CA2899994C - Method to evaluate the tissue targeting of a molecule of interest - Google Patents
Method to evaluate the tissue targeting of a molecule of interest Download PDFInfo
- Publication number
- CA2899994C CA2899994C CA2899994A CA2899994A CA2899994C CA 2899994 C CA2899994 C CA 2899994C CA 2899994 A CA2899994 A CA 2899994A CA 2899994 A CA2899994 A CA 2899994A CA 2899994 C CA2899994 C CA 2899994C
- Authority
- CA
- Canada
- Prior art keywords
- molecule
- interest
- target tissue
- tissue
- distribution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13305211.8 | 2013-02-25 | ||
EP13305211 | 2013-02-25 | ||
PCT/EP2014/053654 WO2014128309A1 (en) | 2013-02-25 | 2014-02-25 | Method to evaluate the tissue targeting of a molecule of interest |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2899994A1 CA2899994A1 (en) | 2014-08-28 |
CA2899994C true CA2899994C (en) | 2022-08-30 |
Family
ID=47998360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2899994A Active CA2899994C (en) | 2013-02-25 | 2014-02-25 | Method to evaluate the tissue targeting of a molecule of interest |
Country Status (7)
Country | Link |
---|---|
US (1) | US9645138B2 (ja) |
EP (1) | EP2959294B1 (ja) |
JP (1) | JP6389479B2 (ja) |
CA (1) | CA2899994C (ja) |
DK (1) | DK2959294T3 (ja) |
ES (1) | ES2693037T3 (ja) |
WO (1) | WO2014128309A1 (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2976076B1 (fr) | 2011-05-31 | 2015-02-27 | Imabiotech | Procede de detection et de quantification d'une molecule cible dans un tissu |
WO2016196312A1 (en) * | 2015-05-29 | 2016-12-08 | Purdue Research Foundation | Methods for analyzing a tissue sample |
JP2017040520A (ja) * | 2015-08-19 | 2017-02-23 | 株式会社島津製作所 | 分析データ表示処理装置及び表示処理プログラム |
ES2781374T3 (es) * | 2015-11-20 | 2020-09-01 | Treat4Life Ab | Método para el análisis de la unión de fármacos en una muestra de tejido |
US10597118B2 (en) | 2016-09-12 | 2020-03-24 | Kai Concepts, LLC | Watercraft device with hydrofoil and electric propeller system |
JPWO2018143357A1 (ja) * | 2017-02-01 | 2019-11-21 | 国立大学法人浜松医科大学 | 標的物質と親和性の高い物質をスクリーニングする方法 |
CN110044997B (zh) * | 2018-01-15 | 2023-08-04 | 中国医学科学院药物研究所 | 一种体内药物的离子强度虚拟校正和定量质谱成像分析方法 |
JP7116937B2 (ja) * | 2018-03-06 | 2022-08-12 | 株式会社Section-Lab | イメージング質量分析に好適な試料作製法及び導電性粘着フィルム |
JP7193114B2 (ja) * | 2018-08-29 | 2022-12-20 | 学校法人同志社 | 胆汁酸サイクルの観察方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5059415A (en) * | 1989-02-21 | 1991-10-22 | The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon Health | Method for diagnostically imaging lesions in the brain inside a blood-brain barrier |
US6689607B2 (en) * | 1997-10-21 | 2004-02-10 | Human Genome Sciences, Inc. | Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2 |
JP4547173B2 (ja) | 2004-03-17 | 2010-09-22 | シスメックス株式会社 | 糖尿病診療支援システム |
EP2322921B1 (en) | 2005-06-07 | 2014-08-06 | Centre National de la Recherche Scientifique (CNRS) | DNTP conjugated to peptide via a UV cleavable linker |
EP2163900A1 (en) | 2008-09-04 | 2010-03-17 | Commissariat A L'energie Atomique | New method of imaging by mass spectrometry and new mass tag associated trityl derivatives |
WO2011073740A1 (en) | 2009-12-15 | 2011-06-23 | Centre National De La Recherche Scientifique (Cnrs) | Matrices for mass spectrometry imaging |
EP2643045A4 (en) * | 2010-11-23 | 2016-01-13 | Presage Biosciences Inc | THERAPEUTIC PROCESSES AND COMPOSITIONS FOR SOLID FORM DELIVERY |
FR2973112B1 (fr) | 2011-03-21 | 2018-05-25 | Imabiotech | Procede de detection et de quantification d'une molecule cible dans un echantillon |
FR2976076B1 (fr) | 2011-05-31 | 2015-02-27 | Imabiotech | Procede de detection et de quantification d'une molecule cible dans un tissu |
EP2767832A1 (en) | 2013-02-18 | 2014-08-20 | Imabiotech | Photo or chemolabile conjugates for molecules detection |
-
2014
- 2014-02-25 WO PCT/EP2014/053654 patent/WO2014128309A1/en active Application Filing
- 2014-02-25 US US14/769,550 patent/US9645138B2/en active Active
- 2014-02-25 DK DK14706597.3T patent/DK2959294T3/en active
- 2014-02-25 ES ES14706597.3T patent/ES2693037T3/es active Active
- 2014-02-25 JP JP2015558493A patent/JP6389479B2/ja active Active
- 2014-02-25 CA CA2899994A patent/CA2899994C/en active Active
- 2014-02-25 EP EP14706597.3A patent/EP2959294B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
ES2693037T3 (es) | 2018-12-07 |
WO2014128309A1 (en) | 2014-08-28 |
EP2959294B1 (en) | 2018-08-08 |
JP2016511402A (ja) | 2016-04-14 |
DK2959294T3 (en) | 2018-11-19 |
US9645138B2 (en) | 2017-05-09 |
US20150377862A1 (en) | 2015-12-31 |
JP6389479B2 (ja) | 2018-09-12 |
EP2959294A1 (en) | 2015-12-30 |
CA2899994A1 (en) | 2014-08-28 |
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CA2899994C (en) | Method to evaluate the tissue targeting of a molecule of interest | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20190129 |
|
EEER | Examination request |
Effective date: 20190129 |