CA2908443A1 - Blastoid, cell line based artificial blastocyst - Google Patents

Blastoid, cell line based artificial blastocyst

Info

Publication number
CA2908443A1
CA2908443A1 CA2908443A CA2908443A CA2908443A1 CA 2908443 A1 CA2908443 A1 CA 2908443A1 CA 2908443 A CA2908443 A CA 2908443A CA 2908443 A CA2908443 A CA 2908443A CA 2908443 A1 CA2908443 A1 CA 2908443A1
Authority
CA
Canada
Prior art keywords
cell
cells
pathway
blastoid
aggregate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2908443A
Other languages
English (en)
French (fr)
Inventor
Nicolas Clement Rivron
Clemens Antoni Van Blitterswijk
Niels Geijsen
Erik Jacob Vrij
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universiteit Maastricht
Koninklijke Nederlandse Akademie van Wetenschappen
Original Assignee
Universiteit Maastricht
Koninklijke Nederlandse Akademie van Wetenschappen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universiteit Maastricht, Koninklijke Nederlandse Akademie van Wetenschappen filed Critical Universiteit Maastricht
Publication of CA2908443A1 publication Critical patent/CA2908443A1/en
Abandoned legal-status Critical Current

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42Gynaecological or obstetrical instruments or methods
    • A61B17/425Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
    • A61B17/435Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for embryo or ova transplantation
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
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    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
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    • C12N2502/02Coculture with; Conditioned medium produced by embryonic cells
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CA2908443A 2013-04-16 2014-04-16 Blastoid, cell line based artificial blastocyst Abandoned CA2908443A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13164018 2013-04-16
EP13164018.7 2013-04-16
PCT/NL2014/050239 WO2014171824A1 (en) 2013-04-16 2014-04-16 Blastoid, cell line based artificial blastocyst

Publications (1)

Publication Number Publication Date
CA2908443A1 true CA2908443A1 (en) 2014-10-23

Family

ID=48092839

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2908443A Abandoned CA2908443A1 (en) 2013-04-16 2014-04-16 Blastoid, cell line based artificial blastocyst

Country Status (6)

Country Link
US (1) US9822336B2 (ja)
EP (1) EP2986711A1 (ja)
JP (1) JP6689498B2 (ja)
CN (1) CN105683363A (ja)
CA (1) CA2908443A1 (ja)
WO (1) WO2014171824A1 (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2908443A1 (en) 2013-04-16 2014-10-23 Koninklijke Nederlandse Akademie Van Wetenschappen Blastoid, cell line based artificial blastocyst
CN111793608B (zh) * 2017-07-28 2022-05-17 杨涛 定向诱导hiPSC分化为神经细胞体系的HS5条件培养基
CN108913654B (zh) * 2018-07-06 2022-08-05 南宁市第二人民医院 Hippo-YAP通路与Wnt通路相互作用在脂肪干细胞细胞谱命运选择中的用途
WO2021067854A1 (en) * 2019-10-03 2021-04-08 Salk Institute For Biological Studies Blastocyst-like structures from extended pluripotent stem cells
WO2021079992A1 (ja) * 2019-10-25 2021-04-29 国立大学法人京都大学 多能性幹細胞からの胚盤胞様構造体の作製法
JP2023550180A (ja) * 2020-11-24 2023-11-30 モナシュ ユニバーシティ 誘導幹細胞
JPWO2022114188A1 (ja) * 2020-11-30 2022-06-02
EP4029932A1 (en) 2021-01-13 2022-07-20 IMBA-Institut für Molekulare Biotechnologie GmbH Blastocyst-like cell aggregate and methods
WO2022152774A1 (en) 2021-01-13 2022-07-21 Imba - Institut Für Molekulare Biotechnologie Gmbh Blastocyst-like cell aggregate and methods
CN112831461B (zh) * 2021-02-26 2023-08-08 澳门大学 一种诱导干细胞分化成中胚层谱系或滋养细胞谱系的方法及药物
CN113201500A (zh) * 2021-05-07 2021-08-03 华夏源细胞工程集团股份有限公司 一种培养iPS细胞的无滋养层培养基
TW202328432A (zh) * 2021-08-26 2023-07-16 清華大學 誘導全能性幹細胞及其製備方法
WO2024030443A1 (en) * 2022-08-01 2024-02-08 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Bovine blastocyst like structures and uses thereof
CN115927168A (zh) * 2023-01-13 2023-04-07 广州国家实验室 全能样细胞高效产生类囊胚的方法及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1802193E (pt) * 2004-10-19 2014-06-23 Regeneron Pharma Método para gerar um murganho homozigótico para uma modificação genética
CA2679109C (en) * 2007-02-23 2016-07-19 Advanced Cell Technology, Inc. Derivation of embryonic stem cells
EP2088191A1 (en) 2008-02-08 2009-08-12 Rheinische Friedrich-Wilhelms-Universität Bonn Induced blastocyst-like structures, methods of production and uses of the same
EP2408903B1 (en) 2009-03-20 2014-08-06 Agency For Science, Technology And Research Culture of pluripotent and multipotent cells on microcarriers
DK2582794T3 (en) * 2010-06-15 2018-05-22 Cellular Dynamics Int Inc GENERATION OF INDUCED PLURIPOTENT STEM CELLS FROM SMALL VOLUMES OF PERIPHERAL BLOOD
US20130074200A2 (en) 2011-01-21 2013-03-21 Cold Spring Harbor Laboratory Inbred c57bl/6 es cells with high developmental capacity
JPWO2012117968A1 (ja) 2011-02-28 2014-07-07 学校法人 岩手医科大学 胚の発生および/または分化を制御する方法
CA2908443A1 (en) 2013-04-16 2014-10-23 Koninklijke Nederlandse Akademie Van Wetenschappen Blastoid, cell line based artificial blastocyst

Also Published As

Publication number Publication date
WO2014171824A1 (en) 2014-10-23
JP6689498B2 (ja) 2020-04-28
US9822336B2 (en) 2017-11-21
CN105683363A (zh) 2016-06-15
US20160060593A1 (en) 2016-03-03
JP2016518831A (ja) 2016-06-30
EP2986711A1 (en) 2016-02-24

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