CA2905739A1 - Recombinant factor viii formulations - Google Patents
Recombinant factor viii formulations Download PDFInfo
- Publication number
- CA2905739A1 CA2905739A1 CA2905739A CA2905739A CA2905739A1 CA 2905739 A1 CA2905739 A1 CA 2905739A1 CA 2905739 A CA2905739 A CA 2905739A CA 2905739 A CA2905739 A CA 2905739A CA 2905739 A1 CA2905739 A1 CA 2905739A1
- Authority
- CA
- Canada
- Prior art keywords
- range
- rfviii
- ppm
- formulation
- fviii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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| US61/869,191 | 2013-08-23 | ||
| PCT/US2014/023357 WO2014150477A1 (en) | 2013-03-15 | 2014-03-11 | Recombinant factor viii formulations |
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| CA2905739A1 true CA2905739A1 (en) | 2014-09-25 |
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| EP3247400A1 (en) * | 2015-01-18 | 2017-11-29 | Biogen MA Inc. | Formulations and screening of biological therapeutic agents |
| CN116949052A (zh) | 2015-11-13 | 2023-10-27 | 武田药品工业株式会社 | 用于血友病a的基因治疗的具有增加的表达的编码重组fviii变体的病毒载体 |
| KR20210034013A (ko) | 2018-07-16 | 2021-03-29 | 박스알타 인코퍼레이티드 | 발현이 증가된 재조합 fviii 변이체들을 인코딩하는 바이러스 벡터를 이용한 혈우병의 유전적 치료법 |
| TWI851647B (zh) | 2019-01-16 | 2024-08-11 | 日商武田藥品工業股份有限公司 | 用於a型血友病基因治療之編碼表現增加之重組fviii變異體的病毒載體 |
| US20220305089A1 (en) * | 2019-08-16 | 2022-09-29 | Octapharma Ag | Stabilizing buffer for factor viii and vwf |
Family Cites Families (9)
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|---|---|---|---|---|
| US5763401A (en) * | 1996-07-12 | 1998-06-09 | Bayer Corporation | Stabilized albumin-free recombinant factor VIII preparation having a low sugar content |
| EP1152450A4 (en) * | 1999-02-01 | 2004-04-14 | Nippon Electric Glass Co | CATHODE RAY TUBE AND METHOD FOR THE PRODUCTION THEREOF |
| ES2435141T3 (es) * | 1999-02-22 | 2013-12-18 | University Of Connecticut | Nuevas formulaciones de factor VIII libres de albúmina |
| EP2110385A1 (en) * | 2001-06-14 | 2009-10-21 | The Scripps Research Institute | Stabilized factor VIII with engineered disulfide bonds |
| GB0207092D0 (en) * | 2002-03-26 | 2002-05-08 | Sod Conseils Rech Applic | Stable pharmaceutical composition containing factor VIII |
| SI1824988T1 (sl) * | 2004-11-12 | 2017-11-30 | Bayer Healthcare Llc | Usmerjena modifikacija FVIII |
| NZ572050A (en) * | 2006-03-31 | 2011-09-30 | Baxter Int | Factor VIII conjugated to polyethylene glycol |
| US20100168018A1 (en) * | 2008-11-07 | 2010-07-01 | Baxter International Inc. | Factor viii formulations |
| US20120121613A1 (en) * | 2009-01-19 | 2012-05-17 | Bayer Healthcare Llc | Protein conjugate having an endopeptidase- cleavable bioprotective moiety |
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2014
- 2014-03-11 PE PE2015002012A patent/PE20160121A1/es not_active Application Discontinuation
- 2014-03-11 CA CA2905739A patent/CA2905739A1/en not_active Abandoned
- 2014-03-11 KR KR1020157029441A patent/KR20150132449A/ko not_active Withdrawn
- 2014-03-11 US US14/774,191 patent/US20160030524A1/en not_active Abandoned
- 2014-03-11 AU AU2014237111A patent/AU2014237111B2/en not_active Ceased
- 2014-03-11 HK HK16101334.5A patent/HK1213273A1/zh unknown
- 2014-03-11 CN CN201480025467.XA patent/CN105209487A/zh active Pending
- 2014-03-11 BR BR112015022730A patent/BR112015022730A2/pt not_active IP Right Cessation
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- 2014-03-11 SG SG10201803999UA patent/SG10201803999UA/en unknown
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- 2014-03-11 EP EP14770228.6A patent/EP2970430A4/en not_active Withdrawn
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- 2014-03-13 TW TW103109012A patent/TW201521761A/zh unknown
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| WO2014150477A1 (en) | 2014-09-25 |
| RU2015144076A (ru) | 2017-04-24 |
| KR20150132449A (ko) | 2015-11-25 |
| ZA201507684B (en) | 2017-06-28 |
| MX2015012905A (es) | 2016-06-16 |
| UY35412A (es) | 2014-10-31 |
| SG10201803999UA (en) | 2018-06-28 |
| JP2016518321A (ja) | 2016-06-23 |
| AU2014237111B2 (en) | 2018-06-21 |
| AU2014237111A1 (en) | 2015-10-08 |
| EP2970430A4 (en) | 2017-01-11 |
| SG11201507618YA (en) | 2015-10-29 |
| PE20160121A1 (es) | 2016-03-03 |
| BR112015022730A2 (pt) | 2017-10-31 |
| US20160030524A1 (en) | 2016-02-04 |
| EP2970430A1 (en) | 2016-01-20 |
| HK1213273A1 (zh) | 2016-06-30 |
| CN105209487A (zh) | 2015-12-30 |
| TW201521761A (zh) | 2015-06-16 |
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