CA2890419C - Drug delivery device for the treatment of patients with respiratory diseases - Google Patents

Drug delivery device for the treatment of patients with respiratory diseases Download PDF

Info

Publication number
CA2890419C
CA2890419C CA2890419A CA2890419A CA2890419C CA 2890419 C CA2890419 C CA 2890419C CA 2890419 A CA2890419 A CA 2890419A CA 2890419 A CA2890419 A CA 2890419A CA 2890419 C CA2890419 C CA 2890419C
Authority
CA
Canada
Prior art keywords
inhalation
powdered medicament
inhaler
dosing recess
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2890419A
Other languages
English (en)
French (fr)
Other versions
CA2890419A1 (en
Inventor
Mark Parry-Billings
Mario Scuri
Maria Chiara TAVERNA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Publication of CA2890419A1 publication Critical patent/CA2890419A1/en
Application granted granted Critical
Publication of CA2890419C publication Critical patent/CA2890419C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0075—Mechanical counters having a display or indicator on a disc
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/062—Desiccants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3375—Acoustical, e.g. ultrasonic, measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3553—Range remote, e.g. between patient's home and doctor's office
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3584—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using modem, internet or Bluetooth®
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emergency Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Steroid Compounds (AREA)
CA2890419A 2012-11-07 2013-11-05 Drug delivery device for the treatment of patients with respiratory diseases Active CA2890419C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12191562.3 2012-11-07
EP12191562 2012-11-07
PCT/EP2013/072988 WO2014072268A1 (en) 2012-11-07 2013-11-05 Drug delivery device for the treatment of patients with respiratory diseases

Publications (2)

Publication Number Publication Date
CA2890419A1 CA2890419A1 (en) 2014-05-15
CA2890419C true CA2890419C (en) 2021-01-12

Family

ID=47172473

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2890419A Active CA2890419C (en) 2012-11-07 2013-11-05 Drug delivery device for the treatment of patients with respiratory diseases

Country Status (10)

Country Link
US (1) US11052202B2 (enExample)
EP (2) EP3679972B1 (enExample)
KR (1) KR102239756B1 (enExample)
CN (2) CN111214738A (enExample)
AR (1) AR093382A1 (enExample)
CA (1) CA2890419C (enExample)
HK (1) HK1208830A1 (enExample)
IN (1) IN2015DN03811A (enExample)
RU (1) RU2648849C2 (enExample)
WO (1) WO2014072268A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA034279B1 (ru) * 2013-12-23 2020-01-24 Гленмарк Фармасьютикалс Лтд Ингалятор сухого порошка
US10456536B2 (en) * 2014-03-25 2019-10-29 Koninklijke Philips N.V. Inhaler with two microphones for detection of inhalation flow
US10737042B2 (en) * 2014-08-26 2020-08-11 Michael Edward Breede Thermal modulation of an inhalable medicament
US10058661B2 (en) 2014-12-04 2018-08-28 Norton (Waterford) Limited Inhalation monitoring system and method
SE539111C2 (en) * 2015-06-03 2017-04-11 Iconovo Ab Single dose dry powder inhaler
ES2745552T3 (es) 2015-07-20 2020-03-02 Pearl Therapeutics Inc Sistemas de administración de aerosol
GB2553281A (en) * 2016-08-22 2018-03-07 Medituner Ab Method and system for selecting inhaler
JP7242630B2 (ja) * 2017-07-21 2023-03-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ及びリザーバ
GB2570439A (en) * 2017-12-13 2019-07-31 British American Tobacco Investments Ltd Method and apparatus for analysing user interaction
WO2020088984A1 (en) * 2018-10-30 2020-05-07 Chiesi Farmaceutici S.P.A. Apparatus to administer drugs to mechanically ventilated patients
BR112022009973A2 (pt) 2019-11-28 2022-08-09 Chiesi Farm Spa Módulo eletrônico para um inalador e montagem de inalador que compreende o módulo eletrônico
BR112022009952A8 (pt) * 2019-11-28 2023-09-26 Chiesi Farm Spa Montagem de inalador de pó
FR3121361A1 (fr) * 2021-04-01 2022-10-07 Hephaï Détection de la synchronisation entre l’actionnement d’un inhalateur-doseur sous pression et l’inspiration d’un patient
WO2024028388A1 (en) * 2022-08-03 2024-02-08 Chiesi Farmaceutici S.P.A. Dry powder inhaler
WO2026136309A1 (en) * 2024-12-20 2026-06-25 Nypro Inc. Dry powder inhaler with integrated desiccant

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3555192A (en) * 1969-07-08 1971-01-12 Nasa Audio signal processor
CA2123909C (en) * 1991-12-18 2002-10-01 Christer Carl Gustav Carling New combination of formoterol and budesonide
US6152130A (en) 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
PT1158958E (pt) * 1999-03-05 2007-08-13 Chiesi Farma Spa ''composições farmacêuticas em pó, melhoradas, para inalação''
US6858199B1 (en) * 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
PT1386630E (pt) * 2002-07-31 2006-09-29 Chiesi Farma Spa Inalador em po
SE0302665D0 (sv) * 2003-10-07 2003-10-07 Astrazeneca Ab Novel Process
GB2398065A (en) 2003-10-16 2004-08-11 Bespak Plc Dispensing apparatus
WO2007101438A1 (en) * 2006-03-07 2007-09-13 Bang & Olufsen Medicom A/S Acoustic inhaler flow measurement
RU2427392C2 (ru) 2006-04-05 2011-08-27 Майкродоуз Терапьютикс, Инк. Ингаляционное устройство с регулируемой дозой
EP1982709A1 (en) * 2007-04-19 2008-10-22 CHIESI FARMACEUTICI S.p.A. Use of a composition comprising formoterol and beclomethasone dipropionate for the prevention or treatment of an acute condition of asthma
GB2451833A (en) 2007-08-13 2009-02-18 Bespak Plc Electrically actuated dose counter for dispensing apparatus
DE102007058112A1 (de) 2007-12-03 2009-06-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Wirkstofftablette
US8721632B2 (en) * 2008-09-09 2014-05-13 Tsunami Medtech, Llc Methods for delivering energy into a target tissue of a body
MX2011006219A (es) * 2008-12-11 2011-06-28 Respivert Ltd Inhibidores de la proteina cinasa activada por el mitogeno p38.
WO2011038872A1 (en) * 2009-10-02 2011-04-07 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol formulations of formoterol and beclometasone dipropionate
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
RU2580312C2 (ru) * 2010-04-21 2016-04-10 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Способ получения частиц с пониженным электростатическим зарядом
GB201006901D0 (en) * 2010-04-26 2010-06-09 Sagentia Ltd Device for monitoring status and use of an inhalation or nasal drug delivery device

Also Published As

Publication number Publication date
WO2014072268A1 (en) 2014-05-15
BR112015009149A2 (pt) 2017-07-04
HK1208830A1 (en) 2016-03-18
US20140158126A1 (en) 2014-06-12
AR093382A1 (es) 2015-06-03
RU2648849C2 (ru) 2018-03-28
EP3679972A1 (en) 2020-07-15
US11052202B2 (en) 2021-07-06
KR20150083849A (ko) 2015-07-20
CA2890419A1 (en) 2014-05-15
CN111214738A (zh) 2020-06-02
IN2015DN03811A (enExample) 2015-10-02
CN104780963A (zh) 2015-07-15
RU2015116757A (ru) 2016-12-27
KR102239756B1 (ko) 2021-04-14
EP2916897A1 (en) 2015-09-16
EP3679972B1 (en) 2023-04-05

Similar Documents

Publication Publication Date Title
EP3679972B1 (en) Drug delivery device for the treatment of patients with respiratory diseases
AU2021200443B2 (en) Inhalation monitoring system and method
Al-Showair et al. Can all patients with COPD use the correct inhalation flow with all inhalers and does training help?
US20230302238A1 (en) Inhaler system
EP4291273B1 (en) Inhaler system
HK40019484A (en) Drug delivery device for the treatment of patients with respiratory diseases
Bhuiyan et al. Metered dose inhaler (MDI) versus dry powder inhaler (DPI): Patient’s compliance variation in asthma medication at rural Bangladesh perspective
US20240108826A1 (en) Inhaler system
BR112015009149B1 (pt) Inalador de pó seco
EP4678170A1 (en) A fixed-dose dry powder inhalation formulation of fluticasone propionate and albuterol sulfate for the treatment of asthma
WO2026013023A1 (en) A fixed-dose dry powder inhalation formulation of fluticasone propionate and albuterol sulfate for the treatment of asthma
Col et al. Salbutamol powder, administered via a multidose and a single-dose powder inhaler, in the prevention of exercise-induced asthma in children
HK1237683B (en) Inhalation monitoring system
HK1237683A1 (en) Inhalation monitoring system

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20181105

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 11TH ANNIV.) - STANDARD

Year of fee payment: 11

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20241101

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20241101