CA2877299C - Methods of treating or preventing periodontitis and diseases associated with periodontitis - Google Patents
Methods of treating or preventing periodontitis and diseases associated with periodontitis Download PDFInfo
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- CA2877299C CA2877299C CA2877299A CA2877299A CA2877299C CA 2877299 C CA2877299 C CA 2877299C CA 2877299 A CA2877299 A CA 2877299A CA 2877299 A CA2877299 A CA 2877299A CA 2877299 C CA2877299 C CA 2877299C
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- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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| US9579360B2 (en) * | 2012-06-20 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
| KR102383714B1 (ko) | 2014-02-25 | 2022-04-07 | 아칠리온 파르마세우티칼스 인코포레이티드 | 보체 매개 질환의 치료를 위한 아릴, 헤테로아릴 및 헤테로사이클릭 화합물 |
| SI3154561T1 (sl) | 2014-06-12 | 2019-11-29 | Ra Pharmaceuticals Inc | Modulacija aktivnosti komplementa |
| EP3988110A1 (en) | 2015-01-28 | 2022-04-27 | RA Pharmaceuticals, Inc. | Modulators of complement activity |
| WO2017035409A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders |
| WO2017035405A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of immune and inflammatory disorders |
| WO2017035401A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amide compounds for treatment of immune and inflammatory disorders |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| CA3007772A1 (en) | 2015-12-16 | 2017-06-22 | Ra Pharmaceuticals, Inc. | Modulators of complement activity |
| CA3045114A1 (en) | 2016-12-07 | 2018-06-14 | Ra Pharmaceuticals, Inc. | Modulators of complement activity |
| KR102632860B1 (ko) | 2017-03-01 | 2024-02-02 | 아칠리온 파르마세우티칼스 인코포레이티드 | 의학적 장애의 치료를 위한 아릴, 헤테로아릴, 및 헤테로사이클릭 약학적 화합물 |
| WO2018160891A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceutical, Inc. | Pharmaceutical compounds for treatment of medical disorders |
| EP3661493A4 (en) | 2017-08-02 | 2021-04-14 | Achillion Pharmaceuticals, Inc. | TREATMENT DIET FOR THE TREATMENT OF PAROXYSTIC NOCTURAL HEMOGLOBINURIA |
| US20210000927A1 (en) | 2017-12-04 | 2021-01-07 | Ra Pharmaceuticals, Inc. | Modulators of complement activity |
| US20200316163A1 (en) | 2017-12-15 | 2020-10-08 | Apellis Pharmaceuticals, Inc. | Dosing regimens and related compositions and methods |
| HUE057693T2 (hu) | 2018-04-06 | 2022-05-28 | Univ Pennsylvania | Fokozott oldhatóságú és javított farmakokinetikai tulajdonságú kompsztatin analógok |
| WO2020051538A1 (en) | 2018-09-06 | 2020-03-12 | Achillion Pharmaceuticals, Inc. | Morphic forms of complement factor d inhibitors |
| US11814391B2 (en) | 2018-09-06 | 2023-11-14 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
| AU2019346464A1 (en) | 2018-09-25 | 2021-04-08 | Achillion Pharmaceuticals, Inc. | Morphic forms of complement factor D inhibitors |
| US12239645B2 (en) | 2018-12-17 | 2025-03-04 | Achillion Pharmaceuticals, Inc. | Targeted dosing for the treatment of complement mediated disorders |
| CN113543796A (zh) | 2019-03-08 | 2021-10-22 | Ra制药公司 | 齐鲁考普作为深层组织穿透性c5抑制剂 |
| TW202102481A (zh) | 2019-03-29 | 2021-01-16 | 美商Ｒａ製藥公司 | 補體調節劑和相關方法 |
| BR112021017820A2 (pt) | 2019-04-24 | 2022-02-08 | Ra Pharmaceuticals Inc | Composições e métodos para modulação da atividade de complemento |
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| ES2600460T3 (es) * | 2005-05-10 | 2017-02-09 | Intermune, Inc. | Derivados de piridona-2-ona como moduladores del sistema de proteína cinasa activada por estrés |
| HUE026001T2 (en) * | 2007-02-05 | 2016-04-28 | Apellis Pharmaceuticals Inc | Compstatin analogues for use in the treatment of the inflammatory condition of the respiratory system |
| WO2010056399A1 (en) * | 2008-11-17 | 2010-05-20 | Incode Biopharmaceutics, Inc. | Method and composition for modulating the immune system and various inflammatory conditions comprising complement depletors |
| EP2424557B1 (en) * | 2009-05-01 | 2017-10-25 | The Trustees Of The University Of Pennsylvania | Modified compstatin with peptide backbone and c-terminal modifications |
| WO2010132954A1 (en) | 2009-05-21 | 2010-11-25 | Oral Health Australia Pty Ltd | Method of treating periodontal disease by administering antagonists of par-2 |
| JP5675821B2 (ja) * | 2009-09-23 | 2015-02-25 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレート | Ｔｏｌｌ様受容体モジュレーター及びその使用 |
| AU2011207441A1 (en) | 2010-01-22 | 2012-08-09 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
| US10627412B2 (en) * | 2010-03-17 | 2020-04-21 | Kagoshima University | Periodontal-disease-specific peptide, and treatment and diagnosis of periodontal disease using same |
| US10039802B2 (en) * | 2011-06-22 | 2018-08-07 | Apellis Pharmaceuticals, Inc. | Methods of treating chronic disorders with complement inhibitors |
| WO2013036778A2 (en) * | 2011-09-07 | 2013-03-14 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with improved pharmacokinetic properties |
| US9579360B2 (en) * | 2012-06-20 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
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| EP2863949B1 (en) | 2019-01-23 |
| US20130344082A1 (en) | 2013-12-26 |
| AU2013277217A1 (en) | 2015-01-22 |
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| AU2013277217B2 (en) | 2018-03-08 |
| EP2863949A4 (en) | 2016-03-02 |
| CA2877299A1 (en) | 2013-12-27 |
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