CA2924714C - Toothpaste for delivering allergens to oral mucosa - Google Patents

Toothpaste for delivering allergens to oral mucosa Download PDF

Info

Publication number
CA2924714C
CA2924714C CA2924714A CA2924714A CA2924714C CA 2924714 C CA2924714 C CA 2924714C CA 2924714 A CA2924714 A CA 2924714A CA 2924714 A CA2924714 A CA 2924714A CA 2924714 C CA2924714 C CA 2924714C
Authority
CA
Canada
Prior art keywords
toothpaste
allergen
pro
allergens
volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2924714A
Other languages
English (en)
French (fr)
Other versions
CA2924714A1 (en
Inventor
Michael Nelson
Erick Berglund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allovate LLC
Original Assignee
Allovate LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allovate LLC filed Critical Allovate LLC
Publication of CA2924714A1 publication Critical patent/CA2924714A1/en
Application granted granted Critical
Publication of CA2924714C publication Critical patent/CA2924714C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/985Skin or skin outgrowth, e.g. hair, nails
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/88Two- or multipart kits
    • A61K2800/882Mixing prior to application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92Oral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Tropical Medicine & Parasitology (AREA)
CA2924714A 2013-09-19 2014-09-19 Toothpaste for delivering allergens to oral mucosa Active CA2924714C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361879801P 2013-09-19 2013-09-19
US201361879779P 2013-09-19 2013-09-19
US61/879,801 2013-09-19
US61/879,779 2013-09-19
PCT/US2014/056562 WO2015042402A1 (en) 2013-09-19 2014-09-19 Toothpaste for delivering allergens to oral mucosa

Publications (2)

Publication Number Publication Date
CA2924714A1 CA2924714A1 (en) 2015-03-26
CA2924714C true CA2924714C (en) 2024-04-09

Family

ID=52689443

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2924714A Active CA2924714C (en) 2013-09-19 2014-09-19 Toothpaste for delivering allergens to oral mucosa

Country Status (10)

Country Link
US (4) US10485867B2 (https=)
EP (1) EP3046633A4 (https=)
JP (3) JP2016537299A (https=)
KR (1) KR102385900B1 (https=)
AU (3) AU2014321402B2 (https=)
BR (1) BR112016006064B1 (https=)
CA (1) CA2924714C (https=)
EA (1) EA035045B1 (https=)
IL (1) IL244636B (https=)
WO (1) WO2015042402A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA035045B1 (ru) 2013-09-19 2020-04-21 АЛЛОВЕЙТ, ЭлЭлСи Составы зубной пасты для доставки аллергенов в слизистую оболочку полости рта
US10166286B2 (en) 2015-02-20 2019-01-01 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10149904B2 (en) 2015-02-20 2018-12-11 The Board Of Trusteees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US11452774B2 (en) 2015-02-20 2022-09-27 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
MA41558B1 (fr) * 2015-02-20 2023-02-28 Univ Leland Stanford Junior Compositions d'allergènes mélangés et leurs procédés d'utilisation
US10143742B2 (en) 2015-02-20 2018-12-04 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
JP6130568B1 (ja) 2016-08-26 2017-05-17 日本製紙株式会社 反芻動物用飼料ペレット
JP6196716B1 (ja) * 2016-08-26 2017-09-13 日本製紙株式会社 反芻動物用飼料ペレット
NZ760884A (en) 2017-07-18 2023-05-26 Nestle Sa Methods for making mixed allergen compositions
CN113507844A (zh) 2019-01-23 2021-10-15 前品牌股份有限公司 制备混合型过敏原组合物的方法

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2112913A1 (en) 1991-07-12 1993-01-21 Irwin J. Griffith Allergenic proteins and peptides from japanese cedar pollen
US5183829A (en) * 1991-09-27 1993-02-02 Applied Analytical Industries, Inc. Oral liquid compositions of non-steroidal anti-inflammatory drugs
JP3345133B2 (ja) 1992-12-21 2002-11-18 サンスター株式会社 練歯磨組成物
JPH0959179A (ja) * 1995-08-28 1997-03-04 Japan Tobacco Inc スギ花粉症予防性を有する口腔衛生剤
US6042812A (en) 1996-11-26 2000-03-28 The Procter & Gamble Company Flavor systems for oral care products
JP3719874B2 (ja) 1998-04-24 2005-11-24 サンスター株式会社 口腔用組成物
IT1311889B1 (it) 1999-03-12 2002-03-20 Farmaceutici Dott Ciccarelli S Paste dentifricie.
US6342205B1 (en) 1999-10-29 2002-01-29 J. M. Huber Corporation High water content dentifrice composition and method of making the same
MXPA02004787A (es) 1999-11-12 2002-08-30 Procter & Gamble Composiciones bucales estanosas mejoradas.
US20040191276A1 (en) * 1999-11-30 2004-09-30 Cutispharma, Inc. Compositions and kits for compounding pharmaceuticals
US6780416B1 (en) 2000-02-18 2004-08-24 Ecole Polytechnique Federale De Lausanne Bee venom polypeptides and methods of use thereof
US6773695B2 (en) * 2000-10-05 2004-08-10 Mannkind Corporation Modulation of allergic response
US6416745B1 (en) * 2001-05-03 2002-07-09 Block Drug Company, Inc. Dental composition for treating hypersensitive teeth
US6689569B2 (en) 2001-08-14 2004-02-10 Immunosciences Lab., Inc. Saliva test for detection of food allergy, candidiasis, microflora imbalance, intestinal barrier dysfunction and humoral immunodeficiencies
US6863901B2 (en) 2001-11-30 2005-03-08 Collegium Pharmaceutical, Inc. Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
ATE414534T1 (de) 2001-12-05 2008-12-15 Circassia Ltd Immunotherapeutische methoden und systeme
US8133991B2 (en) 2002-07-03 2012-03-13 Kao Corporation Allergen inactivating agent
MXPA05005528A (es) 2002-11-26 2006-04-05 Alk Abello As Producto farmaceutico de alergeno.
US7923209B2 (en) 2003-03-14 2011-04-12 Anergis, S.A. Allergen peptide fragments and use thereof
US7087219B2 (en) 2003-05-28 2006-08-08 Stanislaw R. Burzynski Toothpaste containing anticancer agents
US20050084551A1 (en) * 2003-09-26 2005-04-21 Jensen Claude J. Morinda citrifolia-based oral care compositions and methods
EP1697033B1 (en) 2003-12-19 2011-04-13 Alk-Abelló A/S Process for cryogranulation and storage of allergens
GB0401238D0 (en) 2004-01-21 2004-02-25 Molecularnature Ltd Immunomodulatory alkaloids
DE102004034418B4 (de) * 2004-07-15 2009-06-25 Schott Ag Verfahren zur Herstellung struktuierter optischer Filterschichten auf Substraten
KR100958505B1 (ko) 2004-07-18 2010-05-17 씨에스엘 리미티드 면역자극 복합체 및 향상된 인터페론-감마 반응을 유도하기위한 올리고뉴클레오티드 제제
US7367476B2 (en) 2004-08-30 2008-05-06 Rieke Corporation Airless dispensing pump with tamper evidence features
US7654418B2 (en) 2004-08-30 2010-02-02 Rieke Corporation Airless dispensing pump
US8974772B2 (en) * 2004-12-28 2015-03-10 Colgate-Palmolive Company Two phase toothpaste composition
WO2006072251A1 (en) 2005-01-07 2006-07-13 Alk-Abellò A/S Method of preventive treatment of allergy by oromucosal administration of an allergy vaccine
US20060269576A1 (en) 2005-05-27 2006-11-30 Curalogic, A/S Non-injection immunotherapy
US20070031539A1 (en) 2005-08-02 2007-02-08 Calton Jim S Jr Personal caffeine delivery pouch
KR20080070851A (ko) * 2005-11-04 2008-07-31 알크-아벨로 에이/에스 구강점막 투여용 액상 알레르기 백신 제형의 용도
US7786089B2 (en) 2005-12-20 2010-08-31 Idera Pharmaceuticals, Inc. Immunostimulatory activity of immune modulatory oligonucleotides (IMO™) containing different lengths of palindromic segments
EP1986601A2 (en) 2006-01-20 2008-11-05 MonoSol Rx LLC Film lined pouch and method of manufacturing this pouch
US20080152695A1 (en) 2006-06-14 2008-06-26 Clark Richard T Oral/buccal transmucosal delivery methods for electrolyte compositions including xylitol
EP1958645A1 (en) 2007-02-13 2008-08-20 Biomay AG Peptides derived from the major allergen of ragweed (Ambrosia artemisiifolia) and uses thereof
US20080302682A1 (en) 2007-06-11 2008-12-11 Radi Medical Biodegradable Ab Pouch for tobacco or tobacco substitute
WO2008156704A2 (en) 2007-06-14 2008-12-24 The Board Of Regents Of The University Of Texas System Antibody-mediated modulation of allergy
US7887821B2 (en) 2007-12-20 2011-02-15 Alk-Abello A/S Process for producing an allergen extract
US20100018540A1 (en) 2008-07-28 2010-01-28 David James Doolittle Smokeless tobacco products and processes
US20100183523A1 (en) * 2009-01-22 2010-07-22 Wagner Richard E Dental composition and method
ES2658166T3 (es) 2009-03-13 2018-03-08 Excellent Tech Products I Sverige Ab Producto para administración oral
WO2010128364A1 (en) 2009-05-04 2010-11-11 Stallergenes S.A. Method for the prevention or treatment of taxodiaceae pollen allergy
WO2011112788A1 (en) 2010-03-12 2011-09-15 Antigen Laboratories, Inc. Methods of treating allergies with substantially phenol-free carriers
JP6062851B2 (ja) 2010-04-30 2017-01-18 アロヴェイト・エルエルシー 口腔粘膜を介してアレルギーを減感作するための方法、物品及びキット
US8631975B2 (en) 2011-04-25 2014-01-21 Toly Korea, Inc. Airless pump and cosmetic container having the same
WO2012162558A2 (en) 2011-05-24 2012-11-29 Sunstar Americas, Inc. Delivery system
EA035045B1 (ru) * 2013-09-19 2020-04-21 АЛЛОВЕЙТ, ЭлЭлСи Составы зубной пасты для доставки аллергенов в слизистую оболочку полости рта
EP2952200A1 (en) 2014-06-04 2015-12-09 Alk-Abelló A/S Allergen for prophylactic treatment of allergy

Also Published As

Publication number Publication date
EA035045B1 (ru) 2020-04-21
US20160228539A1 (en) 2016-08-11
EA201690612A1 (ru) 2016-08-31
US10485867B2 (en) 2019-11-26
US11980664B2 (en) 2024-05-14
AU2014321402B2 (en) 2019-07-25
US20200046828A1 (en) 2020-02-13
EP3046633A4 (en) 2017-03-15
US12527861B2 (en) 2026-01-20
US20240252626A1 (en) 2024-08-01
BR112016006064A2 (pt) 2017-08-01
KR20160067125A (ko) 2016-06-13
IL244636B (en) 2021-09-30
AU2019253826B2 (en) 2021-05-20
BR112016006064A8 (pt) 2018-02-06
KR102385900B1 (ko) 2022-04-11
WO2015042402A1 (en) 2015-03-26
IL244636A0 (en) 2016-04-21
JP2019142897A (ja) 2019-08-29
AU2021217993A1 (en) 2021-09-02
JP7209425B2 (ja) 2023-01-20
EP3046633A1 (en) 2016-07-27
AU2019253826A1 (en) 2019-11-14
US20210187103A1 (en) 2021-06-24
CA2924714A1 (en) 2015-03-26
AU2021217993B2 (en) 2023-08-17
US10967059B2 (en) 2021-04-06
AU2014321402A1 (en) 2016-07-14
JP2021098705A (ja) 2021-07-01
BR112016006064B1 (pt) 2020-07-07
JP2016537299A (ja) 2016-12-01

Similar Documents

Publication Publication Date Title
US12527861B2 (en) Toothpaste for delivery of allergens to oral mucosa
AU2005322191B2 (en) Method of reducing oral tissue inflammation using magnolia extract
JP5665888B2 (ja) 口腔ケア組成物
TR201809495T4 (tr) Kserostomi̇ veya kuru ağiz tedavi̇si̇ne yöneli̇k bi̇leşi̇m.
CN103025303A (zh) 经由口腔粘膜变应性脱敏的方法、制品和试剂盒
EP2709586B1 (en) Oral care composition for treating dry mouth
Hattab Chewing gum for oral and dental health: a review
AU2005319562B2 (en) Oral care malodor composition
CN102448437B (zh) 用于缓解唾液分泌过少和提供口腔舒适的组合物和方法
CN104066417B (zh) 包含异丁基厚朴酚的口腔护理组合物
US20060193795A1 (en) Appetite suppressant mouth spray
US20100158820A1 (en) Xylitol dental maintenance system
WO2008008596A2 (en) Method of reducing inflammation
KR20180047705A (ko) 연교 추출물을 포함하는 구강질환 예방 또는 치료용 조성물
JP2015508817A (ja) オーラル・ケア組成物

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190912

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 10TH ANNIV.) - STANDARD

Year of fee payment: 10

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20240913

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20240913

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20240913

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 11TH ANNIV.) - STANDARD

Year of fee payment: 11

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250912

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250912