CA2896866A1 - Lyophilized fibrin sealant for high volume hemorrhage - Google Patents

Lyophilized fibrin sealant for high volume hemorrhage Download PDF

Info

Publication number
CA2896866A1
CA2896866A1 CA2896866A CA2896866A CA2896866A1 CA 2896866 A1 CA2896866 A1 CA 2896866A1 CA 2896866 A CA2896866 A CA 2896866A CA 2896866 A CA2896866 A CA 2896866A CA 2896866 A1 CA2896866 A1 CA 2896866A1
Authority
CA
Canada
Prior art keywords
fibrin
composition
clotblock
bleeding
lyophilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2896866A
Other languages
English (en)
French (fr)
Inventor
George David Falus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/731,126 external-priority patent/US8741845B1/en
Application filed by Individual filed Critical Individual
Publication of CA2896866A1 publication Critical patent/CA2896866A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0042—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/042—Force radial
    • F04C2270/0421—Controlled or regulated
CA2896866A 2012-12-31 2013-12-28 Lyophilized fibrin sealant for high volume hemorrhage Abandoned CA2896866A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/731,126 US8741845B1 (en) 2009-06-18 2012-12-31 Lyophilized fibrin sealant for high volume hemorrhage
US13/731,126 2012-12-31
PCT/US2013/078152 WO2014106136A1 (en) 2012-12-31 2013-12-28 Lyophilized fibrin sealant for high volume hemorrhage

Publications (1)

Publication Number Publication Date
CA2896866A1 true CA2896866A1 (en) 2014-07-03

Family

ID=51022102

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2896866A Abandoned CA2896866A1 (en) 2012-12-31 2013-12-28 Lyophilized fibrin sealant for high volume hemorrhage

Country Status (6)

Country Link
EP (1) EP2938275A1 (zh)
JP (1) JP2016507279A (zh)
CN (1) CN105007841A (zh)
AU (1) AU2013370223A1 (zh)
CA (1) CA2896866A1 (zh)
WO (1) WO2014106136A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020501543A (ja) 2016-12-07 2020-01-23 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 網膜色素上皮移植のためのフィブリン支持体を用いた方法及び材料
MX2019014503A (es) * 2017-06-05 2020-01-23 Mayo Found Medical Education & Res Metodos y materiales para cultivar, proliferar, y diferenciar celulas madre.
CN114366847B (zh) * 2022-01-21 2022-08-12 四川大学华西医院 一种快速止血冻干纤维气凝胶及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
GB9711927D0 (en) * 1997-06-09 1997-08-06 Bristol Myers Squibb Co Compositions useful as fibrin sealants
JP2001511431A (ja) * 1997-07-28 2001-08-14 フィブロジェン， インコーポレイテッド Ｉ型およびｉｉｉ型コラーゲン接着剤組成物
US20020064517A1 (en) * 1998-04-30 2002-05-30 Stewart A. Cederholm-Williams Fibrin sealant as a transfection/transformation vehicle for gene therapy
US6056970A (en) * 1998-05-07 2000-05-02 Genzyme Corporation Compositions comprising hemostatic compounds and bioabsorbable polymers
DE19851334C2 (de) * 1998-11-06 2000-09-28 Aventis Behring Gmbh Flexible Wundauflage auf Fibrinbasis und Verfahren zu ihrer Herstellung
CN1485090A (zh) * 2002-09-29 2004-03-31 罗晓浔 新型纤维蛋白封闭剂及应用
WO2004067704A2 (en) * 2003-01-30 2004-08-12 Prochon Biotech Ltd. Freeze-dried fibrin matrices and methods for preparation thereof
CN1454667A (zh) * 2003-05-07 2003-11-12 徐振彪 使用方便的纤维蛋白封闭剂
CN100522248C (zh) * 2005-06-28 2009-08-05 吴昌琳 一种稳定的液态复合纤维蛋白封闭剂及制备
CN101214391B (zh) * 2007-12-27 2010-05-19 广州倍绣生物技术有限公司 一种高效生物胶封闭剂及其应用
CN101371921B (zh) * 2008-10-08 2013-02-13 余美伦 一种速溶冻干纤维蛋白原和凝血酶制剂组合物、制备方法及其用途
CN101797377B (zh) * 2009-02-11 2012-01-25 北京赛升药业股份有限公司 纤维蛋白封闭剂及其制备方法
US20100256671A1 (en) * 2009-04-07 2010-10-07 Biomedica Management Corporation Tissue sealant for use in noncompressible hemorrhage
US8314211B2 (en) * 2009-04-07 2012-11-20 George Falus Tissue sealant for use in non compressible hemorrhage
US8367802B2 (en) * 2009-06-18 2013-02-05 Biomedica Management Corporation Method to produce fibrin monomer in acid media for use as tissue sealant
CN102258770A (zh) * 2010-05-26 2011-11-30 上海利康瑞生物工程有限公司 一种安全高效的冻干纤维蛋白封闭剂及其制备方法
US20120015022A1 (en) * 2010-07-13 2012-01-19 Speechswitch, Inc. Biodegradable wound care products with biocompatible artificial skin treatment

Also Published As

Publication number Publication date
WO2014106136A1 (en) 2014-07-03
AU2013370223A1 (en) 2015-08-06
EP2938275A1 (en) 2015-11-04
CN105007841A (zh) 2015-10-28
JP2016507279A (ja) 2016-03-10

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Legal Events

Date Code Title Description
FZDE Dead

Effective date: 20161229