CA2892147A1 - Cd44v6-derived peptides for treating metastasizing cancers - Google Patents

Cd44v6-derived peptides for treating metastasizing cancers Download PDF

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Publication number
CA2892147A1
CA2892147A1 CA2892147A CA2892147A CA2892147A1 CA 2892147 A1 CA2892147 A1 CA 2892147A1 CA 2892147 A CA2892147 A CA 2892147A CA 2892147 A CA2892147 A CA 2892147A CA 2892147 A1 CA2892147 A1 CA 2892147A1
Authority
CA
Canada
Prior art keywords
group
amino acids
cancer
peptide
side chains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2892147A
Other languages
English (en)
French (fr)
Inventor
Veronique Orian-Rousseau
Alexandra Matzke
Helmut Ponta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AMCURE GmbH
Original Assignee
AMCURE GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AMCURE GmbH filed Critical AMCURE GmbH
Publication of CA2892147A1 publication Critical patent/CA2892147A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2892147A 2012-11-21 2013-11-21 Cd44v6-derived peptides for treating metastasizing cancers Abandoned CA2892147A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1220889.8 2012-11-21
GBGB1220889.8A GB201220889D0 (en) 2012-11-21 2012-11-21 CD44v6-derived peptides for treating metastasizing cancers
PCT/EP2013/074404 WO2014079943A1 (en) 2012-11-21 2013-11-21 Cd44v6-derived peptides for treating metastasizing cancers

Publications (1)

Publication Number Publication Date
CA2892147A1 true CA2892147A1 (en) 2014-05-30

Family

ID=47521460

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2892147A Abandoned CA2892147A1 (en) 2012-11-21 2013-11-21 Cd44v6-derived peptides for treating metastasizing cancers

Country Status (13)

Country Link
US (1) US9593146B2 (enExample)
EP (1) EP2922563B1 (enExample)
JP (1) JP2016501858A (enExample)
AU (1) AU2013349703B2 (enExample)
CA (1) CA2892147A1 (enExample)
DK (1) DK2922563T3 (enExample)
ES (1) ES2765037T3 (enExample)
GB (1) GB201220889D0 (enExample)
HU (1) HUE047126T2 (enExample)
IL (1) IL238606B (enExample)
LT (1) LT2922563T (enExample)
SI (1) SI2922563T1 (enExample)
WO (1) WO2014079943A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201421647D0 (en) 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
EP3466963A1 (en) * 2017-10-05 2019-04-10 Suigeneris Farmacosmetics, S.L. Anticancer peptides and uses thereof
KR102194025B1 (ko) 2017-12-15 2020-12-22 경북대학교 산학협력단 CD44v6에 결합하는 펩타이드 및 이의 용도
JP7510874B2 (ja) 2017-12-22 2024-07-04 ヒプラ シエンティフィック エセ.エレ.ウ. マイコプラズマ及びブタサーコウイルスに対する皮内混合ワクチン
EP4464714A1 (en) 2023-05-19 2024-11-20 Karlsruher Institut für Technologie Screening method for cell-repelling peptides

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696229A (en) 1995-03-16 1997-12-09 The University Of Virginia Patent Foundation Polypeptide with laminin cell adhesion and morphogenesis activity
DE19540515C1 (de) * 1995-10-31 1997-02-06 Boehringer Ingelheim Int Tumortherapie durch adoptiven Transfer CD44v-spezifischer zytotoxischer T-Lymphozyten
EP1258255A1 (en) * 2001-05-18 2002-11-20 Boehringer Ingelheim International GmbH Conjugates of an antibody to CD44 and a maytansinoid
JP2003089700A (ja) 2001-09-18 2003-03-28 Life Science Management:Kk ペプチド
EP1417974A1 (en) * 2002-11-08 2004-05-12 Boehringer Ingelheim International GmbH Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and radiotherapy
WO2005065709A2 (de) 2003-12-24 2005-07-21 Boehringer Ingelheim International Gmbh Gefriergetrocknete formulierung von antikörperkonjugaten
DE602004027255D1 (de) * 2004-10-14 2010-07-01 Karlsruher Inst Technologie Peptidische Verbindungen und deren Ableitungen für die Behandllung von menschlichen Krankheiten durch Hemmung der Signalübertragung über Wachstumfaktoren
EP2218457B1 (en) * 2009-02-16 2011-09-07 Karlsruher Institut für Technologie CD44v6 peptides as inhibitors of bacterial infections
EP2266593A1 (en) * 2009-06-24 2010-12-29 Karlsruher Institut für Technologie Use of CD44v6 in the treatment of ophthalmic diseases
WO2011022335A1 (en) 2009-08-21 2011-02-24 Mount Sinai School Of Medicine Of New York University Methods of using cd44 fusion proteins to treat cancer

Also Published As

Publication number Publication date
ES2765037T3 (es) 2020-06-05
IL238606A0 (en) 2015-06-30
US20150183826A1 (en) 2015-07-02
AU2013349703B2 (en) 2016-12-22
JP2016501858A (ja) 2016-01-21
DK2922563T3 (da) 2020-01-20
EP2922563B1 (en) 2019-10-30
HUE047126T2 (hu) 2020-04-28
WO2014079943A1 (en) 2014-05-30
EP2922563A1 (en) 2015-09-30
SI2922563T1 (sl) 2020-04-30
LT2922563T (lt) 2020-03-25
US9593146B2 (en) 2017-03-14
IL238606B (en) 2019-07-31
GB201220889D0 (en) 2013-01-02
AU2013349703A1 (en) 2015-07-09

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150521

FZDE Discontinued

Effective date: 20200107