CA2898639A1 - Drive mechanism for drug delivery pumps with integrated status indication - Google Patents
Drive mechanism for drug delivery pumps with integrated status indication Download PDFInfo
- Publication number
- CA2898639A1 CA2898639A1 CA2898639A CA2898639A CA2898639A1 CA 2898639 A1 CA2898639 A1 CA 2898639A1 CA 2898639 A CA2898639 A CA 2898639A CA 2898639 A CA2898639 A CA 2898639A CA 2898639 A1 CA2898639 A1 CA 2898639A1
- Authority
- CA
- Canada
- Prior art keywords
- drive mechanism
- piston
- disposed
- drug
- sleeve assembly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000007246 mechanism Effects 0.000 title claims abstract description 293
- 238000012377 drug delivery Methods 0.000 title description 63
- 239000003814 drug Substances 0.000 claims abstract description 282
- 229940079593 drug Drugs 0.000 claims abstract description 277
- 230000033001 locomotion Effects 0.000 claims abstract description 41
- 230000008859 change Effects 0.000 claims abstract description 7
- 230000006835 compression Effects 0.000 claims description 20
- 238000007906 compression Methods 0.000 claims description 20
- 230000003287 optical effect Effects 0.000 claims description 8
- 230000001960 triggered effect Effects 0.000 claims 2
- 241000282326 Felis catus Species 0.000 claims 1
- 239000012530 fluid Substances 0.000 description 127
- 230000004913 activation Effects 0.000 description 62
- 230000037361 pathway Effects 0.000 description 52
- 238000003780 insertion Methods 0.000 description 51
- 230000037431 insertion Effects 0.000 description 51
- 238000000034 method Methods 0.000 description 20
- 238000013519 translation Methods 0.000 description 18
- 239000000853 adhesive Substances 0.000 description 12
- 230000001070 adhesive effect Effects 0.000 description 12
- 230000005540 biological transmission Effects 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 9
- 238000001802 infusion Methods 0.000 description 8
- 238000002347 injection Methods 0.000 description 8
- 239000007924 injection Substances 0.000 description 8
- 239000007788 liquid Substances 0.000 description 8
- 239000007787 solid Substances 0.000 description 8
- 239000000463 material Substances 0.000 description 7
- 238000011282 treatment Methods 0.000 description 7
- 230000009471 action Effects 0.000 description 6
- 238000006073 displacement reaction Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 230000036512 infertility Effects 0.000 description 6
- 239000004033 plastic Substances 0.000 description 6
- 229920003023 plastic Polymers 0.000 description 6
- 230000000007 visual effect Effects 0.000 description 6
- 230000008878 coupling Effects 0.000 description 5
- 238000010168 coupling process Methods 0.000 description 5
- 238000005859 coupling reaction Methods 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 5
- 229920000089 Cyclic olefin copolymer Polymers 0.000 description 4
- 238000009826 distribution Methods 0.000 description 4
- -1 for example Polymers 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000000717 retained effect Effects 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 239000000806 elastomer Substances 0.000 description 3
- 230000023266 generation of precursor metabolites and energy Effects 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 239000003292 glue Substances 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 230000008054 signal transmission Effects 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 229920001187 thermosetting polymer Polymers 0.000 description 3
- 239000004713 Cyclic olefin copolymer Substances 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000006837 decompression Effects 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 230000000881 depressing effect Effects 0.000 description 2
- 230000000994 depressogenic effect Effects 0.000 description 2
- 238000001647 drug administration Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000008713 feedback mechanism Effects 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
- 230000002028 premature Effects 0.000 description 2
- 229920013730 reactive polymer Polymers 0.000 description 2
- 230000011664 signaling Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004634 thermosetting polymer Substances 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 239000004925 Acrylic resin Substances 0.000 description 1
- 229920000178 Acrylic resin Polymers 0.000 description 1
- 241000796533 Arna Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
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- 230000009849 deactivation Effects 0.000 description 1
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- 230000001934 delay Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- ZUBZATZOEPUUQF-UHFFFAOYSA-N isopropylhexane Natural products CCCCCCC(C)C ZUBZATZOEPUUQF-UHFFFAOYSA-N 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000012744 reinforcing agent Substances 0.000 description 1
- 230000008261 resistance mechanism Effects 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 231100000057 systemic toxicity Toxicity 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361756667P | 2013-01-25 | 2013-01-25 | |
| US61/756,667 | 2013-01-25 | ||
| US201361912642P | 2013-12-06 | 2013-12-06 | |
| US61/912,642 | 2013-12-06 | ||
| PCT/US2014/013005 WO2014116987A1 (en) | 2013-01-25 | 2014-01-24 | Drive mechanism for drug delivery pumps with integrated status indication |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2898639A1 true CA2898639A1 (en) | 2014-07-31 |
Family
ID=50150778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2898639A Abandoned CA2898639A1 (en) | 2013-01-25 | 2014-01-24 | Drive mechanism for drug delivery pumps with integrated status indication |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP3040094A1 (enExample) |
| JP (2) | JP6414783B2 (enExample) |
| CN (1) | CN105431185B (enExample) |
| AU (1) | AU2014209184B2 (enExample) |
| BR (1) | BR112015017717A2 (enExample) |
| CA (1) | CA2898639A1 (enExample) |
| DK (1) | DK2948205T3 (enExample) |
| ES (1) | ES2657274T3 (enExample) |
| IL (1) | IL239943B (enExample) |
| MX (1) | MX359102B (enExample) |
| PT (1) | PT2948205T (enExample) |
| WO (1) | WO2014116987A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX349916B (es) | 2011-09-02 | 2017-08-18 | Unitract Syringe Pty Ltd | Mecanismo accionador para bombas de suministro de fármacos con indicación de status integrada. |
| US9814832B2 (en) | 2011-09-02 | 2017-11-14 | Unl Holdings Llc | Drive mechanism for drug delivery pumps with integrated status indication |
| US9707335B2 (en) | 2011-09-02 | 2017-07-18 | Unitract Syringe Pty Ltd | Drive mechanism for drug delivery pumps with integrated status indication |
| US11173244B2 (en) | 2011-09-02 | 2021-11-16 | Unl Holdings Llc | Drive mechanism for drug delivery pumps with integrated status indication |
| MX352388B (es) | 2012-08-29 | 2017-11-22 | Unitract Syringe Pty Ltd | Mecanismos impulsores de administración controlada de velocidad variable para bombas de administración de fármacos. |
| GB2526948A (en) | 2012-12-27 | 2015-12-09 | Kaleo Inc | Systems for locating and interacting with medicament delivery devices |
| US10773024B2 (en) | 2016-06-09 | 2020-09-15 | Becton, Dickinson And Company | Drive assembly for drug delivery system |
| US10603445B2 (en) * | 2016-06-09 | 2020-03-31 | Becton, Dickinson And Company | Needle actuator assembly for drug delivery system |
| EP3519016A1 (en) * | 2016-09-27 | 2019-08-07 | Sanofi-Aventis Deutschland GmbH | A medicament delivery device |
| KR102354959B1 (ko) | 2016-12-28 | 2022-01-24 | 제넨테크, 인크. | 주사 모니터링 장치 |
| WO2018136413A2 (en) | 2017-01-17 | 2018-07-26 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and event detection |
| IL270619B2 (en) * | 2017-06-06 | 2024-03-01 | Unl Holdings Llc | Full-finish carriers for drug containers |
| US11779708B2 (en) | 2017-12-22 | 2023-10-10 | Sanofi | Drug delivery device |
| WO2020018433A1 (en) | 2018-07-16 | 2020-01-23 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and compliance detection |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4755172A (en) * | 1987-06-30 | 1988-07-05 | Baldwin Brian E | Syringe holder/driver and syringe arrangement and syringe/holder driver therefor |
| JPH062677Y2 (ja) * | 1991-08-19 | 1994-01-26 | 義幸 井河 | 注射針を外して収納する注射針収納具 |
| WO1997034651A1 (en) * | 1996-03-19 | 1997-09-25 | Mcphee Charles J | Platen pump |
| JPWO2003057286A1 (ja) * | 2001-12-13 | 2005-05-12 | 松下電器産業株式会社 | 医療用投与器具 |
| US20050033232A1 (en) * | 2003-08-05 | 2005-02-10 | Kriesel Marshall S. | Infusion apparatus with modulated flow control |
| TWI498137B (zh) * | 2006-06-30 | 2015-09-01 | Abbvie Biotechnology Ltd | 自動注射裝置 |
| EP2162170B1 (en) * | 2007-07-06 | 2011-03-16 | SHL Group AB | One shot injector with dual springs |
| GB2463034B (en) * | 2008-08-28 | 2012-11-07 | Owen Mumford Ltd | Autoinjection devices |
| CA2757136A1 (en) * | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Improvements in and relating to a medicament delivery devices |
| KR101857300B1 (ko) * | 2009-10-13 | 2018-05-11 | 발레리타스 인코포레이티드 | 유체 전달 장치 |
| EP3824925B1 (en) * | 2010-05-20 | 2023-07-05 | Becton, Dickinson and Company | Drug delivery device |
| WO2012032411A2 (en) * | 2010-09-07 | 2012-03-15 | Tecpharma Licensing Ag | Automatic injection device |
| EP2537546A1 (en) * | 2011-06-21 | 2012-12-26 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device with dose control mechanism |
| MX349916B (es) * | 2011-09-02 | 2017-08-18 | Unitract Syringe Pty Ltd | Mecanismo accionador para bombas de suministro de fármacos con indicación de status integrada. |
| EP2838586B1 (en) * | 2012-04-20 | 2016-02-17 | Novo Nordisk A/S | Medical injection device comprising a secondary safety limiter |
| MX352388B (es) * | 2012-08-29 | 2017-11-22 | Unitract Syringe Pty Ltd | Mecanismos impulsores de administración controlada de velocidad variable para bombas de administración de fármacos. |
-
2014
- 2014-01-24 AU AU2014209184A patent/AU2014209184B2/en not_active Ceased
- 2014-01-24 MX MX2015009530A patent/MX359102B/es active IP Right Grant
- 2014-01-24 CA CA2898639A patent/CA2898639A1/en not_active Abandoned
- 2014-01-24 WO PCT/US2014/013005 patent/WO2014116987A1/en not_active Ceased
- 2014-01-24 JP JP2015555355A patent/JP6414783B2/ja not_active Expired - Fee Related
- 2014-01-24 ES ES14705619.6T patent/ES2657274T3/es active Active
- 2014-01-24 EP EP16153193.4A patent/EP3040094A1/en not_active Withdrawn
- 2014-01-24 EP EP14705619.6A patent/EP2948205B1/en active Active
- 2014-01-24 BR BR112015017717A patent/BR112015017717A2/pt active Search and Examination
- 2014-01-24 DK DK14705619.6T patent/DK2948205T3/en active
- 2014-01-24 PT PT147056196T patent/PT2948205T/pt unknown
- 2014-01-24 CN CN201480006140.8A patent/CN105431185B/zh not_active Expired - Fee Related
-
2015
- 2015-07-15 IL IL239943A patent/IL239943B/en not_active IP Right Cessation
-
2018
- 2018-09-21 JP JP2018176795A patent/JP2018196811A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014116987A1 (en) | 2014-07-31 |
| EP2948205A1 (en) | 2015-12-02 |
| JP2016504164A (ja) | 2016-02-12 |
| AU2014209184A1 (en) | 2015-09-03 |
| AU2014209184B2 (en) | 2018-08-02 |
| PT2948205T (pt) | 2018-02-02 |
| HK1217923A1 (en) | 2017-01-27 |
| IL239943B (en) | 2020-02-27 |
| JP6414783B2 (ja) | 2018-10-31 |
| MX359102B (es) | 2018-09-14 |
| BR112015017717A2 (pt) | 2017-07-11 |
| CN105431185B (zh) | 2019-02-19 |
| DK2948205T3 (en) | 2018-02-05 |
| CN105431185A (zh) | 2016-03-23 |
| EP2948205B1 (en) | 2017-11-01 |
| ES2657274T3 (es) | 2018-03-02 |
| MX2015009530A (es) | 2016-02-05 |
| IL239943A0 (en) | 2015-08-31 |
| JP2018196811A (ja) | 2018-12-13 |
| EP3040094A1 (en) | 2016-07-06 |
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| US11173244B2 (en) | Drive mechanism for drug delivery pumps with integrated status indication | |
| EP2948205B1 (en) | Drive mechanism for drug delivery pumps with integrated status indication | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20181207 |
|
| FZDE | Discontinued |
Effective date: 20210309 |