CA2902157A1 - Nanoparticles for controlled release of anti-biofilm agents - Google Patents

Nanoparticles for controlled release of anti-biofilm agents Download PDF

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Publication number
CA2902157A1
CA2902157A1 CA2902157A CA2902157A CA2902157A1 CA 2902157 A1 CA2902157 A1 CA 2902157A1 CA 2902157 A CA2902157 A CA 2902157A CA 2902157 A CA2902157 A CA 2902157A CA 2902157 A1 CA2902157 A1 CA 2902157A1
Authority
CA
Canada
Prior art keywords
npc
therapeutic agent
biofilm
composition
dmaema
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2902157A
Other languages
English (en)
French (fr)
Inventor
Hyun Koo
Danielle Benoit
Marlise I. Klein
Megan L. Falsetta Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
University of Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Rochester filed Critical University of Rochester
Publication of CA2902157A1 publication Critical patent/CA2902157A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2902157A 2013-02-25 2014-02-25 Nanoparticles for controlled release of anti-biofilm agents Abandoned CA2902157A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361768929P 2013-02-25 2013-02-25
US61/768,929 2013-02-25
PCT/US2014/018211 WO2014130994A1 (en) 2013-02-25 2014-02-25 Nanoparticles for controlled release of anti-biofilm agents

Publications (1)

Publication Number Publication Date
CA2902157A1 true CA2902157A1 (en) 2014-08-28

Family

ID=51391907

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2902157A Abandoned CA2902157A1 (en) 2013-02-25 2014-02-25 Nanoparticles for controlled release of anti-biofilm agents

Country Status (7)

Country Link
US (1) US9566247B2 (enExample)
EP (1) EP2958557B1 (enExample)
JP (1) JP6309980B2 (enExample)
CN (1) CN105142620B (enExample)
AU (1) AU2014218569B2 (enExample)
CA (1) CA2902157A1 (enExample)
WO (1) WO2014130994A1 (enExample)

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GB2463181B (en) 2007-05-14 2013-03-27 Univ New York State Res Found Induction of a physiological dispersion response in bacterial cells in a biofilm
WO2016140845A1 (en) * 2015-03-04 2016-09-09 Dow Global Technologies Llc Copolymers as excipients for effective solubilization of poorly water-soluble substances from solid mixtures
CN113876600B (zh) * 2015-10-21 2024-05-17 密歇根大学董事会 用纳米粒检测和治疗龋和微腔
US20190071706A1 (en) 2016-04-04 2019-03-07 University Of Virginia Patent Foundation Compositions and methods for preventing and treating disease
US20210330599A1 (en) * 2016-08-01 2021-10-28 University Of Rochester Nanoparticles for Controlled Release of Anti-Biofilm Agents and Methods of Use
CN106370636B (zh) * 2016-08-31 2019-02-26 中国科学院新疆生态与地理研究所 一种检测生物膜表面吸附纳米颗粒的方法
CN110621286A (zh) * 2017-02-23 2019-12-27 阿里拉健康波士顿有限责任公司 生态友好型破坏生物膜的抗微生物制剂、其开发及用途
WO2018157367A1 (en) * 2017-03-03 2018-09-07 The Procter & Gamble Company Methods to quantify ion in dental biofilm
JP7136807B2 (ja) * 2017-04-17 2022-09-13 ザ・ユニバーシティ・オブ・シカゴ ヒトの健康及び疾患の治療用途向けの短鎖脂肪酸の腸への送達用ポリマー材料
MX394131B (es) 2017-05-16 2025-03-04 Johnson & Johnson Consumer Inc Partículas revestidas y sus usos.
DE102017130893A1 (de) * 2017-12-21 2019-06-27 Paul Hartmann Ag pH regulierende Wundauflage
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
US12484770B2 (en) 2018-09-06 2025-12-02 Greenmark Biomedical Inc. Dental imaging and/or curing system
CN109091453A (zh) * 2018-09-18 2018-12-28 成都爱睿康美医疗科技有限责任公司 葡萄糖响应性的可注射纳米凝胶及其制备方法和应用
AU2019363848A1 (en) * 2018-10-22 2021-06-03 Endosome Therapeutics, Inc. Nanoparticle encapsulation to target G protein-coupled receptors in endosomes
CN109827814A (zh) * 2019-03-11 2019-05-31 南京大学 一种新型大气颗粒物琼脂采样膜制备及免溶剂提取细胞暴露方法
US12257121B2 (en) * 2019-03-26 2025-03-25 Temple University—Of the Commonwealth System of Higher Education Smart composite with antibiofilm, mineralizing, and antiinfection therapeutic effects
US12195755B2 (en) 2019-05-20 2025-01-14 Brown University Placental lipid bilayer for cell-free molecular interaction studies
DE102019122569A1 (de) 2019-08-22 2021-02-25 Mühlbauer Technology Gmbh Flavonoidderivat
US20210179884A1 (en) 2019-12-17 2021-06-17 Columbia Insurance Company Redox chased suspension bead additives for paints and stains
US20220175812A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
JP2024516108A (ja) 2021-04-07 2024-04-12 バテル・メモリアル・インスティテュート 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術
EP4433037A4 (en) * 2021-11-19 2025-10-15 Univ Michigan Regents NANOPARTICLES TARGETING A BIOFILM TO INCREASE THE ANTI-CARIES EFFECT OF A FLUORIDE
CN119546707A (zh) 2022-07-11 2025-02-28 本杰明·摩尔公司 非离子树脂及其在防污建筑组合物中的用途
CN115671264B (zh) * 2023-01-04 2023-03-07 云南伦扬科技有限公司 一种用于靶向光催化变形链球菌生物膜的级联纳米酶
WO2024226999A1 (en) * 2023-04-28 2024-10-31 Brown University Methods of making and using nanoparticles for treatment of microbial biofilms
CN116570734B (zh) * 2023-07-13 2023-10-13 四川大学华西医院 一种具有靶向功能的核壳壳结构药物胶束及其制备方法
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems
CN118955827B (zh) * 2024-07-31 2025-09-12 安徽农业大学 一种纳米载体及其制备方法和应用

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KR20140070676A (ko) * 2002-09-06 2014-06-10 인설트 테라페틱스, 인코퍼레이티드 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체
WO2005030174A1 (en) 2003-09-23 2005-04-07 Massachusetts Institute Of Technology Ph-triggered microparticles
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CA2730085A1 (en) * 2008-07-09 2010-01-14 Board Of Regents Of The University Of Nebraska Functional micelles for hard tissue targeted delivery of chemicals
EP2335073A4 (en) * 2008-09-02 2012-09-26 Univ Maryland DIAGNOSIS OF BIOFILM IN VIVO INFECTION AND TREATMENT
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Also Published As

Publication number Publication date
JP6309980B2 (ja) 2018-04-11
CN105142620B (zh) 2018-09-28
CN105142620A (zh) 2015-12-09
EP2958557A1 (en) 2015-12-30
AU2014218569A1 (en) 2015-10-15
JP2016509067A (ja) 2016-03-24
US20150374634A1 (en) 2015-12-31
US9566247B2 (en) 2017-02-14
EP2958557A4 (en) 2016-11-30
AU2014218569B2 (en) 2018-10-04
EP2958557B1 (en) 2019-11-27
WO2014130994A1 (en) 2014-08-28

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190205

FZDE Discontinued

Effective date: 20210831

FZDE Discontinued

Effective date: 20210831