CA2881614A1 - Dual panel photodynamic therapy lamp - Google Patents
Dual panel photodynamic therapy lamp Download PDFInfo
- Publication number
- CA2881614A1 CA2881614A1 CA2881614A CA2881614A CA2881614A1 CA 2881614 A1 CA2881614 A1 CA 2881614A1 CA 2881614 A CA2881614 A CA 2881614A CA 2881614 A CA2881614 A CA 2881614A CA 2881614 A1 CA2881614 A1 CA 2881614A1
- Authority
- CA
- Canada
- Prior art keywords
- lamp
- leds
- treatment
- degrees
- modules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000002428 photodynamic therapy Methods 0.000 title claims abstract description 147
- 230000009977 dual effect Effects 0.000 title description 5
- 238000011282 treatment Methods 0.000 claims description 193
- 238000005286 illumination Methods 0.000 claims description 67
- 238000001816 cooling Methods 0.000 claims description 42
- 230000003287 optical effect Effects 0.000 claims description 10
- 239000000758 substrate Substances 0.000 claims description 6
- 239000003504 photosensitizing agent Substances 0.000 description 89
- 238000000034 method Methods 0.000 description 78
- 239000002243 precursor Substances 0.000 description 55
- 206010000496 acne Diseases 0.000 description 46
- 229960002749 aminolevulinic acid Drugs 0.000 description 45
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical class NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 description 43
- 208000002874 Acne Vulgaris Diseases 0.000 description 43
- 150000003839 salts Chemical class 0.000 description 40
- 210000003128 head Anatomy 0.000 description 33
- 210000003491 skin Anatomy 0.000 description 33
- -1 for example Chemical class 0.000 description 26
- 239000000203 mixture Substances 0.000 description 26
- 230000003902 lesion Effects 0.000 description 22
- 208000009621 actinic keratosis Diseases 0.000 description 13
- 210000004027 cell Anatomy 0.000 description 13
- 239000002537 cosmetic Substances 0.000 description 13
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 13
- 239000006071 cream Substances 0.000 description 12
- 230000002757 inflammatory effect Effects 0.000 description 12
- 201000010099 disease Diseases 0.000 description 10
- 238000011200 topical administration Methods 0.000 description 10
- 238000011534 incubation Methods 0.000 description 9
- 230000001681 protective effect Effects 0.000 description 9
- 208000002193 Pain Diseases 0.000 description 7
- 239000007787 solid Substances 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 description 6
- 239000003570 air Substances 0.000 description 6
- 230000001419 dependent effect Effects 0.000 description 6
- 210000001061 forehead Anatomy 0.000 description 6
- 239000000902 placebo Substances 0.000 description 6
- 229940068196 placebo Drugs 0.000 description 6
- 230000002829 reductive effect Effects 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 6
- 230000000007 visual effect Effects 0.000 description 6
- 206010015150 Erythema Diseases 0.000 description 5
- 230000001815 facial effect Effects 0.000 description 5
- 230000009467 reduction Effects 0.000 description 5
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical group O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 238000003491 array Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000001126 phototherapy Methods 0.000 description 4
- 238000002203 pretreatment Methods 0.000 description 4
- 206010051246 Photodermatosis Diseases 0.000 description 3
- 206010039509 Scab Diseases 0.000 description 3
- 208000000453 Skin Neoplasms Diseases 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 208000035475 disorder Diseases 0.000 description 3
- 230000002500 effect on skin Effects 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 231100000321 erythema Toxicity 0.000 description 3
- 210000000887 face Anatomy 0.000 description 3
- 239000006260 foam Substances 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 238000013178 mathematical model Methods 0.000 description 3
- 150000004702 methyl esters Chemical class 0.000 description 3
- 239000002674 ointment Substances 0.000 description 3
- 230000000699 topical effect Effects 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 206010033733 Papule Diseases 0.000 description 2
- 208000006994 Precancerous Conditions Diseases 0.000 description 2
- 201000004681 Psoriasis Diseases 0.000 description 2
- 238000000862 absorption spectrum Methods 0.000 description 2
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 2
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 2
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000013626 chemical specie Substances 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 210000005069 ears Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 230000004886 head movement Effects 0.000 description 2
- BTXNYTINYBABQR-UHFFFAOYSA-N hypericin Chemical compound C12=C(O)C=C(O)C(C(C=3C(O)=CC(C)=C4C=33)=O)=C2C3=C2C3=C4C(C)=CC(O)=C3C(=O)C3=C(O)C=C(O)C1=C32 BTXNYTINYBABQR-UHFFFAOYSA-N 0.000 description 2
- 229940005608 hypericin Drugs 0.000 description 2
- PHOKTTKFQUYZPI-UHFFFAOYSA-N hypericin Natural products Cc1cc(O)c2c3C(=O)C(=Cc4c(O)c5c(O)cc(O)c6c7C(=O)C(=Cc8c(C)c1c2c(c78)c(c34)c56)O)O PHOKTTKFQUYZPI-UHFFFAOYSA-N 0.000 description 2
- 238000011221 initial treatment Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000011369 optimal treatment Methods 0.000 description 2
- 239000006072 paste Substances 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 230000008845 photoaging Effects 0.000 description 2
- 150000004032 porphyrins Chemical class 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- SSKVDVBQSWQEGJ-UHFFFAOYSA-N pseudohypericin Natural products C12=C(O)C=C(O)C(C(C=3C(O)=CC(O)=C4C=33)=O)=C2C3=C2C3=C4C(C)=CC(O)=C3C(=O)C3=C(O)C=C(O)C1=C32 SSKVDVBQSWQEGJ-UHFFFAOYSA-N 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 210000004761 scalp Anatomy 0.000 description 2
- 239000000344 soap Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- OYINILBBZAQBEV-UWJYYQICSA-N (17s,18s)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid Chemical compound N1C2=C(C)C(C=C)=C1C=C(N1)C(C)=C(CC)C1=CC(C(C)=C1C(O)=O)=NC1=C(CC(O)=O)C([C@@H](CCC(O)=O)[C@@H]1C)=NC1=C2 OYINILBBZAQBEV-UWJYYQICSA-N 0.000 description 1
- ILBBNQMSDGAAPF-UHFFFAOYSA-N 1-(6-hydroxy-6-methylcyclohexa-2,4-dien-1-yl)propan-1-one Chemical compound CCC(=O)C1C=CC=CC1(C)O ILBBNQMSDGAAPF-UHFFFAOYSA-N 0.000 description 1
- MHIITNFQDPFSES-UHFFFAOYSA-N 25,26,27,28-tetrazahexacyclo[16.6.1.13,6.18,11.113,16.019,24]octacosa-1(25),2,4,6,8(27),9,11,13,15,17,19,21,23-tridecaene Chemical class N1C(C=C2C3=CC=CC=C3C(C=C3NC(=C4)C=C3)=N2)=CC=C1C=C1C=CC4=N1 MHIITNFQDPFSES-UHFFFAOYSA-N 0.000 description 1
- KFKRXESVMDBTNQ-UHFFFAOYSA-N 3-[18-(2-carboxylatoethyl)-8,13-bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-21,24-diium-2-yl]propanoate Chemical class N1C2=C(C)C(C(C)O)=C1C=C(N1)C(C)=C(C(O)C)C1=CC(C(C)=C1CCC(O)=O)=NC1=CC(C(CCC(O)=O)=C1C)=NC1=C2 KFKRXESVMDBTNQ-UHFFFAOYSA-N 0.000 description 1
- 206010000501 Acne conglobata Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000013165 Bowen disease Diseases 0.000 description 1
- 208000019337 Bowen disease of the skin Diseases 0.000 description 1
- VSEIDZLLWQQJGK-CHOZPQDDSA-N CCC1=C(C)C2=N\C\1=C/C1=C(C)C(C(O)=O)=C(N1)\C(CC(=O)N[C@@H](CC(O)=O)C(O)=O)=C1/N=C(/C=C3\N/C(=C\2)C(C=C)=C3C)[C@@H](C)[C@@H]1CCC(O)=O Chemical compound CCC1=C(C)C2=N\C\1=C/C1=C(C)C(C(O)=O)=C(N1)\C(CC(=O)N[C@@H](CC(O)=O)C(O)=O)=C1/N=C(/C=C3\N/C(=C\2)C(C=C)=C3C)[C@@H](C)[C@@H]1CCC(O)=O VSEIDZLLWQQJGK-CHOZPQDDSA-N 0.000 description 1
- 241000186427 Cutibacterium acnes Species 0.000 description 1
- 241001464974 Cutibacterium avidum Species 0.000 description 1
- 241001464975 Cutibacterium granulosum Species 0.000 description 1
- 241001635598 Enicostema Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010027626 Milia Diseases 0.000 description 1
- LYPFDBRUNKHDGX-SOGSVHMOSA-N N1C2=CC=C1\C(=C1\C=CC(=N1)\C(=C1\C=C/C(/N1)=C(/C1=N/C(/CC1)=C2/C1=CC(O)=CC=C1)C1=CC(O)=CC=C1)\C1=CC(O)=CC=C1)C1=CC(O)=CC=C1 Chemical compound N1C2=CC=C1\C(=C1\C=CC(=N1)\C(=C1\C=C/C(/N1)=C(/C1=N/C(/CC1)=C2/C1=CC(O)=CC=C1)C1=CC(O)=CC=C1)\C1=CC(O)=CC=C1)C1=CC(O)=CC=C1 LYPFDBRUNKHDGX-SOGSVHMOSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 241001459566 Papulosa Species 0.000 description 1
- 208000012641 Pigmentation disease Diseases 0.000 description 1
- 241000186429 Propionibacterium Species 0.000 description 1
- 206010037888 Rash pustular Diseases 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- 206010043189 Telangiectasia Diseases 0.000 description 1
- 206010066901 Treatment failure Diseases 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- KMWBBMXGHHLDKL-UHFFFAOYSA-N [AlH3].[Si] Chemical compound [AlH3].[Si] KMWBBMXGHHLDKL-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 150000004036 bacteriochlorins Chemical class 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000004035 chlorins Chemical class 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229910001882 dioxygen Inorganic materials 0.000 description 1
- 208000037765 diseases and disorders Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000000295 emission spectrum Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 150000001261 hydroxy acids Chemical class 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 239000003410 keratolytic agent Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 231100001079 no serious adverse effect Toxicity 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
- 201000004700 rosacea Diseases 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
- 238000005201 scrubbing Methods 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 208000008742 seborrheic dermatitis Diseases 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036555 skin type Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 206010041823 squamous cell carcinoma Diseases 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 229950010924 talaporfin Drugs 0.000 description 1
- 208000009056 telangiectasis Diseases 0.000 description 1
- 229960002197 temoporfin Drugs 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- ZQFGRJWRSLZCSQ-ZSFNYQMMSA-N verteporfin Chemical compound C=1C([C@@]2([C@H](C(=O)OC)C(=CC=C22)C(=O)OC)C)=NC2=CC(C(=C2C=C)C)=NC2=CC(C(=C2CCC(O)=O)C)=NC2=CC2=NC=1C(C)=C2CCC(=O)OC ZQFGRJWRSLZCSQ-ZSFNYQMMSA-N 0.000 description 1
- 229960003895 verteporfin Drugs 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 210000000216 zygoma Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0616—Skin treatment other than tanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N2005/002—Cooling systems
- A61N2005/007—Cooling systems for cooling the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0632—Constructional aspects of the apparatus
- A61N2005/0633—Arrangements for lifting or hinging the frame which supports the light sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0642—Irradiating part of the body at a certain distance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0652—Arrays of diodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
- A61N2005/0663—Coloured light
Landscapes
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiation-Therapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12182486 | 2012-08-30 | ||
| EP12182486.6 | 2012-08-30 | ||
| PCT/EP2013/067982 WO2014033254A1 (en) | 2012-08-30 | 2013-08-30 | Dual panel photodynamic therapy lamp |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2881614A1 true CA2881614A1 (en) | 2014-03-06 |
Family
ID=46888911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2881614A Abandoned CA2881614A1 (en) | 2012-08-30 | 2013-08-30 | Dual panel photodynamic therapy lamp |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20140067024A1 (https=) |
| EP (1) | EP2890458B1 (https=) |
| JP (1) | JP2015528338A (https=) |
| BR (1) | BR112015004114A2 (https=) |
| CA (1) | CA2881614A1 (https=) |
| EA (1) | EA201590362A1 (https=) |
| ES (1) | ES2685326T3 (https=) |
| WO (1) | WO2014033254A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110393862A (zh) * | 2019-08-28 | 2019-11-01 | 武汉优瑞科技有限公司 | 一种用于耳朵治疗的光子治疗仪 |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014026077A1 (en) * | 2012-08-10 | 2014-02-13 | Dusa Pharmaceuticals, Inc. | Method for the treatment of acne |
| EP3065823B1 (en) * | 2013-11-06 | 2020-09-09 | Terry Ward | Cellulite and fat reducing device and method utilizing optical emitters |
| JP6595484B2 (ja) | 2013-12-20 | 2019-10-23 | ガルデルマ・リサーチ・アンド・デヴェロップメント | 光損傷皮膚のパルス光力学的処置 |
| PL410162A1 (pl) | 2014-11-17 | 2016-05-23 | Wojskowa Akademia Techniczna | Oświetlacz LED z wyjściem światłowodowym |
| JP6516219B2 (ja) * | 2015-06-24 | 2019-05-22 | 公立大学法人名古屋市立大学 | 光線力学的治療用光照射装置 |
| US12109429B2 (en) | 2015-07-28 | 2024-10-08 | Know Bio, Llc | Phototherapeutic light for treatment of pathogens |
| CN111701144B (zh) | 2015-07-28 | 2023-03-21 | 诺欧生物有限责任公司 | 用于对一氧化氮的光疗调节的系统和方法 |
| EP3362145B1 (en) | 2015-10-15 | 2021-01-06 | DUSA Pharmaceuticals, Inc. | Adjustable illuminator for photodynamic therapy and diagnosis |
| US10603508B2 (en) * | 2015-10-15 | 2020-03-31 | Dusa Pharmaceuticals, Inc. | Adjustable illuminators and methods for photodynamic therapy and diagnosis |
| FI20155784A7 (fi) * | 2015-11-02 | 2017-05-03 | Cryotech Nordic Oue | Automatisoitu järjestelmä laser-avusteiseen dermatologiseen hoitoon ja ohjausmenetelmä |
| GB201522398D0 (en) * | 2015-12-18 | 2016-02-03 | Photocure As | Device for photodynamic therapy |
| CN106237534B (zh) * | 2016-08-29 | 2018-06-29 | 武汉亚格光电技术股份有限公司 | 智能型鲜红斑痣光动力治疗仪系统 |
| WO2018117787A1 (es) * | 2016-12-19 | 2018-06-28 | Castro Baldenebro Brayan Gamaniel | Sistema de aplicación de luz focalizada para tratamiento de afecciones de la piel causada por acné |
| CA3057840A1 (en) * | 2017-04-14 | 2018-10-18 | Dusa Pharmaceuticals, Inc. | Adjustable illuminators and methods for photodynamic therapy and diagnosis |
| US12233279B2 (en) | 2017-05-30 | 2025-02-25 | Icahn School Of Medicine At Mount Sinai | Device for photo-therapy and use thereof |
| US11273320B2 (en) | 2017-05-30 | 2022-03-15 | Tcellerate Llc | Device for photo-therapy of Grover's disease and use thereof |
| US10155122B1 (en) * | 2017-05-30 | 2018-12-18 | William Woodburn | Device for photo-therapy of grover's disease and use thereof |
| US20200261580A1 (en) * | 2017-07-17 | 2020-08-20 | Andrea Willey | Photodynamic Therapy Method for Skin Disorders |
| CN108310674B (zh) * | 2017-12-21 | 2019-08-13 | 宁波大学 | 一种用于光动力治疗的光源 |
| US10357567B1 (en) | 2018-01-12 | 2019-07-23 | Dusa Pharmaceuticals, Inc. | Methods for photodynamic therapy |
| CN108543226B (zh) * | 2018-04-27 | 2020-01-07 | 王淑娟 | 一种可多角度实施治疗的骨伤恢复烤灯 |
| JP7336756B2 (ja) * | 2018-09-28 | 2023-09-01 | 公立大学法人名古屋市立大学 | 光線治療装置および光線治療装置の光出射方法 |
| US10478635B1 (en) | 2018-10-22 | 2019-11-19 | Joovv, Inc. | Photobiomodulation therapy systems and methods |
| US11458328B2 (en) | 2018-10-22 | 2022-10-04 | Joovv, Inc. | Photobiomodulation therapy device accessories |
| KR102100567B1 (ko) * | 2018-11-14 | 2020-04-13 | 최순철 | 피부관리기 |
| AU2020303417B2 (en) * | 2019-06-25 | 2025-08-28 | Sun Pharmaceutical Industries, Inc. | Methods for reducing pain during photodynamic therapy of actinic keratosis |
| US12011611B2 (en) | 2020-03-19 | 2024-06-18 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11986666B2 (en) | 2020-03-19 | 2024-05-21 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US12447354B2 (en) | 2020-03-19 | 2025-10-21 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11147984B2 (en) | 2020-03-19 | 2021-10-19 | Know Bio, Llc | Illumination devices for inducing biological effects |
| WO2021256369A1 (ja) * | 2020-06-19 | 2021-12-23 | パナソニックＩｐマネジメント株式会社 | 光照射型美容装置及び電子機器 |
| US11235169B1 (en) * | 2020-10-15 | 2022-02-01 | Biofrontera Pharma Gmbh | Illumination device for photodynamic therapy, method for treating a skin disease and method for operating an illumination device |
| US12347337B2 (en) | 2020-12-10 | 2025-07-01 | Know Bio, Llc | Enhanced testing and characterization techniques for phototherapeutic light treatments |
| CN112972904B (zh) * | 2021-02-22 | 2022-06-07 | 四川大学华西医院 | 一种模块化的led灯光动力治疗仪 |
| US11654294B2 (en) | 2021-03-15 | 2023-05-23 | Know Bio, Llc | Intranasal illumination devices |
| US12115384B2 (en) | 2021-03-15 | 2024-10-15 | Know Bio, Llc | Devices and methods for illuminating tissue to induce biological effects |
| ES2928172B2 (es) * | 2021-05-14 | 2023-04-26 | Univ Alcala Henares | Dispositivo luminoso con diodos led orientados |
| US20230043049A1 (en) * | 2021-08-09 | 2023-02-09 | Photonic Healing, LLC DBA Visum Light | Mobile configurable light therapy device |
| USD1073965S1 (en) * | 2021-08-10 | 2025-05-06 | Medmix Co., Ltd. | Medical LED skin enhancement apparatus |
| US20230181923A1 (en) * | 2021-12-09 | 2023-06-15 | Zerigo Health, Inc. | Apparatus and method for treating skin lesions |
| USD1010838S1 (en) * | 2022-01-26 | 2024-01-09 | Kernel Medical Equipment Co., Ltd | Photodynamic therapy device |
| JP2023109524A (ja) * | 2022-01-27 | 2023-08-08 | キヤノンメディカルシステムズ株式会社 | 光照射計画装置、光照射支援装置、医用情報処理システム及び医用情報処理方法 |
| USD1060697S1 (en) * | 2022-08-19 | 2025-02-04 | HOT Brands, LLC | Stand-up red light therapy device |
| KR102511380B1 (ko) | 2022-10-07 | 2023-03-17 | 주식회사 다람 | 남성 생식기 웨어러블 장치 |
| USD1052103S1 (en) * | 2022-10-18 | 2024-11-19 | Biofrontera Pharma Gmbh | Photodynamic therapy lamp head |
| USD1067446S1 (en) * | 2022-10-18 | 2025-03-18 | Biofrontera Pharma Gmbh | Photodynamic therapy lamp |
| EP4605072A1 (en) * | 2022-10-20 | 2025-08-27 | Biofrontera Pharma GmbH | Illumination device for photodynamic therapy, method for treating a skin disease and method for operating an illumination device |
| USD1114317S1 (en) * | 2023-05-26 | 2026-02-17 | Kavo Dental Gmbh | Medical light |
| WO2025160272A1 (en) * | 2024-01-24 | 2025-07-31 | Biofrontera Inc. | Illumination device |
| USD1077259S1 (en) * | 2024-09-02 | 2025-05-27 | Chen Guo | Red light therapy device |
| USD1073918S1 (en) | 2024-12-03 | 2025-05-06 | Erchonia Corporation, Llc | Floor stand for phototherapy device |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4740707A (en) * | 1986-10-27 | 1988-04-26 | Allan Thaw | Portable tanning unit |
| US5420768A (en) | 1993-09-13 | 1995-05-30 | Kennedy; John | Portable led photocuring device |
| ATE202076T1 (de) | 1995-03-10 | 2001-06-15 | Photocure Asa | Ester der 5-aminolevulinsäure als mittel zur photosensibilisierung in der chemotherapie |
| US6712481B2 (en) | 1995-06-27 | 2004-03-30 | Solid State Opto Limited | Light emitting panel assemblies |
| NO972244L (no) | 1997-05-15 | 1998-11-16 | Photocure | Innretning for belysning av et avgrenset omrÕde |
| FR2777782B1 (fr) | 1998-04-22 | 2001-05-18 | Alexandre Marti | Solution pour la preparation d'une substance pharmaceutique pour le diagnostic et/ou le traitement de lesions tissulaires |
| US6663659B2 (en) | 2000-01-13 | 2003-12-16 | Mcdaniel David H. | Method and apparatus for the photomodulation of living cells |
| US6936044B2 (en) | 1998-11-30 | 2005-08-30 | Light Bioscience, Llc | Method and apparatus for the stimulation of hair growth |
| US20060212025A1 (en) | 1998-11-30 | 2006-09-21 | Light Bioscience, Llc | Method and apparatus for acne treatment |
| US6887260B1 (en) | 1998-11-30 | 2005-05-03 | Light Bioscience, Llc | Method and apparatus for acne treatment |
| US20030216795A1 (en) | 1999-07-07 | 2003-11-20 | Yoram Harth | Apparatus and method for high energy photodynamic therapy of acne vulgaris, seborrhea and other skin disorders |
| US20020128695A1 (en) * | 1999-07-07 | 2002-09-12 | Yoram Harth | Apparatus and method for high energy photodynamic therapy of acne vulgaris and seborrhea |
| US20040122492A1 (en) | 1999-07-07 | 2004-06-24 | Yoram Harth | Phototherapeutic treatment of skin conditions |
| GB2370992B (en) * | 2000-03-23 | 2002-11-20 | Photo Therapeutics Ltd | Therapeutic light source and method |
| US7311722B2 (en) | 2001-01-22 | 2007-12-25 | Eric Larsen | Photodynamic stimulation device and methods |
| GB0113899D0 (en) * | 2001-06-07 | 2001-08-01 | Photocure Asa | Photodynamic therapy lamp |
| EP1312353A1 (en) | 2001-11-16 | 2003-05-21 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for hair removal |
| US20060293727A1 (en) | 2002-05-09 | 2006-12-28 | Greg Spooner | System and method for treating exposed tissue with light emitting diodes |
| US20080091250A1 (en) | 2002-09-26 | 2008-04-17 | Lumiport, Llc | Light therapy desk lamp |
| US6872220B2 (en) | 2003-01-16 | 2005-03-29 | Lumitex, Inc. | Infant phototherapy positioning system |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
| US7207694B1 (en) | 2004-08-20 | 2007-04-24 | Boyd Industries, Inc. | Light emitting diode operating and examination light system |
| GB0424833D0 (en) | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
| WO2006060905A1 (en) * | 2004-12-07 | 2006-06-15 | Elumen Lighting Networks Inc. | Assembly of light emitting diodes for lighting applications |
| US20060229689A1 (en) * | 2005-04-08 | 2006-10-12 | Led Technologies, Llc | LED therapy device |
| CA2642741A1 (en) | 2006-01-24 | 2007-08-02 | Nomir Medical Technologies, Inc. | Optical method and device for modulation of biochemical processes in adipose tissue |
| US7517101B2 (en) * | 2006-03-28 | 2009-04-14 | Tobin Stephen M | Convertible lamp array |
| GB0700580D0 (en) | 2007-01-11 | 2007-02-21 | Photocure Asa | Use |
| JP3133297U (ja) * | 2007-04-25 | 2007-07-05 | 聰章 張 | 方向自在光線療法用具 |
| GB0724279D0 (en) | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
| AU2008337067A1 (en) | 2007-12-14 | 2009-06-25 | Photoderma Sa | Novel compounds useful in therapeutic and cosmetic methods |
| RU2010139765A (ru) | 2008-02-28 | 2012-04-10 | Конинклейке Филипс Электроникс, Н.В. (Nl) | Устройство для распределения света от множества источников для устранения видимых границ между ними, устройства для световой терапии, включающие такое устройство и способы |
| GB0807850D0 (en) * | 2008-04-30 | 2008-06-04 | Photopharmica Ltd | Treatment device |
| US20100106228A1 (en) | 2008-10-27 | 2010-04-29 | Steven Gardner | Device and method of phototherapy for jaundiced infants |
| GB0823472D0 (en) | 2008-12-23 | 2009-01-28 | Photocure Asa | Product |
| GB0900461D0 (en) * | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
| US8734163B1 (en) * | 2009-04-28 | 2014-05-27 | Musco Corporation | Apparatus, method, and system for on-site evaluation of illumination scheme using a mobile lighting evaluation system |
| DE102010023258A1 (de) | 2009-06-09 | 2011-04-07 | Helbo Photodynamic Systems Gmbh & Co. Kg | Vorrichtung und Verfahren für die photodynamische Therapie |
| RU2526803C2 (ru) | 2009-06-11 | 2014-08-27 | ФотоКьюэр АСА | Полутвердые композиции и фармацевтические продукты |
| JP2012529451A (ja) | 2009-06-11 | 2012-11-22 | フォトキュア エイエスエイ | ５−アミノレブリン酸を含む固体組成物 |
| CA2790827A1 (en) | 2010-03-01 | 2011-09-09 | Photocure Asa | Cosmetic compositions |
| EP2585111A1 (en) | 2010-06-23 | 2013-05-01 | Photocure ASA | Hyperosmotic preparations comprising 5 -amino levulinic acid or derivative as photosensitizing agent |
| JP5991970B2 (ja) | 2010-07-09 | 2016-09-14 | フォトキュア エイエスエイ | 光力学的治療または光力学的診断で使用する乾燥組成物および当該乾燥組成物を含む装置 |
-
2012
- 2012-10-05 US US13/646,274 patent/US20140067024A1/en not_active Abandoned
-
2013
- 2013-08-30 EP EP13756136.1A patent/EP2890458B1/en not_active Not-in-force
- 2013-08-30 WO PCT/EP2013/067982 patent/WO2014033254A1/en not_active Ceased
- 2013-08-30 ES ES13756136.1T patent/ES2685326T3/es active Active
- 2013-08-30 JP JP2015529032A patent/JP2015528338A/ja active Pending
- 2013-08-30 BR BR112015004114A patent/BR112015004114A2/pt not_active IP Right Cessation
- 2013-08-30 CA CA2881614A patent/CA2881614A1/en not_active Abandoned
- 2013-08-30 EA EA201590362A patent/EA201590362A1/ru unknown
-
2015
- 2015-09-24 US US14/863,987 patent/US9399146B2/en not_active Expired - Fee Related
-
2016
- 2016-09-01 US US15/254,850 patent/US20160367832A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110393862A (zh) * | 2019-08-28 | 2019-11-01 | 武汉优瑞科技有限公司 | 一种用于耳朵治疗的光子治疗仪 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014033254A1 (en) | 2014-03-06 |
| BR112015004114A2 (pt) | 2017-07-04 |
| EP2890458B1 (en) | 2018-05-30 |
| JP2015528338A (ja) | 2015-09-28 |
| US20160008623A1 (en) | 2016-01-14 |
| US20160367832A1 (en) | 2016-12-22 |
| US20140067024A1 (en) | 2014-03-06 |
| US9399146B2 (en) | 2016-07-26 |
| EP2890458A1 (en) | 2015-07-08 |
| EA201590362A1 (ru) | 2015-11-30 |
| ES2685326T3 (es) | 2018-10-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9399146B2 (en) | Methods of treating acne using dual panel photodynamic therapy lamp | |
| US20250235715A1 (en) | Adjustable illuminator for photodynamic therapy and diagnosis | |
| US20230321243A1 (en) | Methods for photodynamic therapy | |
| Sorbellini et al. | Photodynamic and photobiological effects of light-emitting diode (LED) therapy in dermatological disease: an update | |
| Sakamoto et al. | Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice: part II. Understanding parameters for acne treatment with photodynamic therapy | |
| Keyal et al. | Photodynamic therapy for the treatment of different severity of acne: A systematic review | |
| Moseley et al. | Ambulatory photodynamic therapy: a new concept in delivering photodynamic therapy | |
| Garcia-Zuazaga et al. | Photodynamic therapy in dermatology: current concepts in the treatment of skin cancer | |
| Nguyen et al. | An update on topical photodynamic therapy for clinical dermatologists | |
| US20110224598A1 (en) | Radiant near infrared light emitting diode exposure as skin preparation | |
| Tao et al. | Low-dose topical 5-aminolevulinic acid photodynamic therapy in the treatment of different severity of acne vulgaris | |
| JP2024543045A (ja) | 光力学的療法の照明器および方法 | |
| Falkenberg et al. | Pretreatment with ablative fractional carbon dioxide laser improves treatment efficacy in a synergistic PDT protocol for actinic keratoses on the head | |
| Ishii et al. | Light and laser-based therapy in treatment of acne vulgaris: A clinical review | |
| Torezan et al. | Photodynamic therapy in dermatology: basic principles | |
| Peterson et al. | Photodynamic therapy | |
| ES2778031T3 (es) | Método para el tratamiento del acné | |
| JP2024527985A (ja) | 設定可能な光線力学的療法システム及び方法 | |
| Kocki et al. | Nurses and pharmacists in interdisciplinary team of health care providers in photodynamic therapy | |
| Savas et al. | Photodynamic therapy | |
| Gu et al. | Light-emitting diodes for healthcare and well-being | |
| Andreev et al. | Photodynamic therapy as an up-to-date medical technology for the treatment of vulgar acne | |
| Golbari et al. | Daylight Photodynamic Therapy for Actinic Keratosis | |
| Petersona et al. | Photodynamic therapy in treating actinic keratosis and photorejuvenation | |
| Gold | Lasers and Light Sources for Medical Dermatologic Conditions |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |
Effective date: 20190830 |