CA2926253A1 - Portable testing device for analyzing biological samples - Google Patents
Portable testing device for analyzing biological samples Download PDFInfo
- Publication number
- CA2926253A1 CA2926253A1 CA2926253A CA2926253A CA2926253A1 CA 2926253 A1 CA2926253 A1 CA 2926253A1 CA 2926253 A CA2926253 A CA 2926253A CA 2926253 A CA2926253 A CA 2926253A CA 2926253 A1 CA2926253 A1 CA 2926253A1
- Authority
- CA
- Canada
- Prior art keywords
- sample
- light
- testing device
- housing
- apertures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 496
- 239000012472 biological sample Substances 0.000 title claims abstract description 292
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- 239000011541 reaction mixture Substances 0.000 claims description 51
- 238000002360 preparation method Methods 0.000 claims description 46
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0332—Cuvette constructions with temperature control
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/021—Identification, e.g. bar codes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/024—Storing results with means integrated into the container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/025—Displaying results or values with integrated means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0325—Cells for testing reactions, e.g. containing reagents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6482—Sample cells, cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/022—Casings
- G01N2201/0221—Portable; cableless; compact; hand-held
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/023—Controlling conditions in casing
- G01N2201/0231—Thermostating
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Clinical Laboratory Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Optics & Photonics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361887754P | 2013-10-07 | 2013-10-07 | |
| US61/887,754 | 2013-10-07 | ||
| US201461926759P | 2014-01-13 | 2014-01-13 | |
| US61/926,759 | 2014-01-13 | ||
| PCT/US2014/059487 WO2015054245A1 (en) | 2013-10-07 | 2014-10-07 | Portable testing device for analyzing biological samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2926253A1 true CA2926253A1 (en) | 2015-04-16 |
Family
ID=52813577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2926253A Pending CA2926253A1 (en) | 2013-10-07 | 2014-10-07 | Portable testing device for analyzing biological samples |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10036058B2 (de) |
| EP (1) | EP3055407B1 (de) |
| CN (1) | CN105765054A (de) |
| AU (2) | AU2014332126B2 (de) |
| BR (1) | BR112016007781B1 (de) |
| CA (1) | CA2926253A1 (de) |
| ES (1) | ES2906369T3 (de) |
| WO (1) | WO2015054245A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD753311S1 (en) | 2011-10-12 | 2016-04-05 | Alere Switzerland Gmbh | Isothermal nucleic acid amplification meter |
| EP2945742A4 (de) | 2013-01-18 | 2016-09-21 | Biomeme Inc | Analysevorrichtung |
| EP3055407B1 (de) | 2013-10-07 | 2022-01-12 | Agdia Inc. | Optische anordnung zur verwendung in tragbarer testvorrichtung zur analyse biologischer proben |
| TW201723482A (zh) * | 2015-08-18 | 2017-07-01 | 新加坡科技研究局 | 光學結構及光學光偵測系統 |
| CN108107024A (zh) * | 2016-11-25 | 2018-06-01 | 苏州百源基因技术有限公司 | 一种智能化pcr仪 |
| JP1588984S (de) * | 2017-02-07 | 2017-10-30 | ||
| CN107497519B (zh) * | 2017-10-17 | 2020-01-07 | 中华人民共和国南通出入境检验检疫局 | 方便快速查找的医学检验试管架 |
| TW201930844A (zh) * | 2017-12-15 | 2019-08-01 | 美商拜歐迷蜜公司 | 用於分析樣本之可攜帶式裝置及方法 |
| CA2998927A1 (en) * | 2018-03-22 | 2019-09-22 | Alpha Micro Tech Inc. | Data logger for dental autoclave |
| CN108531390A (zh) * | 2018-04-11 | 2018-09-14 | 张薇 | 一种便携式可用于现场检测核酸的设备 |
| WO2020014296A1 (en) * | 2018-07-12 | 2020-01-16 | Luminex Corporation | Systems and methods for performing variable sample preparation and analysis processes |
| CN113874708A (zh) | 2019-03-21 | 2021-12-31 | 生米公司 | 多功能分析装置 |
| CA3141275A1 (en) * | 2019-06-18 | 2020-12-24 | Biomeme, Inc. | Systems for sample analysis |
| CN114667096A (zh) * | 2019-07-19 | 2022-06-24 | Dh诊断有限责任公司 | 用于血液样本采集和处理的系统和方法 |
| TWI722785B (zh) | 2020-01-31 | 2021-03-21 | 台達電子工業股份有限公司 | 光學校正工具 |
| KR20210128632A (ko) * | 2020-04-17 | 2021-10-27 | 커넥타젠(주) | 포터블 등온 증폭 검출 장치 |
| WO2021246745A1 (en) * | 2020-06-03 | 2021-12-09 | Seegene, Inc. | Optical signal detection device for detecting multiple optical signals for multiple target analytes from sample |
| KR102612446B1 (ko) * | 2020-08-03 | 2023-12-12 | 한국전자통신연구원 | 유전자분석기 및 이를 이용한 유전자 분석 시스템과 방법 |
| WO2022061105A1 (en) | 2020-09-18 | 2022-03-24 | Biomeme, Inc. | Portable devices and methods for analyzing samples |
| CN216274121U (zh) * | 2021-10-12 | 2022-04-12 | 江苏汇先医药技术有限公司 | 一种手持式lamp检测仪及系统 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5184020A (en) | 1989-10-26 | 1993-02-02 | Hearst David P | Device and method for photoactivation |
| US5503721A (en) | 1991-07-18 | 1996-04-02 | Hri Research, Inc. | Method for photoactivation |
| KR100236506B1 (ko) | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
| CA2129787A1 (en) | 1993-08-27 | 1995-02-28 | Russell G. Higuchi | Monitoring multiple amplification reactions simultaneously and analyzing same |
| US5585069A (en) * | 1994-11-10 | 1996-12-17 | David Sarnoff Research Center, Inc. | Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis |
| US6084683A (en) | 1996-05-28 | 2000-07-04 | Bruno; Alfredo Emilio | Optical detection apparatus for chemical analyses of small volumes of samples |
| DK2308995T3 (da) | 1997-02-28 | 2015-08-03 | Cepheid | Kemisk reaktionsenhed med varmeveksler og optisk detektor |
| US6043880A (en) * | 1997-09-15 | 2000-03-28 | Becton Dickinson And Company | Automated optical reader for nucleic acid assays |
| US6369893B1 (en) | 1998-05-19 | 2002-04-09 | Cepheid | Multi-channel optical detection system |
| US6699713B2 (en) | 2000-01-04 | 2004-03-02 | The Regents Of The University Of California | Polymerase chain reaction system |
| US20020132360A1 (en) | 2000-11-17 | 2002-09-19 | Flir Systems Boston, Inc. | Apparatus and methods for infrared calorimetric measurements |
| TWI243242B (en) | 2001-01-26 | 2005-11-11 | Biocal Technology Inc | Optical detection in a multi-channel bio-separation system |
| JP4569030B2 (ja) | 2001-04-23 | 2010-10-27 | 東ソー株式会社 | 外部光下で計測可能な蛍光検出方法、および装置 |
| US6995841B2 (en) | 2001-08-28 | 2006-02-07 | Rice University | Pulsed-multiline excitation for color-blind fluorescence detection |
| US7846315B2 (en) | 2002-01-28 | 2010-12-07 | Qiagen Sciences, Llc | Integrated bio-analysis and sample preparation system |
| US20070141567A1 (en) | 2002-11-13 | 2007-06-21 | Wulfman David R | Waveguide system for detection of fluorescently labeled nucleic acid sequences |
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2014
- 2014-10-07 EP EP14852273.3A patent/EP3055407B1/de active Active
- 2014-10-07 CN CN201480064137.1A patent/CN105765054A/zh active Pending
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- 2014-10-07 CA CA2926253A patent/CA2926253A1/en active Pending
- 2014-10-07 AU AU2014332126A patent/AU2014332126B2/en active Active
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| US10036058B2 (en) | 2018-07-31 |
| US10731207B2 (en) | 2020-08-04 |
| ES2906369T3 (es) | 2022-04-18 |
| BR112016007781A8 (pt) | 2020-03-10 |
| AU2014332126B2 (en) | 2019-10-31 |
| EP3055407A4 (de) | 2017-11-08 |
| EP3055407A1 (de) | 2016-08-17 |
| US20160265040A1 (en) | 2016-09-15 |
| WO2015054245A1 (en) | 2015-04-16 |
| EP3055407B1 (de) | 2022-01-12 |
| US20190062823A1 (en) | 2019-02-28 |
| AU2014332126A1 (en) | 2016-05-05 |
| BR112016007781B1 (pt) | 2021-12-28 |
| AU2020200718A1 (en) | 2020-02-20 |
| CN105765054A (zh) | 2016-07-13 |
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