CA2909585C - Method for treating dysphagia using a bolus having modified rheological properties - Google Patents

Method for treating dysphagia using a bolus having modified rheological properties Download PDF

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Publication number
CA2909585C
CA2909585C CA2909585A CA2909585A CA2909585C CA 2909585 C CA2909585 C CA 2909585C CA 2909585 A CA2909585 A CA 2909585A CA 2909585 A CA2909585 A CA 2909585A CA 2909585 C CA2909585 C CA 2909585C
Authority
CA
Canada
Prior art keywords
bolus
aspiration
gum
mucilage
swallowing reflex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2909585A
Other languages
English (en)
French (fr)
Other versions
CA2909585A1 (en
Inventor
Adam Burbidge
Jan Engmann
Kala Marie Kaspar
Michael Jedwab
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Original Assignee
Societe des Produits Nestle SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Societe des Produits Nestle SA filed Critical Societe des Produits Nestle SA
Publication of CA2909585A1 publication Critical patent/CA2909585A1/en
Application granted granted Critical
Publication of CA2909585C publication Critical patent/CA2909585C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pediatric Medicine (AREA)
  • Botany (AREA)
  • Physiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Jellies, Jams, And Syrups (AREA)
CA2909585A 2013-05-17 2014-05-16 Method for treating dysphagia using a bolus having modified rheological properties Active CA2909585C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13168363.3 2013-05-17
EP13168363 2013-05-17
PCT/EP2014/060038 WO2014184329A1 (en) 2013-05-17 2014-05-16 Method for treating a swallowing disorder

Publications (2)

Publication Number Publication Date
CA2909585A1 CA2909585A1 (en) 2014-11-20
CA2909585C true CA2909585C (en) 2021-07-13

Family

ID=48482933

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2909585A Active CA2909585C (en) 2013-05-17 2014-05-16 Method for treating dysphagia using a bolus having modified rheological properties

Country Status (9)

Country Link
US (2) US10596108B2 (cg-RX-API-DMAC10.html)
EP (1) EP3010355B1 (cg-RX-API-DMAC10.html)
JP (1) JP2016526028A (cg-RX-API-DMAC10.html)
CN (2) CN105263338A (cg-RX-API-DMAC10.html)
AU (1) AU2014267199B2 (cg-RX-API-DMAC10.html)
BR (1) BR112015027477B1 (cg-RX-API-DMAC10.html)
CA (1) CA2909585C (cg-RX-API-DMAC10.html)
ES (1) ES2904726T3 (cg-RX-API-DMAC10.html)
WO (1) WO2014184329A1 (cg-RX-API-DMAC10.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210329956A1 (en) * 2018-08-30 2021-10-28 N.V. Nutricia Thickened composition for dysphagia patients
EP3893671A1 (en) * 2018-12-13 2021-10-20 Société des Produits Nestlé S.A. Liquid concentrates formulated for dilution into nutritional products to promote safe swallowing for individuals with dysphagia
JP7538796B2 (ja) 2018-12-13 2024-08-22 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 再構成されたときにその伸長特性を維持し、嚥下障害を有する個体による安全な嚥下を助ける粉末状増粘剤
EP4181691A1 (en) * 2020-07-15 2023-05-24 Société des Produits Nestlé S.A. Compositions to promote swallowing safety and efficiency
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
WO2022072718A1 (en) 2020-09-30 2022-04-07 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
WO2022115709A2 (en) * 2020-11-30 2022-06-02 January, Inc. Methods and composition for treating metabolic syndrome
CN112690455A (zh) * 2021-01-15 2021-04-23 山东省食品发酵工业研究设计院 一种基于魔芋多糖的非全营养流食及其制备方法
US20240219281A1 (en) * 2021-03-12 2024-07-04 San-Ei Gen F.F.I., Inc. Method for evaluating texture upon swallowing foods or drinks and method for producing formulation for improving swallowing texture
CN116997322A (zh) * 2021-03-12 2023-11-03 雀巢产品有限公司 促进安全吞咽固体口服剂型(sodf)的液体粘弹性吞咽助剂
EP4119135A1 (fr) * 2021-07-13 2023-01-18 Luxia Scientific Methodes pour reequilibrer la flore intestinale chez les patients souffrant de la maladie de parkinson
CN120501226A (zh) * 2025-07-17 2025-08-19 东莞理工学院 一种通过调控蛋白质静电作用制备易食食品的方法及制品

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002026264A1 (en) * 2000-09-29 2002-04-04 Fuisz Richard C Oral delivery method and composition for solid medications or dietary supplements in the form of solid particles
DE60234038D1 (de) * 2001-08-02 2009-11-26 Simply Thick Llc Verfahren zur herstellung von konzentratverdickungszusammensetzungen
US20040266725A1 (en) * 2001-08-10 2004-12-30 Toray Industries., Inc. Polysaccharide-containing compositions and use thereof
WO2004069179A2 (en) * 2003-01-31 2004-08-19 Simply Thick Llc Improved thickened beverages for dysphagia
JP2005187362A (ja) 2003-12-25 2005-07-14 Ominedo Yakuhin Kogyo Kk 液体ゼリー状経口医薬組成物
JP4693841B2 (ja) 2004-06-01 2011-06-01 プロファジア インコーポレイテッド 嚥下障害者向けに適応させた食品組成物の使用の指標および方法
US20090074940A1 (en) * 2004-11-18 2009-03-19 N.V. Nutricia Thickener composition for dysphagia patients
ES2402753T3 (es) * 2008-02-06 2013-05-08 University Of East Anglia Composición y método para ayudar a la deglución
JP2009256216A (ja) 2008-04-14 2009-11-05 Towa Yakuhin Kk 溶液状態で安定なアムロジピンベシル酸塩内服用液剤
WO2010050541A1 (ja) 2008-10-31 2010-05-06 大日本住友製薬株式会社 咀嚼及び／又は嚥下困難者用食品
GB0906771D0 (en) * 2009-04-20 2009-06-03 Univ Nottingham Agents with antagonistic effects
PH12013501571A1 (en) * 2011-03-01 2013-09-30 Nestec Sa Extensional viscosity to promote safe swallowing of food boluses
JP2012188383A (ja) 2011-03-10 2012-10-04 Towa Yakuhin Kk ドネペジル塩酸塩の内用液剤
EP2790531B1 (en) 2011-12-15 2022-01-19 Société des Produits Nestlé S.A. Cohesive thin liquids to promote safe swallowing in dysphagic patients
US10568831B2 (en) * 2012-06-29 2020-02-25 Wisconsin Alumni Research Foundation Method to enhance swallowing safety and appeal of beverages for treating dysphagia based on rheological and sensory parameters

Also Published As

Publication number Publication date
BR112015027477B1 (pt) 2021-08-03
CN115281333A (zh) 2022-11-04
EP3010355B1 (en) 2021-12-15
EP3010355A1 (en) 2016-04-27
AU2014267199A1 (en) 2015-10-29
US20160081923A1 (en) 2016-03-24
BR112015027477A2 (pt) 2017-07-25
HK1221381A1 (zh) 2017-06-02
US20200188299A1 (en) 2020-06-18
AU2014267199B2 (en) 2019-05-16
CN105263338A (zh) 2016-01-20
US10806699B2 (en) 2020-10-20
ES2904726T3 (es) 2022-04-05
BR112015027477A8 (pt) 2021-03-23
JP2016526028A (ja) 2016-09-01
US10596108B2 (en) 2020-03-24
WO2014184329A1 (en) 2014-11-20
CA2909585A1 (en) 2014-11-20

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