CA2882019C - Prostate specific antigen agents and methods of using same for prostate cancer imaging - Google Patents

Prostate specific antigen agents and methods of using same for prostate cancer imaging Download PDF

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Publication number
CA2882019C
CA2882019C CA2882019A CA2882019A CA2882019C CA 2882019 C CA2882019 C CA 2882019C CA 2882019 A CA2882019 A CA 2882019A CA 2882019 A CA2882019 A CA 2882019A CA 2882019 C CA2882019 C CA 2882019C
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CA
Canada
Prior art keywords
agent
ser
specific antigen
prostate specific
imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2882019A
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English (en)
French (fr)
Other versions
CA2882019A1 (en
Inventor
Guojie Ho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Visen Medical Inc
Original Assignee
Visen Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visen Medical Inc filed Critical Visen Medical Inc
Publication of CA2882019A1 publication Critical patent/CA2882019A1/en
Application granted granted Critical
Publication of CA2882019C publication Critical patent/CA2882019C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2882019A 2012-08-15 2013-03-15 Prostate specific antigen agents and methods of using same for prostate cancer imaging Active CA2882019C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261683305P 2012-08-15 2012-08-15
US61/683,305 2012-08-15
PCT/US2013/032200 WO2014028057A1 (en) 2012-08-15 2013-03-15 Prostate specific antigen agents and methods of using same for prostate cancer imaging

Publications (2)

Publication Number Publication Date
CA2882019A1 CA2882019A1 (en) 2014-02-20
CA2882019C true CA2882019C (en) 2021-02-09

Family

ID=48170795

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2882019A Active CA2882019C (en) 2012-08-15 2013-03-15 Prostate specific antigen agents and methods of using same for prostate cancer imaging

Country Status (7)

Country Link
US (1) US9371362B2 (https=)
EP (1) EP2885006B1 (https=)
JP (1) JP6370785B2 (https=)
CN (1) CN104955484B (https=)
AU (1) AU2013303233C1 (https=)
CA (1) CA2882019C (https=)
WO (1) WO2014028057A1 (https=)

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US9375493B2 (en) 2012-03-30 2016-06-28 Visen Medical, Inc. Bacterial imaging agents and methods of using same
CN104955484B (zh) 2012-08-15 2019-01-15 文森医学公司 用于前列腺癌成像的前列腺特异性抗原药剂及其使用方法
WO2014144702A2 (en) 2013-03-15 2014-09-18 Visen Medical, Inc. 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof
CA2901379C (en) 2013-03-15 2023-05-16 Visen Medical, Inc. Substituted silaxanthenium red to near-infrared fluorochromes for in vitro and in vivo imaging and detection
US9713649B2 (en) 2014-01-24 2017-07-25 The Cleveland Clinic Foundation PSMA-targeting imaging agents
ES2889904T3 (es) 2015-08-18 2022-01-14 Rakuten Medical Inc Conjugados de colorante de ftalocianina y su almacenamiento
US11154620B2 (en) 2015-08-18 2021-10-26 Rakuten Medical, Inc. Compositions, combinations and related methods for photoimmunotherapy
EA202090776A1 (ru) * 2017-10-23 2020-07-27 Дзе Джонс Хопкинс Юниверсити Визуализирующие и радиотерапевтические агенты, нацеленные на фибробласт-активирующий белок-альфа (fapalpha)
WO2024181456A1 (ja) * 2023-02-27 2024-09-06 富士フイルム株式会社 化合物及びこれを用いた標識生体物質
CN120752249A (zh) * 2023-02-27 2025-10-03 富士胶片株式会社 化合物及使用了该化合物的标记生物物质
WO2024181454A1 (ja) * 2023-02-27 2024-09-06 富士フイルム株式会社 化合物及びこれを用いた標識生体物質

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Also Published As

Publication number Publication date
US20140050662A1 (en) 2014-02-20
AU2013303233C1 (en) 2018-08-23
CN104955484B (zh) 2019-01-15
AU2013303233A1 (en) 2015-03-05
EP2885006B1 (en) 2018-08-08
CN104955484A (zh) 2015-09-30
US9371362B2 (en) 2016-06-21
JP6370785B2 (ja) 2018-08-08
JP2015532641A (ja) 2015-11-12
CA2882019A1 (en) 2014-02-20
AU2013303233B2 (en) 2018-05-17
WO2014028057A1 (en) 2014-02-20
EP2885006A1 (en) 2015-06-24

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