and uses thereof - Google Patents
Prrs virus variant, european prrs virus cdna clone, and uses thereof Download PDFInfo
- Publication number
- CA2930042C CA2930042C CA2930042A CA2930042A CA2930042C CA 2930042 C CA2930042 C CA 2930042C CA 2930042 A CA2930042 A CA 2930042A CA 2930042 A CA2930042 A CA 2930042A CA 2930042 C CA2930042 C CA 2930042C
- Authority
- CA
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- Prior art keywords
- virus
- nucleic acid
- seq
- sequence
- prrs
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10041—Use of virus, viral particle or viral elements as a vector
- C12N2770/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Analytical Chemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13199177.0 | 2013-12-20 | ||
| EP13199177 | 2013-12-20 | ||
| EP14175691.6 | 2014-07-03 | ||
| EP14175691 | 2014-07-03 | ||
| PCT/EP2014/078929 WO2015092058A1 (en) | 2013-12-20 | 2014-12-19 | Prrs virus variant, european prrs virus cdna clone, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2930042A1 CA2930042A1 (en) | 2015-06-25 |
| CA2930042C true CA2930042C (en) | 2022-06-21 |
Family
ID=52347295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2930042A Active CA2930042C (en) | 2013-12-20 | 2014-12-19 | Prrs virus variant, european prrs virus cdna clone, and uses thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10010601B2 (enExample) |
| EP (2) | EP3083947B1 (enExample) |
| JP (3) | JP6886291B2 (enExample) |
| KR (2) | KR102270344B1 (enExample) |
| CN (1) | CN105829528B (enExample) |
| AU (2) | AU2014369774B2 (enExample) |
| CA (1) | CA2930042C (enExample) |
| DK (2) | DK3591042T5 (enExample) |
| EA (1) | EA039060B1 (enExample) |
| ES (2) | ES2940691T3 (enExample) |
| HU (1) | HUE061768T2 (enExample) |
| MX (2) | MX2020010248A (enExample) |
| WO (1) | WO2015092058A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012217170B2 (en) | 2011-02-17 | 2016-07-28 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of PRRSV |
| WO2012110489A2 (en) | 2011-02-17 | 2012-08-23 | Boehringer Ingelheim Vetmedica Gmbh | Novel european prrsv strain |
| AU2014369774B2 (en) | 2013-12-20 | 2020-11-26 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus variant, European PRRS virus cDNA clone, and uses thereof |
| MX393666B (es) | 2016-08-05 | 2025-03-24 | Hipra Scient S L U | CLON DE ADNc DEL VIRUS DEL SÍNDROME REPRODUCTIVO Y RESPIRATORIO PORCINO Y USOS DEL MISMO. |
| WO2020138761A1 (ko) * | 2018-12-27 | 2020-07-02 | 주식회사 바이오포아 | 돼지 생식기 및 호흡기 증후군 바이러스의 키메라 바이러스 및 이를 이용한 백신 |
| KR102335864B1 (ko) * | 2018-12-27 | 2021-12-06 | 주식회사 바이오포아 | 돼지 생식기 및 호흡기 증후군 바이러스의 키메라 바이러스 및 이를 이용한 백신 |
| US12214032B2 (en) | 2019-08-29 | 2025-02-04 | Elanco Uk Ah Limited | Porcine Reproductive and Respiratory Syndrome vaccine virus |
| CN110894243B (zh) * | 2019-12-16 | 2021-07-13 | 中国农业大学 | 一种猪蓝耳病毒嵌合抗原以及检测猪蓝耳病毒抗体的胶体金免疫层析试纸条 |
| KR102764120B1 (ko) | 2019-12-31 | 2025-02-06 | 엘릭서젠 쎄라퓨틱스, 인크. | 핵산 및 단백질의 세포 및 조직으로의 온도-기반 일시적 전달 |
| JP2021153692A (ja) * | 2020-03-25 | 2021-10-07 | 株式会社三共 | 遊技機 |
| KR102319508B1 (ko) * | 2020-07-27 | 2021-10-28 | 연세대학교 산학협력단 | 인체 감염형 낙타 유래 메르스코로나바이러스 검출용 바이오마커 및 이의 용도 |
| CN113969267B (zh) * | 2021-11-15 | 2024-02-27 | 中国农业大学 | 一种猪繁殖与呼吸综合征突变病毒及其构建方法与应用 |
| WO2024077281A2 (en) * | 2022-10-06 | 2024-04-11 | Cornell University | Genotyping and sequencing assays for prrsv |
| KR20240146158A (ko) * | 2023-03-27 | 2024-10-08 | 주식회사 케어사이드 | 돼지생식기호흡기증후군 키메릭 바이러스 및 이를 이용한 백신 조성물 |
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| US3137631A (en) | 1959-12-01 | 1964-06-16 | Faberge Inc | Encapsulation in natural products |
| US3959457A (en) | 1970-06-05 | 1976-05-25 | Temple University | Microparticulate material and method of making such material |
| US4015100A (en) | 1974-01-07 | 1977-03-29 | Avco Everett Research Laboratory, Inc. | Surface modification |
| EP0000062A1 (en) | 1977-06-07 | 1978-12-20 | Joseph George Spitzer | Vapor tap valve for aerosol containers used with inflammable propellants, and container provided therewith |
| US4205060A (en) | 1978-12-20 | 1980-05-27 | Pennwalt Corporation | Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use |
| ZA864879B (en) | 1985-07-08 | 1987-03-25 | Wallone Region | Vaccines and diagnostics derived from boving diarrhoea virus |
| NZ222465A (en) | 1986-11-07 | 1992-11-25 | Pasteur Institut | Nanb (non a, non b hepatitis viral) antigen |
| DE69201441T3 (de) | 1991-06-06 | 2008-12-04 | Boehringer Ingelheim Vetmedica Gmbh | Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits. |
| US6042830A (en) | 1992-08-05 | 2000-03-28 | Boehringer Ingelheim Vetmedica, Inc. | Viral agent associated with mystery swine disease |
| AU2684792A (en) | 1991-10-14 | 1993-05-21 | Akzo Nobel N.V. | Porcine reproductive respiratory syndrome vaccine and diagnostic |
| FR2686097B1 (fr) | 1992-01-14 | 1994-12-30 | Rhone Merieux | Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie. |
| US5695766A (en) | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
| ES2074950B1 (es) | 1993-09-17 | 1996-03-16 | Iberica Cyanamid | Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda. |
| DE69522984T2 (de) | 1994-04-11 | 2002-04-25 | Akzo Nobel Nv | Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Schweins |
| DK53595A (da) | 1994-05-13 | 1995-11-14 | Iberica Cyanamid | Rekombinante PRRSV-proteiner, diagnostiske kits og vaccine indeholdende sådanne rekombinante PRRSV-proteiner |
| DE69632658T2 (de) | 1995-03-14 | 2005-06-09 | Akzo Nobel N.V. | Expression in der selben Zelle von Polypeptide vom schweinen reproduktiven und respiratorischen Syndrom |
| ES2102971B1 (es) | 1996-01-25 | 1998-03-01 | Hipra Lab Sa | Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion. |
| US5866401A (en) | 1996-03-01 | 1999-02-02 | Schering Corporation | Porcine reproductive and respiratory syndrome vaccine |
| ES2157522T3 (es) | 1996-10-09 | 2001-08-16 | Akzo Nobel Nv | Cepas de vacunas europeas del virus del sindrome respiratorio reproductor porcino (prrsv). |
| EP0839912A1 (en) | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| US20040224327A1 (en) | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| EP1882696A3 (en) | 1997-05-06 | 2008-03-05 | Boehringer Ingelheim Vetmedica Gmbh | PRRSV antigenic sites identifying peptide sequences of PRRS virus for use in vaccines or diagnostic assays |
| NZ513289A (en) | 1998-12-22 | 2003-04-29 | Pfizer Prod Inc | Infectious cDNA clone of north american procine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| JP3961222B2 (ja) | 1999-03-08 | 2007-08-22 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | Ｐｒｒｓｖワクチン |
| EP1183332B1 (en) | 1999-04-22 | 2010-07-14 | United States Department Of Agriculture | Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142 |
| WO2002095040A1 (en) | 2001-05-21 | 2002-11-28 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Delections in arterivirus replicons |
| CA2400583A1 (en) | 2000-02-08 | 2001-08-16 | Regents Of The University Of Minnesota | Porcine reproductive and respiratory syndrome virus and methods of use |
| EP1156111A1 (en) | 2000-05-19 | 2001-11-21 | Stichting Dienst Landbouwkundig Onderzoek | Chimeric arterivirus-like particles |
| EP1350840B1 (en) | 2002-04-05 | 2012-05-09 | Boehringer Ingelheim Vetmedica GmbH | Adaptation sites of PRRSV |
| US7722878B2 (en) | 2004-06-17 | 2010-05-25 | Boehringer Ingelheim Vetmedica, Inc. | PRRSV subunit vaccines |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| CA2587321A1 (en) | 2005-01-13 | 2006-07-20 | Boehringer Ingelheim Vetmedica Gmbh | Improved prrs vaccines |
| WO2008121958A1 (en) | 2007-04-02 | 2008-10-09 | Boehringer Ingelheim Vetmedica, Inc. | Use of prrsv vaccines to reduce pcv2 viremia |
| ES2389748T3 (es) * | 2007-06-25 | 2012-10-31 | South Dakota State University | Virus del síndrome reproductivo y respiratorio porcino de tipo 1 norteamericano recombinante y métodos de uso |
| JP5619004B2 (ja) | 2008-08-25 | 2014-11-05 | ベーリンガーインゲルハイム フェトメディカ インコーポレイテッド | 高病原性ブタ繁殖・呼吸障害症候群（ｈｐｐｒｒｓ）のワクチン |
| WO2010084648A1 (ja) | 2009-01-20 | 2010-07-29 | シャープ株式会社 | 照明装置、表示装置、及びテレビ受信装置 |
| WO2011128415A1 (en) | 2010-04-16 | 2011-10-20 | Universiteit Gent | Cross-protecting vaccine for porcine reproductive and respiratory syndrome virus |
| WO2012110489A2 (en) | 2011-02-17 | 2012-08-23 | Boehringer Ingelheim Vetmedica Gmbh | Novel european prrsv strain |
| AU2012217170B2 (en) | 2011-02-17 | 2016-07-28 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of PRRSV |
| WO2013017568A1 (en) | 2011-07-29 | 2013-02-07 | Boehringer Ingelheim Vetmedica Gmbh | INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF |
| EA032389B1 (ru) * | 2012-02-14 | 2019-05-31 | Мериал, Инк. | Рекомбинантные поксвирусные векторы, кодирующие и экспрессирующие гликопротеин g вируса бешенства и полипептид oxl, и вакцины, созданные на их основе, используемые в способе вакцинации животных против бешенства |
| MX2014013964A (es) * | 2012-05-17 | 2015-03-04 | Zoetis Llc | Vacunacion eficaz contral el virus del sindrome reproductivo y respiratorio porcino (prrs) antes del destete. |
| US9579373B2 (en) | 2013-03-15 | 2017-02-28 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
| EP3084460B1 (en) * | 2013-12-19 | 2021-10-06 | Koninklijke Philips N.V. | Phase-sensitive inversion recovery mri with water/fat separation |
| AU2014369774B2 (en) | 2013-12-20 | 2020-11-26 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus variant, European PRRS virus cDNA clone, and uses thereof |
-
2014
- 2014-12-19 AU AU2014369774A patent/AU2014369774B2/en active Active
- 2014-12-19 ES ES19165389T patent/ES2940691T3/es active Active
- 2014-12-19 KR KR1020167019672A patent/KR102270344B1/ko active Active
- 2014-12-19 WO PCT/EP2014/078929 patent/WO2015092058A1/en not_active Ceased
- 2014-12-19 EP EP14827219.8A patent/EP3083947B1/en active Active
- 2014-12-19 DK DK19165389.8T patent/DK3591042T5/da active
- 2014-12-19 KR KR1020217019360A patent/KR102446025B1/ko active Active
- 2014-12-19 US US15/105,760 patent/US10010601B2/en active Active
- 2014-12-19 EP EP19165389.8A patent/EP3591042B1/en active Active
- 2014-12-19 JP JP2016540591A patent/JP6886291B2/ja active Active
- 2014-12-19 HU HUE19165389A patent/HUE061768T2/hu unknown
- 2014-12-19 MX MX2020010248A patent/MX2020010248A/es unknown
- 2014-12-19 EA EA201600476A patent/EA039060B1/ru unknown
- 2014-12-19 CN CN201480068965.2A patent/CN105829528B/zh active Active
- 2014-12-19 MX MX2016007737A patent/MX375528B/es active IP Right Grant
- 2014-12-19 ES ES14827219T patent/ES2729838T3/es active Active
- 2014-12-19 DK DK14827219.8T patent/DK3083947T3/da active
- 2014-12-19 CA CA2930042A patent/CA2930042C/en active Active
-
2018
- 2018-06-01 US US15/995,560 patent/US10639364B2/en active Active
-
2019
- 2019-12-20 JP JP2019230014A patent/JP2020054380A/ja not_active Withdrawn
-
2021
- 2021-02-25 AU AU2021201224A patent/AU2021201224B2/en active Active
- 2021-03-24 JP JP2021049537A patent/JP7158523B2/ja active Active
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