CA2914503A1 - Trans-clomiphene and its analogues as agents that increase bone mineral density - Google Patents
Trans-clomiphene and its analogues as agents that increase bone mineral density Download PDFInfo
- Publication number
- CA2914503A1 CA2914503A1 CA2914503A CA2914503A CA2914503A1 CA 2914503 A1 CA2914503 A1 CA 2914503A1 CA 2914503 A CA2914503 A CA 2914503A CA 2914503 A CA2914503 A CA 2914503A CA 2914503 A1 CA2914503 A1 CA 2914503A1
- Authority
- CA
- Canada
- Prior art keywords
- clomiphene
- trans
- subject
- bone
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361831542P | 2013-06-05 | 2013-06-05 | |
US61/831,542 | 2013-06-05 | ||
PCT/US2014/040704 WO2014197477A1 (en) | 2013-06-05 | 2014-06-03 | Trans-clomiphene and its analogues as agents that increase bone mineral density |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2914503A1 true CA2914503A1 (en) | 2014-11-12 |
Family
ID=52008535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2914503A Abandoned CA2914503A1 (en) | 2013-06-05 | 2014-06-03 | Trans-clomiphene and its analogues as agents that increase bone mineral density |
Country Status (10)
Country | Link |
---|---|
US (1) | US9616034B2 (zh) |
EP (1) | EP3003487A4 (zh) |
JP (1) | JP6417409B2 (zh) |
KR (1) | KR20160016792A (zh) |
CN (1) | CN105473183A (zh) |
AU (1) | AU2014275101B2 (zh) |
CA (1) | CA2914503A1 (zh) |
HK (1) | HK1223318A1 (zh) |
MX (1) | MX2015016093A (zh) |
WO (1) | WO2014197477A1 (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017123577A1 (en) * | 2016-01-12 | 2017-07-20 | Repros Therapeutics Inc. | Trans-clomiphene and progesterone receptor antagonist combination therapy for treating hormone-dependent conditions |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4970237A (en) * | 1987-03-20 | 1990-11-13 | Yale University | Use of clomiphene to increase bone mass in premenopausal women |
CA2597700A1 (en) * | 2005-03-22 | 2006-09-28 | Repros Therapeutics Inc. | Dosing regimes for trans-clomiphene |
WO2006135915A2 (en) | 2005-06-13 | 2006-12-21 | Rigel Pharmaceuticals, Inc. | Methods and compositions for treating degenerative bone disorders |
CA2865234A1 (en) * | 2012-02-29 | 2013-09-06 | Repros Therapeutics Inc. | Combination therapy for treating androgen deficiency |
-
2014
- 2014-06-03 MX MX2015016093A patent/MX2015016093A/es active IP Right Grant
- 2014-06-03 CA CA2914503A patent/CA2914503A1/en not_active Abandoned
- 2014-06-03 KR KR1020157033223A patent/KR20160016792A/ko not_active Application Discontinuation
- 2014-06-03 JP JP2016518412A patent/JP6417409B2/ja not_active Expired - Fee Related
- 2014-06-03 AU AU2014275101A patent/AU2014275101B2/en not_active Ceased
- 2014-06-03 US US14/896,043 patent/US9616034B2/en active Active
- 2014-06-03 CN CN201480032162.1A patent/CN105473183A/zh active Pending
- 2014-06-03 WO PCT/US2014/040704 patent/WO2014197477A1/en active Application Filing
- 2014-06-03 EP EP14807612.8A patent/EP3003487A4/en not_active Withdrawn
-
2016
- 2016-10-04 HK HK16111523.5A patent/HK1223318A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
KR20160016792A (ko) | 2016-02-15 |
WO2014197477A1 (en) | 2014-12-11 |
EP3003487A1 (en) | 2016-04-13 |
US20160128953A1 (en) | 2016-05-12 |
AU2014275101B2 (en) | 2019-10-24 |
US9616034B2 (en) | 2017-04-11 |
EP3003487A4 (en) | 2017-01-25 |
CN105473183A (zh) | 2016-04-06 |
JP6417409B2 (ja) | 2018-11-07 |
AU2014275101A1 (en) | 2015-12-03 |
JP2016520657A (ja) | 2016-07-14 |
HK1223318A1 (zh) | 2017-07-28 |
MX2015016093A (es) | 2016-03-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2826475B1 (en) | Trans-clomiphene for treating diabetes in hypogonadal men | |
DE69814656T2 (de) | Neue verbesserte formulierung zur behandlung der osteoporose | |
JP5910698B2 (ja) | リセドロネート組成物およびその使用方法 | |
JP2005516928A (ja) | 骨異常のためのビスホスホネート液体製剤 | |
HRP950293A2 (en) | Oral liquidalendronate formulations | |
JP2018123168A (ja) | 癌療法における使用のためのトランス−クロミフェン | |
CA2212996A1 (en) | Method of lessening the risk of non-vertebral bone fractures | |
US20080161307A1 (en) | Organic Compounds | |
US20080261924A1 (en) | Method for the treatment of bone disorders | |
TW201500041A (zh) | 用於代謝症候群與第2型糖尿病的反式氯米芬 | |
AU2014275101B2 (en) | Trans-clomiphene and its analogues as agents that increase bone mineral density | |
Tatara et al. | Novel and current approaches to dietary and non-dietary bone metabolism regulation | |
NZ203251A (en) | Pharmaceutical compositions containing 1alpha,25,26-trihydroxycholecalciferol | |
US20130022645A1 (en) | Pharmaceutical formulations of bisphosphonate with enhanced oral bioavailability | |
AU2008314538B2 (en) | Trans-clomiphene for metabolic syndrome | |
WO2002056873A2 (en) | 2-substituted dibenzo[a,e]1,2,3-triazolo[4,5-c][7]annulen-8-ones as growth hormone secretagogues | |
JP2002370981A (ja) | 脳卒中再発防止剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20190530 |
|
FZDE | Discontinued |
Effective date: 20211013 |