CA2887072C - System and method for providing patient-specific dosing as a function of mathematical models - Google Patents
System and method for providing patient-specific dosing as a function of mathematical models Download PDFInfo
- Publication number
- CA2887072C CA2887072C CA2887072A CA2887072A CA2887072C CA 2887072 C CA2887072 C CA 2887072C CA 2887072 A CA2887072 A CA 2887072A CA 2887072 A CA2887072 A CA 2887072A CA 2887072 C CA2887072 C CA 2887072C
- Authority
- CA
- Canada
- Prior art keywords
- patient
- specific
- model
- dosing regimen
- response
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N7/00—Computing arrangements based on specific mathematical models
- G06N7/01—Probabilistic graphical models, e.g. probabilistic networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Data Mining & Analysis (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Databases & Information Systems (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Algebra (AREA)
- Probability & Statistics with Applications (AREA)
- General Engineering & Computer Science (AREA)
- Computing Systems (AREA)
- Pure & Applied Mathematics (AREA)
- Mathematical Optimization (AREA)
- Mathematical Analysis (AREA)
- Evolutionary Computation (AREA)
- Computational Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mathematical Physics (AREA)
- Software Systems (AREA)
- Artificial Intelligence (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261710330P | 2012-10-05 | 2012-10-05 | |
| US61/710,330 | 2012-10-05 | ||
| PCT/US2013/063691 WO2014055978A1 (en) | 2012-10-05 | 2013-10-07 | System and method for providing patient-specific dosing as a function of mathematical models |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2887072A1 CA2887072A1 (en) | 2014-04-10 |
| CA2887072C true CA2887072C (en) | 2024-04-16 |
Family
ID=50433375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2887072A Active CA2887072C (en) | 2012-10-05 | 2013-10-07 | System and method for providing patient-specific dosing as a function of mathematical models |
Country Status (9)
| Country | Link |
|---|---|
| US (6) | US10083400B2 (enExample) |
| EP (2) | EP2904388B1 (enExample) |
| JP (5) | JP6412499B2 (enExample) |
| KR (3) | KR102370479B1 (enExample) |
| AU (4) | AU2013326801A1 (enExample) |
| CA (1) | CA2887072C (enExample) |
| IL (3) | IL238115B (enExample) |
| SG (2) | SG10201907682RA (enExample) |
| WO (1) | WO2014055978A1 (enExample) |
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| EP2904388B1 (en) | 2012-10-05 | 2023-06-07 | Diane R. Mould | System and method for providing patient-specific dosing as a function of mathematical models |
| US9238144B2 (en) * | 2013-03-14 | 2016-01-19 | Neuropace, Inc. | Optimizing data retrieval from an active implantable medical device |
| EP3082848B1 (en) * | 2013-12-06 | 2023-10-18 | Bioverativ Therapeutics Inc. | Population pharmacokinetics tools and uses thereof |
| US9667321B2 (en) * | 2014-10-31 | 2017-05-30 | Pearson Education, Inc. | Predictive recommendation engine |
| EP3213232A1 (en) | 2014-10-30 | 2017-09-06 | Pearson Education, Inc. | Content database generation |
| ITMI20142149A1 (it) * | 2014-12-16 | 2016-06-16 | L I A Di Giuseppe Capasso | Apparato di diagnosi differenziale in medicina adattato per determinare la sequenza di test ottimale atta ad identificare una patologia secondo criteri di appropriatezza diagnostica |
| EP3271718A4 (en) * | 2015-03-18 | 2018-11-14 | The Regents of the University of California | Phenotypic personalized medicine: adaptive optimization of patient-specific combination therapy |
| SG10202009369SA (en) * | 2015-04-09 | 2020-10-29 | Diane Mould | Systems and methods for patient-specific dosing |
| WO2017146067A1 (ja) * | 2016-02-26 | 2017-08-31 | 株式会社豊崎会計事務所 | 情報処理装置 |
| SG11201808475XA (en) * | 2016-04-15 | 2018-10-30 | Baxalta Inc | Method and apparatus for providing a pharmacokinetic drug dosing regiment |
| US10896749B2 (en) | 2017-01-27 | 2021-01-19 | Shire Human Genetic Therapies, Inc. | Drug monitoring tool |
| GB201708624D0 (en) * | 2017-05-31 | 2017-07-12 | Sensidose Ab | System for evaluating dosage parameters |
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| WO2019195733A1 (en) * | 2018-04-05 | 2019-10-10 | University Of Maryland, Baltimore | Method and apparatus for individualized administration of medicaments for delivery within a therapeutic range |
| WO2019209845A1 (en) * | 2018-04-23 | 2019-10-31 | Mould Diane R | Systems and methods for modifying adaptive dosing regimens |
| WO2019213619A1 (en) | 2018-05-04 | 2019-11-07 | Abbott Laboratories | Hbv diagnostic, prognostic, and therapeutic methods and products |
| EP3815107A1 (en) * | 2018-06-28 | 2021-05-05 | Koninklijke Philips N.V. | Method and system for personalized hypertension treatment |
| US10810293B2 (en) * | 2018-10-16 | 2020-10-20 | Motorola Solutions, Inc. | Method and apparatus for dynamically adjusting biometric user authentication for accessing a communication device |
| CN111104054B (zh) * | 2018-10-29 | 2023-10-27 | 伊姆西Ip控股有限责任公司 | 管理输入/输出操作的方法、装置和计算机程序产品 |
| BE1027052A1 (fr) * | 2019-02-14 | 2020-09-07 | Aardex Group | Procede d'assistance a la prise ou a l'acte d'un traitement therapeutique |
| CA3132823A1 (en) * | 2019-03-08 | 2020-09-17 | Diane R. Mould | Systems and methods for drug-agnostic patient-specific dosing regimens |
| KR102876164B1 (ko) * | 2019-03-31 | 2025-10-28 | 레즈메드 아이엔씨. | 사용자로부터의 1개 이상의 분석물을 분석하는 방법 및 장치 |
| KR102062157B1 (ko) * | 2019-04-29 | 2020-01-03 | 오케스트로 주식회사 | 가상 머신 배치 방법 및 이를 구현하는 가상 머신 배치 장치 |
| JP7342491B2 (ja) * | 2019-07-25 | 2023-09-12 | オムロン株式会社 | 推論装置、推論方法、及び推論プログラム |
| KR102527404B1 (ko) * | 2019-10-29 | 2023-05-02 | 고려대학교 산학협력단 | 인슐린 투여량 조절 방법 |
| US11823782B2 (en) | 2020-03-03 | 2023-11-21 | Optum, Inc. | Systems, methods, apparatuses, and computer program products for administering pain management solutions remotely |
| US11075010B1 (en) | 2020-03-19 | 2021-07-27 | Insight RX, Inc. | Pharmacology model optimization based on distributed data acquisition |
| US20210304846A1 (en) * | 2020-03-29 | 2021-09-30 | Stephen J. Brown | Personalized compounding of therapeutic components and tracking of their influence on a measured parameter using a complex interaction model |
| EP4143846A1 (en) * | 2020-04-29 | 2023-03-08 | Novartis AG | A computer-implemented system and method for assessing a level of activity of a disease or condition in a patient's eye |
| US20210375455A1 (en) * | 2020-05-27 | 2021-12-02 | MediSync, Inc. | Artificial intelligence systems that incorporate expert knowledge related to heart failure |
| US12205705B2 (en) * | 2020-07-22 | 2025-01-21 | Optimdosing Llc | Smart nutrition dosing |
| KR102559883B1 (ko) * | 2020-09-03 | 2023-07-25 | 한양대학교 산학협력단 | 마르코프 의사결정 과정을 이용하는 투약 전략 생성 방법 |
| AU2022286921A1 (en) | 2021-05-29 | 2024-01-18 | Steven Molnar | Systems and methods for monoclonal antibody nomograms |
| KR20230036545A (ko) | 2021-09-07 | 2023-03-14 | 서울대학교산학협력단 | 적응적 설계 최적화 기반으로 하는 실험 최적화 시스템 및 그 방법 |
| US12046341B2 (en) * | 2021-10-05 | 2024-07-23 | Bradford Rabin | Methods and systems for electronically adjusting a dosing pattern of a patient undergoing a medical regimen |
| KR102815903B1 (ko) * | 2021-12-21 | 2025-05-30 | 충남대학교산학협력단 | 감염 환자에서 반코마이신 최적 용량을 결정하는 방법 |
| KR102821516B1 (ko) * | 2022-02-28 | 2025-06-17 | 한국전자기술연구원 | 목표 농도 조절 주입을 지원하는 약물 투여 장치 및 방법 |
| US20250312243A1 (en) * | 2022-04-28 | 2025-10-09 | Regents Of The University Of Michigan | Closed-loop architecture for distributing and administering medicines to patients |
| KR102447046B1 (ko) * | 2022-06-03 | 2022-09-26 | 주식회사 인투인월드 | 인공지능 기반 임상시험 프로토콜 설계 방법, 장치 및 시스템 |
| US12073931B2 (en) * | 2022-06-15 | 2024-08-27 | Express Scripts Strategic Development, Inc. | Alternate dose regimen identification system |
| WO2024059692A1 (en) | 2022-09-15 | 2024-03-21 | Abbott Laboratories | Hbv diagnostic, prognostic, and therapeutic methods and products |
| KR102873330B1 (ko) * | 2022-09-23 | 2025-10-21 | 재단법인 아산사회복지재단 | 머신러닝 기술을 활용한 항응고제 초기 적정 용량 예측 방법 및 장치 |
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| SG10202009369SA (en) | 2015-04-09 | 2020-10-29 | Diane Mould | Systems and methods for patient-specific dosing |
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2013
- 2013-10-07 EP EP13843939.3A patent/EP2904388B1/en active Active
- 2013-10-07 KR KR1020217005789A patent/KR102370479B1/ko active Active
- 2013-10-07 KR KR1020227006798A patent/KR102450486B1/ko active Active
- 2013-10-07 KR KR1020157011564A patent/KR102223018B1/ko active Active
- 2013-10-07 US US14/047,545 patent/US10083400B2/en active Active
- 2013-10-07 JP JP2015535867A patent/JP6412499B2/ja active Active
- 2013-10-07 SG SG10201907682R patent/SG10201907682RA/en unknown
- 2013-10-07 WO PCT/US2013/063691 patent/WO2014055978A1/en not_active Ceased
- 2013-10-07 SG SG11201502616WA patent/SG11201502616WA/en unknown
- 2013-10-07 AU AU2013326801A patent/AU2013326801A1/en not_active Abandoned
- 2013-10-07 EP EP23173217.3A patent/EP4224482A1/en active Pending
- 2013-10-07 CA CA2887072A patent/CA2887072C/en active Active
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2014
- 2014-08-12 US US14/457,601 patent/US10706364B2/en active Active
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2015
- 2015-04-02 IL IL238115A patent/IL238115B/en active IP Right Grant
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2017
- 2017-10-11 US US15/730,112 patent/US10268966B2/en active Active
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2018
- 2018-09-28 JP JP2018183803A patent/JP6653365B2/ja active Active
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2019
- 2019-01-07 IL IL264125A patent/IL264125B/en active IP Right Grant
- 2019-02-08 US US16/271,528 patent/US10740687B2/en active Active
- 2019-09-19 AU AU2019232874A patent/AU2019232874A1/en not_active Abandoned
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2020
- 2020-01-27 JP JP2020010887A patent/JP2020080161A/ja not_active Withdrawn
- 2020-02-19 IL IL272760A patent/IL272760B/en unknown
- 2020-07-02 US US16/919,247 patent/US20200334561A1/en not_active Abandoned
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2021
- 2021-10-06 AU AU2021245151A patent/AU2021245151A1/en not_active Abandoned
- 2021-10-14 US US17/501,851 patent/US11373743B2/en active Active
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2022
- 2022-06-10 JP JP2022094292A patent/JP7632886B2/ja active Active
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2023
- 2023-12-06 AU AU2023278028A patent/AU2023278028A1/en active Pending
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2024
- 2024-10-11 JP JP2024178764A patent/JP2024180539A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20181009 |
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| EEER | Examination request |
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| EEER | Examination request |
Effective date: 20181009 |
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| EEER | Examination request |
Effective date: 20181009 |
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| EEER | Examination request |
Effective date: 20181009 |
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| EEER | Examination request |
Effective date: 20181009 |
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| EEER | Examination request |
Effective date: 20181009 |
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| EEER | Examination request |
Effective date: 20181009 |
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| EEER | Examination request |
Effective date: 20181009 |