CA2881321A1 - Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases - Google Patents

Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases Download PDF

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Publication number
CA2881321A1
CA2881321A1 CA2881321A CA2881321A CA2881321A1 CA 2881321 A1 CA2881321 A1 CA 2881321A1 CA 2881321 A CA2881321 A CA 2881321A CA 2881321 A CA2881321 A CA 2881321A CA 2881321 A1 CA2881321 A1 CA 2881321A1
Authority
CA
Canada
Prior art keywords
cndot
deficiency
mitochondria
mitochondrial
microglobulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2881321A
Other languages
English (en)
French (fr)
Inventor
Bo Akerstrom
Magnus Gram
Lena Rosenlof
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guard Therapeutics International AB
Original Assignee
A1M Pharma AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A1M Pharma AB filed Critical A1M Pharma AB
Publication of CA2881321A1 publication Critical patent/CA2881321A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1722Plasma globulins, lactoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2881321A 2012-09-05 2013-09-04 Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases Abandoned CA2881321A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201270538 2012-09-05
DKPA201270538 2012-09-05
DKPA201270557 2012-09-12
DKPA201270557 2012-09-12
PCT/EP2013/068270 WO2014037390A1 (en) 2012-09-05 2013-09-04 Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases

Publications (1)

Publication Number Publication Date
CA2881321A1 true CA2881321A1 (en) 2014-03-13

Family

ID=49162118

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2881321A Abandoned CA2881321A1 (en) 2012-09-05 2013-09-04 Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases

Country Status (21)

Country Link
US (1) US10226507B2 (en:Method)
EP (1) EP2900254B1 (en:Method)
JP (2) JP2015533790A (en:Method)
KR (1) KR20150047510A (en:Method)
CN (1) CN104661673A (en:Method)
AU (1) AU2013311714C1 (en:Method)
BR (1) BR112015003957A2 (en:Method)
CA (1) CA2881321A1 (en:Method)
DK (1) DK2900254T3 (en:Method)
EA (1) EA028963B1 (en:Method)
ES (1) ES2599034T3 (en:Method)
HR (1) HRP20161364T1 (en:Method)
HU (1) HUE030559T2 (en:Method)
IN (1) IN2015DN00515A (en:Method)
MX (1) MX357656B (en:Method)
NZ (1) NZ629621A (en:Method)
PL (1) PL2900254T3 (en:Method)
PT (1) PT2900254T (en:Method)
SG (1) SG11201500669SA (en:Method)
WO (1) WO2014037390A1 (en:Method)
ZA (1) ZA201500547B (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110452980A (zh) * 2019-09-23 2019-11-15 武汉儿童医院 一种线粒体脑肌病诊断试剂盒及应用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016204360A (ja) * 2015-02-25 2016-12-08 エー1エム ファーマ エービーA1M Pharma AB 放射性核種療法における腎臓の保護に用いるためのアルファ−1−ミクログロブリン
CA3014850A1 (en) * 2016-02-25 2017-08-31 A1M Pharma Ab Alpha-1-microglobulin for use in the protection of kidneys in connection with use of contrast media
EA039776B1 (ru) * 2016-03-18 2022-03-11 Гард Терапьютикс Интернэшнл Айби Новые белки, полученные из альфа-1-микроглобулина, и их применение
GB2566516A (en) 2017-09-15 2019-03-20 Univ Oxford Innovation Ltd Electrochemical recognition and quantification of cytochrome c oxidase expression in bacteria
CN109867717A (zh) * 2019-04-01 2019-06-11 山西瑞亚力生物技术有限公司 一种血浆中α1微球蛋白的提取方法
WO2021062007A1 (en) * 2019-09-25 2021-04-01 Cytegen Corp. Treatment of mitochondrial deficits and age-related diseases using blood products
CN115575646B (zh) * 2022-11-21 2023-04-28 四川大学华西医院 一种代谢标志物组在制备预测癫痫发作的试剂盒中的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004292775A1 (en) * 2003-11-26 2005-06-09 Sanofi-Aventis Deutschland Gmbh Tubular proteinuria as an indicator for elevated cardiovascular risk
PL2111555T3 (pl) * 2007-02-12 2013-10-31 A1M Pharma Ab Diagnostyka stanu przedrzucawkowego
PL2300614T3 (pl) * 2008-02-04 2016-04-29 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Sposoby i kompozycje do leczenia zaburzeń mitochondrialnych
WO2010006809A2 (en) 2008-07-18 2010-01-21 Akerstroem Bo Medical use of the radical scavenger and antioxidant alpha-1-microglobulin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110452980A (zh) * 2019-09-23 2019-11-15 武汉儿童医院 一种线粒体脑肌病诊断试剂盒及应用

Also Published As

Publication number Publication date
WO2014037390A1 (en) 2014-03-13
ZA201500547B (en) 2017-09-27
SG11201500669SA (en) 2015-02-27
JP2015533790A (ja) 2015-11-26
EP2900254B1 (en) 2016-08-03
IN2015DN00515A (en:Method) 2015-06-26
PL2900254T3 (pl) 2017-02-28
ES2599034T3 (es) 2017-01-31
BR112015003957A2 (pt) 2017-08-08
AU2013311714C1 (en) 2018-01-25
PT2900254T (pt) 2016-10-18
CN104661673A (zh) 2015-05-27
MX2015002604A (es) 2015-06-10
EA028963B1 (ru) 2018-01-31
HRP20161364T1 (hr) 2016-12-16
DK2900254T3 (en) 2016-08-29
NZ629621A (en) 2015-09-25
HK1210585A1 (en) 2016-04-29
EA201590503A1 (ru) 2015-06-30
KR20150047510A (ko) 2015-05-04
AU2013311714A1 (en) 2015-03-12
US20150258171A1 (en) 2015-09-17
EP2900254A1 (en) 2015-08-05
JP2018203756A (ja) 2018-12-27
HUE030559T2 (en) 2017-05-29
AU2013311714B2 (en) 2017-10-12
US10226507B2 (en) 2019-03-12
MX357656B (es) 2018-07-18

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Legal Events

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EEER Examination request

Effective date: 20180822

FZDE Discontinued

Effective date: 20220406

FZDE Discontinued

Effective date: 20220406