CA2914536A1 - Compositions and methods for modulating foxp3 expression - Google Patents

Compositions and methods for modulating foxp3 expression Download PDF

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Publication number
CA2914536A1
CA2914536A1 CA2914536A CA2914536A CA2914536A1 CA 2914536 A1 CA2914536 A1 CA 2914536A1 CA 2914536 A CA2914536 A CA 2914536A CA 2914536 A CA2914536 A CA 2914536A CA 2914536 A1 CA2914536 A1 CA 2914536A1
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CA
Canada
Prior art keywords
foxp3
single stranded
oligonucleotide
stranded oligonucleotide
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2914536A
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English (en)
French (fr)
Inventor
James Barsoum
Mariano SEVERGNINI
James Mcswiggen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Translate Bio Inc
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RaNA Therapeutics Inc
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Filing date
Publication date
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Publication of CA2914536A1 publication Critical patent/CA2914536A1/en
Abandoned legal-status Critical Current

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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  • Pulmonology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
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CA2914536A 2013-06-07 2014-06-06 Compositions and methods for modulating foxp3 expression Abandoned CA2914536A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361832677P 2013-06-07 2013-06-07
US61/832,677 2013-06-07
PCT/US2014/041345 WO2014197826A1 (en) 2013-06-07 2014-06-06 Compositions and methods for modulating foxp3 expression

Publications (1)

Publication Number Publication Date
CA2914536A1 true CA2914536A1 (en) 2014-12-11

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ID=52008624

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2914536A Abandoned CA2914536A1 (en) 2013-06-07 2014-06-06 Compositions and methods for modulating foxp3 expression

Country Status (7)

Country Link
US (1) US20160122760A1 (enExample)
EP (1) EP3004354A4 (enExample)
JP (1) JP2016521556A (enExample)
KR (1) KR20160027968A (enExample)
AU (1) AU2014274730A1 (enExample)
CA (1) CA2914536A1 (enExample)
WO (1) WO2014197826A1 (enExample)

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JP2016531570A (ja) 2013-08-16 2016-10-13 ラナ セラピューティクス インコーポレイテッド ユークロマチン領域を標的とするオリゴヌクレオチド
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TW202028222A (zh) 2018-11-14 2020-08-01 美商Ionis製藥公司 Foxp3表現之調節劑
CN111378622B (zh) * 2018-12-29 2022-12-02 华东师范大学 核酸编码的car-t细胞及其制备方法和应用
JP7557469B2 (ja) * 2019-01-29 2024-09-27 アイオーニス ファーマシューティカルズ， インコーポレーテッド Ａｐｐの発現を低減するための化合物及び方法
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US11866708B2 (en) * 2019-10-22 2024-01-09 Board Of Regents, The University Of Texas System Tailored modulation of gene regulation programs via functional enhancer RNA
WO2021262919A2 (en) 2020-06-26 2021-12-30 The Research Foundation For The State University Of New York 5-halouracil-modified micrornas and their use in the treatment of cancer
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WO2022088342A1 (zh) * 2020-10-28 2022-05-05 苏州吉玛基因股份有限公司 一种靶向FOXP3基因的siRNA及其修饰方法
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