CA2920456A1 - Anti-aging compositions comprising bile acid-fatty acid conjugates - Google Patents

Anti-aging compositions comprising bile acid-fatty acid conjugates Download PDF

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Publication number
CA2920456A1
CA2920456A1 CA2920456A CA2920456A CA2920456A1 CA 2920456 A1 CA2920456 A1 CA 2920456A1 CA 2920456 A CA2920456 A CA 2920456A CA 2920456 A CA2920456 A CA 2920456A CA 2920456 A1 CA2920456 A1 CA 2920456A1
Authority
CA
Canada
Prior art keywords
acid
skin
composition
fabac
aging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2920456A
Other languages
English (en)
French (fr)
Inventor
Nava Dayan
Allen BAHARAFF
Original Assignee
GALDERM THERAPEUTICS Ltd
Galmed Research and Development Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GALDERM THERAPEUTICS Ltd, Galmed Research and Development Ltd filed Critical GALDERM THERAPEUTICS Ltd
Publication of CA2920456A1 publication Critical patent/CA2920456A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/522Antioxidants; Radical scavengers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
CA2920456A 2013-08-08 2014-08-07 Anti-aging compositions comprising bile acid-fatty acid conjugates Abandoned CA2920456A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL227890 2013-08-08
IL227890A IL227890A0 (en) 2013-08-08 2013-08-08 Antiaging compounds containing bile acid and fatty acid conjugates
PCT/IL2014/050717 WO2015019358A1 (en) 2013-08-08 2014-08-07 Anti-aging compositions comprising bile acid-fatty acid conjugates

Publications (1)

Publication Number Publication Date
CA2920456A1 true CA2920456A1 (en) 2015-02-12

Family

ID=50022996

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2920456A Abandoned CA2920456A1 (en) 2013-08-08 2014-08-07 Anti-aging compositions comprising bile acid-fatty acid conjugates

Country Status (9)

Country Link
US (1) US20160175223A1 (https=)
EP (1) EP3030221A4 (https=)
JP (1) JP2016527306A (https=)
CN (1) CN105611910A (https=)
AU (1) AU2014304078A1 (https=)
CA (1) CA2920456A1 (https=)
HK (1) HK1224198A1 (https=)
IL (2) IL227890A0 (https=)
WO (1) WO2015019358A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160175324A1 (en) * 2013-08-08 2016-06-23 Galderm Therapeutics Ltd. Anti-acne compositions comprising bile acid-fatty acid conjugates
US11571431B2 (en) 2013-12-04 2023-02-07 Galmed Research And Development Ltd Aramchol salts
WO2016127102A2 (en) 2015-02-06 2016-08-11 Ernesto Abel-Santos Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis
US10849911B2 (en) 2015-06-10 2020-12-01 Galmed Research And Development Ltd. Low dose compositions of Aramachol salts
IL243707A0 (en) 2016-01-20 2016-05-01 Galmed Res And Dev Ltd Treatment to regulate the microbiota in the intestine
US11197870B2 (en) 2016-11-10 2021-12-14 Galmed Research And Development Ltd Treatment for hepatic fibrosis
CN109503693B (zh) * 2018-12-12 2021-04-06 合肥工业大学 一种利用胆酸为原料合成Aramchol的工艺
JP2021100925A (ja) * 2019-10-31 2021-07-08 共栄化学工業株式会社 皮膚外用剤
WO2023287261A1 (ko) * 2021-07-16 2023-01-19 주식회사 스카이테라퓨틱스 담즙산 또는 담즙산 염의 분자 회합체를 포함하는 화장료 조성물
EP4398890A4 (en) * 2021-09-09 2025-07-30 The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The Univ Of Nevada Las Ve C. Difficile Spore Germination Inhibitors
CN117398391A (zh) * 2022-07-14 2024-01-16 爱医谷(苏州)生物科技有限公司 一种用于抵抗衰老的组合物及其用途或方法
CN116236490A (zh) * 2023-02-14 2023-06-09 四川大学 脱氧胆酸的用途及药物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
IL142650A (en) * 1998-04-08 2007-06-03 Galmed Int Ltd Use of bile acid conjugates or bile salts and fatty acids or fatty acids in the preparation of pharmaceuticals for lowering cholesterol, for the treatment of fatty liver and for the treatment of hyperglycemia and diabetes
US6019992A (en) * 1998-12-04 2000-02-01 Chesebrough-Pond's Usa Co. Cosmetic skin care compositions containing 4-chromanone
US8975246B2 (en) * 2001-04-17 2015-03-10 Galmed Research And Development Ltd. Bile acid or bile salt fatty acid conjugates
US20060127468A1 (en) * 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
ES2296463B1 (es) * 2005-07-13 2009-02-16 Universidade De Santiago Compostela Nuevos amidoderivados de acidos billares funcionalizados en la posicion 3 del anillo a. procedimientos para su obtencion y aplicaciones.
GB0722077D0 (en) * 2007-11-09 2007-12-19 Smithkline Beecham Corp Compounds
JP5872158B2 (ja) * 2008-03-11 2016-03-01 株式会社 資生堂 皮膚美白方法、並びに、皮膚シミ形成抑制及び/又は除去因子のスクリーニング方法
US8937194B2 (en) * 2008-12-31 2015-01-20 Nitromega Corp. Topical compositions containing nitro fatty acids
US20120157419A1 (en) * 2009-02-02 2012-06-21 Tuvia Gilat Methods and compositions for treating alzheimer's disease
US20160175324A1 (en) * 2013-08-08 2016-06-23 Galderm Therapeutics Ltd. Anti-acne compositions comprising bile acid-fatty acid conjugates
SI3077047T1 (sl) * 2013-12-04 2019-09-30 Galmed Research & Development Ltd. Soli aramchola

Also Published As

Publication number Publication date
JP2016527306A (ja) 2016-09-08
EP3030221A1 (en) 2016-06-15
WO2015019358A1 (en) 2015-02-12
AU2014304078A1 (en) 2016-02-25
US20160175223A1 (en) 2016-06-23
IL227890A0 (en) 2014-01-30
CN105611910A (zh) 2016-05-25
HK1224198A1 (zh) 2017-08-18
EP3030221A4 (en) 2017-02-08
IL243964A0 (en) 2016-04-21

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20190807