CA2903879C - An apparatus for producing nano-bodies - Google Patents
An apparatus for producing nano-bodies Download PDFInfo
- Publication number
- CA2903879C CA2903879C CA2903879A CA2903879A CA2903879C CA 2903879 C CA2903879 C CA 2903879C CA 2903879 A CA2903879 A CA 2903879A CA 2903879 A CA2903879 A CA 2903879A CA 2903879 C CA2903879 C CA 2903879C
- Authority
- CA
- Canada
- Prior art keywords
- flow
- fluid
- hydrofoil
- dispersion medium
- forming
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 108010003723 Single-Domain Antibodies Proteins 0.000 title description 4
- 239000012530 fluid Substances 0.000 claims abstract description 300
- 239000002612 dispersion medium Substances 0.000 claims abstract description 145
- 239000007788 liquid Substances 0.000 claims description 22
- 230000009467 reduction Effects 0.000 claims description 12
- 238000011144 upstream manufacturing Methods 0.000 claims description 11
- 230000007704 transition Effects 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 239000002121 nanofiber Substances 0.000 claims description 4
- 238000005304 joining Methods 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 description 51
- 239000000835 fiber Substances 0.000 description 43
- 239000000243 solution Substances 0.000 description 24
- 230000001133 acceleration Effects 0.000 description 21
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 15
- 239000002904 solvent Substances 0.000 description 15
- 238000000034 method Methods 0.000 description 14
- 230000008859 change Effects 0.000 description 11
- 239000000463 material Substances 0.000 description 10
- 230000008569 process Effects 0.000 description 9
- 238000013467 fragmentation Methods 0.000 description 8
- 238000006062 fragmentation reaction Methods 0.000 description 8
- 238000002347 injection Methods 0.000 description 8
- 239000007924 injection Substances 0.000 description 8
- 239000006185 dispersion Substances 0.000 description 7
- 238000006073 displacement reaction Methods 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 239000012634 fragment Substances 0.000 description 5
- 239000003960 organic solvent Substances 0.000 description 5
- 230000002572 peristaltic effect Effects 0.000 description 5
- 239000002243 precursor Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 description 4
- 239000000654 additive Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- -1 poly(vinyl pyrrolidone) Polymers 0.000 description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 description 4
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 4
- 238000005086 pumping Methods 0.000 description 4
- 238000011021 bench scale process Methods 0.000 description 3
- 239000000178 monomer Substances 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 230000000996 additive effect Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000002071 nanotube Substances 0.000 description 2
- 229920005615 natural polymer Polymers 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 230000002250 progressing effect Effects 0.000 description 2
- 238000010008 shearing Methods 0.000 description 2
- 238000007711 solidification Methods 0.000 description 2
- 230000008023 solidification Effects 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 229920001661 Chitosan Polymers 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 108010022355 Fibroins Proteins 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 229920001730 Moisture cure polyurethane Polymers 0.000 description 1
- 239000004695 Polyether sulfone Substances 0.000 description 1
- 229920002873 Polyethylenimine Polymers 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 239000003125 aqueous solvent Substances 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical compound OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- UHZZMRAGKVHANO-UHFFFAOYSA-M chlormequat chloride Chemical compound [Cl-].C[N+](C)(C)CCCl UHZZMRAGKVHANO-UHFFFAOYSA-M 0.000 description 1
- 239000000701 coagulant Substances 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000007380 fibre production Methods 0.000 description 1
- 238000005188 flotation Methods 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 229920000592 inorganic polymer Polymers 0.000 description 1
- 239000002608 ionic liquid Substances 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000879 optical micrograph Methods 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920000083 poly(allylamine) Polymers 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920006393 polyether sulfone Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000012703 sol-gel precursor Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
Classifications
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/40—Formation of filaments, threads, or the like by applying a shearing force to a dispersion or solution of filament formable polymers, e.g. by stirring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y40/00—Manufacture or treatment of nanostructures
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Nanotechnology (AREA)
- Textile Engineering (AREA)
- Mechanical Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Dispersion Chemistry (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nonwoven Fabrics (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013900814 | 2013-03-06 | ||
| AU2013900814A AU2013900814A0 (en) | 2013-03-06 | Apparatus for forming nanofibres | |
| PCT/AU2014/000204 WO2014134668A1 (en) | 2013-03-06 | 2014-03-05 | An apparatus for producing nano-bodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2903879A1 CA2903879A1 (en) | 2014-09-12 |
| CA2903879C true CA2903879C (en) | 2021-11-09 |
Family
ID=51490481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2903879A Active CA2903879C (en) | 2013-03-06 | 2014-03-05 | An apparatus for producing nano-bodies |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10000865B2 (enExample) |
| EP (1) | EP2964815B1 (enExample) |
| JP (1) | JP6238176B2 (enExample) |
| KR (1) | KR102138083B1 (enExample) |
| CN (1) | CN105705686B (enExample) |
| AU (1) | AU2014225283B2 (enExample) |
| BR (1) | BR112015021475B1 (enExample) |
| CA (1) | CA2903879C (enExample) |
| WO (1) | WO2014134668A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10119214B2 (en) | 2013-07-17 | 2018-11-06 | Sabic Global Technologies B.V. | Force spun sub-micron fiber and applications |
| JP2016528401A (ja) | 2013-08-15 | 2016-09-15 | サビック グローバル テクノロジーズ ベスローテン フェンノートシャップ | 剪断紡糸されたサブマイクロメートル繊維 |
| CN107075733A (zh) * | 2014-10-17 | 2017-08-18 | 沙特基础工业全球技术有限公司 | 制备剪切纺丝纤维的方法和由其制备的纤维 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3485912A (en) * | 1965-02-09 | 1969-12-23 | Dow Chemical Co | Composite article formation |
| US3415920A (en) * | 1965-08-19 | 1968-12-10 | Dow Chemical Co | Multilayer extrusion process |
| US3606636A (en) * | 1967-05-05 | 1971-09-21 | Dow Chemical Co | Extrusion die |
| JPS5242917A (en) * | 1975-10-01 | 1977-04-04 | Basf Ag | Manufactre of fibrils from poly*amideeimide* resin |
| KR800001521B1 (ko) * | 1977-11-28 | 1980-12-20 | 마아빈 터켄 | 필터 시이트 재료의 제조방법 |
| FR2851260B1 (fr) * | 2003-02-19 | 2005-07-01 | Nanoledge | Dispositif pour la fabrication de fibres et/ou de rubans, a partir de particules placees en suspension dans une solution |
| WO2007145989A2 (en) | 2006-06-06 | 2007-12-21 | The Regents Of The University Of California | Apparatus and method for forming fibers |
| CN101089254A (zh) * | 2006-06-16 | 2007-12-19 | 哈尔滨神州惠泽电力自动化有限公司 | 一种磁流体静电纺丝装置 |
| CN101512051A (zh) * | 2006-08-31 | 2009-08-19 | Kx技术有限公司 | 制造纳米纤维的方法 |
| CN101538746B (zh) * | 2008-03-17 | 2010-12-15 | 国家纳米科学中心 | 取向可控静电纺丝纳米聚合物纤维的制备方法 |
| CN101280467B (zh) * | 2008-05-20 | 2010-09-15 | 暨南大学 | 一种壳聚糖基纳米纤维的制备方法与应用 |
| US9217211B2 (en) * | 2009-03-24 | 2015-12-22 | North Carolina State University | Method for fabricating nanofibers |
| JP2012036517A (ja) * | 2010-08-04 | 2012-02-23 | Daicel Corp | セルロース繊維で構成された不織布及び蓄電素子用セパレータ |
| WO2012062931A1 (en) * | 2010-11-13 | 2012-05-18 | Mapper Lithography Ip B.V. | Method for determining a distance between two beamlets in a multi-beamlet exposure apparatus |
| US8647540B2 (en) * | 2011-02-07 | 2014-02-11 | Fiberio Technology Corporation | Apparatuses having outlet elements and methods for the production of microfibers and nanofibers |
| ES2657756T3 (es) * | 2011-10-18 | 2018-03-06 | Heiq Pty Ltd | Proceso de formación de fibra y fibras producidas por medio del proceso |
| WO2013172831A1 (en) * | 2012-05-16 | 2013-11-21 | North Carolina State University | Apparatus and methods for fabricating nanofibers from sheared solutions under continuous flow |
-
2014
- 2014-03-05 CA CA2903879A patent/CA2903879C/en active Active
- 2014-03-05 BR BR112015021475-4A patent/BR112015021475B1/pt active IP Right Grant
- 2014-03-05 KR KR1020157027675A patent/KR102138083B1/ko active Active
- 2014-03-05 WO PCT/AU2014/000204 patent/WO2014134668A1/en not_active Ceased
- 2014-03-05 EP EP14761090.1A patent/EP2964815B1/en active Active
- 2014-03-05 JP JP2015560490A patent/JP6238176B2/ja active Active
- 2014-03-05 US US14/771,362 patent/US10000865B2/en active Active
- 2014-03-05 CN CN201480012489.2A patent/CN105705686B/zh active Active
- 2014-03-05 AU AU2014225283A patent/AU2014225283B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2964815A1 (en) | 2016-01-13 |
| EP2964815B1 (en) | 2018-08-29 |
| HK1215056A1 (en) | 2016-08-12 |
| KR20150133744A (ko) | 2015-11-30 |
| BR112015021475A2 (pt) | 2017-07-18 |
| BR112015021475B1 (pt) | 2022-02-22 |
| CN105705686B (zh) | 2018-01-02 |
| JP6238176B2 (ja) | 2017-11-29 |
| KR102138083B1 (ko) | 2020-07-28 |
| CN105705686A (zh) | 2016-06-22 |
| JP2016513756A (ja) | 2016-05-16 |
| US10000865B2 (en) | 2018-06-19 |
| US20160010242A1 (en) | 2016-01-14 |
| AU2014225283A1 (en) | 2015-09-10 |
| AU2014225283B2 (en) | 2016-01-07 |
| CA2903879A1 (en) | 2014-09-12 |
| WO2014134668A1 (en) | 2014-09-12 |
| EP2964815A4 (en) | 2016-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20190228 |