CA2928464A1 - Biomarqueur de l'activite de melk et ses procedes d'utilisation - Google Patents

Biomarqueur de l'activite de melk et ses procedes d'utilisation Download PDF

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Publication number
CA2928464A1
CA2928464A1 CA2928464A CA2928464A CA2928464A1 CA 2928464 A1 CA2928464 A1 CA 2928464A1 CA 2928464 A CA2928464 A CA 2928464A CA 2928464 A CA2928464 A CA 2928464A CA 2928464 A1 CA2928464 A1 CA 2928464A1
Authority
CA
Canada
Prior art keywords
human
phosphorylated
ortholog
melk
histone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2928464A
Other languages
English (en)
Inventor
Jean Zhao
Yubao Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dana Farber Cancer Institute Inc
Original Assignee
Dana Farber Cancer Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Institute Inc filed Critical Dana Farber Cancer Institute Inc
Publication of CA2928464A1 publication Critical patent/CA2928464A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2928464A 2013-11-12 2014-11-12 Biomarqueur de l'activite de melk et ses procedes d'utilisation Abandoned CA2928464A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361902877P 2013-11-12 2013-11-12
US61/902,877 2013-11-12
US201461954046P 2014-03-17 2014-03-17
US61/954,046 2014-03-17
PCT/US2014/065173 WO2015073509A2 (fr) 2013-11-12 2014-11-12 Biomarqueur de l'activité de melk et ses procédés d'utilisation

Publications (1)

Publication Number Publication Date
CA2928464A1 true CA2928464A1 (fr) 2015-05-21

Family

ID=55867713

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2928464A Abandoned CA2928464A1 (fr) 2013-11-12 2014-11-12 Biomarqueur de l'activite de melk et ses procedes d'utilisation

Country Status (5)

Country Link
EP (1) EP3068930A4 (fr)
CN (1) CN106232878A (fr)
AU (1) AU2014348780B2 (fr)
CA (1) CA2928464A1 (fr)
WO (1) WO2015073509A2 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1651956A4 (fr) * 2003-08-14 2008-08-20 Exelixis Inc Melks utilises comme modificateurs du mecanisme d'action de rac et procedes d'utilisation
EP2574929A1 (fr) * 2011-09-28 2013-04-03 IMG Institut für medizinische Genomforschung Planungsgesellschaft M.B.H. Marqueur pour le diagnostic du cancer de la prostate
CN103173527A (zh) * 2011-12-22 2013-06-26 上海生物芯片有限公司 Melk基因的用途
EP2753329B1 (fr) * 2012-01-19 2017-08-09 OncoTherapy Science, Inc. Dérivés de 1,5-naphtyridine comme inhibiteurs de melk

Also Published As

Publication number Publication date
WO2015073509A2 (fr) 2015-05-21
EP3068930A4 (fr) 2017-10-04
WO2015073509A8 (fr) 2016-05-26
AU2014348780B2 (en) 2018-12-13
CN106232878A (zh) 2016-12-14
WO2015073509A3 (fr) 2016-01-14
AU2014348780A8 (en) 2016-06-30
EP3068930A2 (fr) 2016-09-21
AU2014348780A1 (en) 2016-06-02

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20210203