CA2905656C - Cryopreservation of viable human skin substitutes - Google Patents

Cryopreservation of viable human skin substitutes Download PDF

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Publication number
CA2905656C
CA2905656C CA2905656A CA2905656A CA2905656C CA 2905656 C CA2905656 C CA 2905656C CA 2905656 A CA2905656 A CA 2905656A CA 2905656 A CA2905656 A CA 2905656A CA 2905656 C CA2905656 C CA 2905656C
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CA
Canada
Prior art keywords
skin equivalent
cryopreserved
tissues
cryoprotectant
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2905656A
Other languages
English (en)
French (fr)
Other versions
CA2905656A1 (en
Inventor
B. Lynn Allen-Hoffmann
John C. Pirnstill
Kenneth R. Gratz
Allen R. Comer
Original Assignee
Stratatech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stratatech Corp filed Critical Stratatech Corp
Priority to CA3071928A priority Critical patent/CA3071928A1/en
Publication of CA2905656A1 publication Critical patent/CA2905656A1/en
Application granted granted Critical
Publication of CA2905656C publication Critical patent/CA2905656C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
CA2905656A 2013-03-13 2014-03-13 Cryopreservation of viable human skin substitutes Active CA2905656C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3071928A CA3071928A1 (en) 2013-03-13 2014-03-13 Cryopreservation of viable human skin substitutes

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361779661P 2013-03-13 2013-03-13
US61/779,661 2013-03-13
PCT/US2014/025599 WO2014160000A1 (en) 2013-03-13 2014-03-13 Cryopreservation of viable human skin substitutes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3071928A Division CA3071928A1 (en) 2013-03-13 2014-03-13 Cryopreservation of viable human skin substitutes

Publications (2)

Publication Number Publication Date
CA2905656A1 CA2905656A1 (en) 2014-10-02
CA2905656C true CA2905656C (en) 2020-04-14

Family

ID=51527939

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2905656A Active CA2905656C (en) 2013-03-13 2014-03-13 Cryopreservation of viable human skin substitutes
CA3071928A Pending CA3071928A1 (en) 2013-03-13 2014-03-13 Cryopreservation of viable human skin substitutes

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3071928A Pending CA3071928A1 (en) 2013-03-13 2014-03-13 Cryopreservation of viable human skin substitutes

Country Status (10)

Country Link
US (3) US10091983B2 (https=)
EP (3) EP3470018B1 (https=)
JP (2) JP6580028B2 (https=)
AU (4) AU2014244264B2 (https=)
CA (2) CA2905656C (https=)
DK (2) DK2967836T3 (https=)
ES (2) ES2893844T3 (https=)
IL (1) IL241448B (https=)
PT (2) PT2967836T (https=)
WO (1) WO2014160000A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014160000A1 (en) * 2013-03-13 2014-10-02 Stratatech Corporation Cryopreservation of viable human skin substitutes
BR112017000142B1 (pt) 2014-07-09 2021-08-17 Genentech, Inc Métodos para melhorar a recuperação por descongelamento de bancos de células e para congelamento de células cho para armazenamento, grupo de células cho para o congelamento de células de mamíferos, e banco de células
WO2016149254A1 (en) 2015-03-17 2016-09-22 Chimera Bioengineering, Inc. Smart car devices, de car polypeptides, side cars and uses thereof
US11052111B2 (en) * 2015-12-08 2021-07-06 Chimera Bioengineering, Inc. Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses
EP3458077A4 (en) 2016-05-17 2020-04-01 Chimera Bioengineering Inc. METHODS OF MANUFACTURING NEW AREAS OF ANTIGEN BINDING
EP4342978A3 (en) 2016-09-01 2024-07-03 Chimera Bioengineering Inc. Gold optimized car t-cells
CN111989108B (zh) 2018-02-13 2024-07-16 嵌合体生物工程公司 利用rna去稳定元件协调基因表达
EP3843798A1 (en) 2018-08-31 2021-07-07 Wisconsin Alumni Research Foundation Generating arterial endothelial cell-seeded vascular grafts
US20220015354A1 (en) * 2018-11-22 2022-01-20 Vitrafy Life Sciences Pty Ltd Method and apparatus for freezing of biological products
EP4013431A4 (en) 2019-08-18 2024-05-01 Chimera Bioengineering, Inc. Combination therapy with gold controlled transgenes
JP2022549688A (ja) * 2019-09-27 2022-11-28 ストラタテック コーポレーション 急性創傷を治療し、転帰を改善するための方法
CN114836291B (zh) * 2021-02-01 2025-11-21 深圳拜尔洛克生物技术有限公司 生物材料解冻复苏的系统及其方法
WO2022251669A1 (en) * 2021-05-28 2022-12-01 Stratatech Corporation Tissue container systems
JP2024519731A (ja) * 2021-05-28 2024-05-21 ストラタテック コーポレーション 同種異系培養ケラチノサイト製品
US12576135B2 (en) 2021-09-29 2026-03-17 Chimera Bioengineering, Inc. Compositions and methods for anti-TnMUC1 gold CAR t-cells

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485096A (en) 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
IL95429A (en) 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
FI924773L (fi) 1990-04-24 1992-10-21 Mark Eisenberg Kompositionssubstituter av levande hud
IT1248934B (it) 1990-06-01 1995-02-11 Fidia Spa Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle
US5145770A (en) * 1990-06-04 1992-09-08 Biosurface Technology, Inc. Cryopreservation of cultured epithelial sheets
US5518878A (en) 1993-09-15 1996-05-21 Organogenesis Inc. Cryopreservation of cultured skin or cornea equivalents with agitation
US5891617A (en) * 1993-09-15 1999-04-06 Organogenesis Inc. Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing
EP0790767B1 (en) * 1994-11-09 2001-10-10 Celadon Science, LLC Wound repair dressings and methods for their preservation
IT1281870B1 (it) 1995-04-27 1998-03-03 Fidia Advanced Biopolymers Srl Pelle artificiale umana costituita da materiali biocompatibili a base di derivati dell'acido ialuronico
US5693332C1 (en) 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
US5689961A (en) * 1996-01-30 1997-11-25 Organogenesis Inc. Ice seeding apparatus for cryopreservation systems
US5968546A (en) 1997-05-16 1999-10-19 Baur; Marcus Keratinocyte culture from precursor cells
US5989837A (en) 1998-07-13 1999-11-23 Wisconsin Alumni Research Foundation Immortalized human keratinocyte cell line
AU2002246747A1 (en) * 2000-12-27 2002-08-06 Ortec International, Inc. Processes for making cryopreserved composite living constructs and products resulting therefrom
NZ549528A (en) 2001-03-02 2008-04-30 Stratatech Corp Method of making skin equivalents having improved barrier function
US6974697B2 (en) 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
WO2003093418A2 (en) 2002-04-30 2003-11-13 Stratech Corporation Keratinocytes expressing exogenous angiogenic growth factors
EP1546392A4 (en) 2002-08-02 2006-05-24 Stratatech Corp DETECTION OF SPECIFIC DNA FROM SPECIES
US20050186185A1 (en) * 2003-05-30 2005-08-25 Paul Conrad Room temperature storage of organs
PT3100611T (pt) 2003-08-01 2018-12-14 Stratatech Corp Equivalentes de pele humana que expressam polipéptidos exógenos
US7285386B2 (en) * 2003-10-29 2007-10-23 University Of New Mexico, And Educational Institution Of The State Of New Mexico RhPV as a model for HPV-induced cancers
US9163076B2 (en) 2005-03-01 2015-10-20 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
US9295543B2 (en) 2005-03-17 2016-03-29 Stratatech Corporation Skin substitutes with improved purity
KR100803384B1 (ko) * 2007-01-15 2008-02-13 한스바이오메드 주식회사 피부조직의 장기 보관 방법
PT2215212T (pt) 2007-11-14 2017-12-01 Stratatech Corp Armazenamento a frio de equivalentes de pele cultivados de forma organotípica para aplicações clínicas
US8580314B2 (en) 2008-11-04 2013-11-12 Stratatech Corporation Dried and irradiated skin equivalents for ready use
US20100330046A1 (en) 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12
US20130108670A1 (en) * 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating full thickness burn injuries
WO2013062995A1 (en) * 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating deep partial and full thickness wounds and injuries
WO2014160000A1 (en) * 2013-03-13 2014-10-02 Stratatech Corporation Cryopreservation of viable human skin substitutes

Also Published As

Publication number Publication date
DK3470018T3 (da) 2021-10-04
AU2017206148A1 (en) 2017-08-03
ES2705043T3 (es) 2019-03-21
IL241448A0 (en) 2015-11-30
PT2967836T (pt) 2019-01-21
AU2019232795B2 (en) 2021-08-12
IL241448B (en) 2019-02-28
US20220192181A1 (en) 2022-06-23
AU2021261937A1 (en) 2021-12-02
JP2019195344A (ja) 2019-11-14
EP3470018B1 (en) 2021-07-28
AU2014244264B2 (en) 2017-04-20
CA3071928A1 (en) 2014-10-02
JP7220640B2 (ja) 2023-02-10
EP2967836A1 (en) 2016-01-20
EP2967836B1 (en) 2018-10-10
CA2905656A1 (en) 2014-10-02
ES2893844T3 (es) 2022-02-10
US10091983B2 (en) 2018-10-09
PT3470018T (pt) 2021-10-04
AU2019232795A1 (en) 2019-10-10
JP2016512434A (ja) 2016-04-28
DK2967836T3 (en) 2019-01-28
EP3470018A1 (en) 2019-04-17
AU2014244264A1 (en) 2015-10-01
AU2017206148B2 (en) 2019-06-20
JP6580028B2 (ja) 2019-09-25
US20140271583A1 (en) 2014-09-18
EP3900534A1 (en) 2021-10-27
US20190000071A1 (en) 2019-01-03
EP2967836A4 (en) 2016-11-23
US11297829B2 (en) 2022-04-12
WO2014160000A1 (en) 2014-10-02
AU2021261937B2 (en) 2023-11-16

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