CA2876762A1 - Stabilized gp120 - Google Patents
Stabilized gp120 Download PDFInfo
- Publication number
- CA2876762A1 CA2876762A1 CA2876762A CA2876762A CA2876762A1 CA 2876762 A1 CA2876762 A1 CA 2876762A1 CA 2876762 A CA2876762 A CA 2876762A CA 2876762 A CA2876762 A CA 2876762A CA 2876762 A1 CA2876762 A1 CA 2876762A1
- Authority
- CA
- Canada
- Prior art keywords
- polypeptide
- hiv
- isolated polypeptide
- stabilized
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
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- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16171—Demonstrated in vivo effect
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
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- Public Health (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Hematology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
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- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201261661050P | 2012-06-18 | 2012-06-18 | |
| US61/661,050 | 2012-06-18 | ||
| PCT/EP2013/062553 WO2013189901A1 (en) | 2012-06-18 | 2013-06-17 | Stabilized gp120 |
Publications (1)
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| CA2876762A1 true CA2876762A1 (en) | 2013-12-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2876762A Abandoned CA2876762A1 (en) | 2012-06-18 | 2013-06-17 | Stabilized gp120 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20150183835A1 (https=) |
| EP (1) | EP2861249A1 (https=) |
| JP (1) | JP2015521592A (https=) |
| KR (1) | KR20150023735A (https=) |
| CN (1) | CN104619338A (https=) |
| AU (1) | AU2013279456A1 (https=) |
| CA (1) | CA2876762A1 (https=) |
| IL (1) | IL235898A0 (https=) |
| IN (1) | IN2014KN02740A (https=) |
| MX (1) | MX2014014682A (https=) |
| RU (1) | RU2015101081A (https=) |
| SG (1) | SG11201407995RA (https=) |
| WO (1) | WO2013189901A1 (https=) |
| ZA (1) | ZA201408840B (https=) |
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| WO2016037154A1 (en) * | 2014-09-04 | 2016-03-10 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Recombinant hiv-1 envelope proteins and their use |
| RU2745373C2 (ru) * | 2014-09-23 | 2021-03-24 | БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. | Рекомбинантные вакцины от fmdv и их применение |
| EP3069730A3 (en) * | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US10808011B2 (en) | 2016-03-09 | 2020-10-20 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Recombinant HIV-1 envelope proteins and their use |
| EP4613776A3 (en) | 2016-10-21 | 2025-11-26 | Altor BioScience Corporation | Multimeric il-15-based molecules |
| WO2019079337A1 (en) | 2017-10-16 | 2019-04-25 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | RECOMBINANT HIV-1 ENVELOPE PROTEINS AND THEIR USE |
| CN109851664A (zh) * | 2017-11-30 | 2019-06-07 | 清华大学 | 一种基于抗体反向表位设计的蛋白质及其在制备抗艾滋病病毒疫苗中的应用 |
| MX2020013621A (es) | 2018-06-19 | 2021-03-25 | Nantcell Inc | Composiciones y metodos de tratamiento de vih. |
| WO2021249013A1 (en) * | 2020-06-10 | 2021-12-16 | Sichuan Clover Biopharmaceuticals, Inc. | Vaccine compositions, methods, and uses thereof |
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|---|---|---|---|---|
| FR2786488B1 (fr) * | 1998-11-27 | 2003-04-25 | Orstom | Mutants de la gp120 et leurs applications biologiques |
| HK1046911A1 (zh) * | 1999-06-25 | 2003-01-30 | Progenics Pharmaceuticals, Inc. | 经稳定的病毒外膜蛋白质及其使用 |
| JP2010536885A (ja) * | 2007-08-24 | 2010-12-02 | ノバルティス アーゲー | Ｖ３ループに改変を有するｈｉｖｅｎｖタンパク質 |
| CA2774636C (en) * | 2009-09-25 | 2019-05-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to hiv-1 and their use |
-
2013
- 2013-06-17 WO PCT/EP2013/062553 patent/WO2013189901A1/en not_active Ceased
- 2013-06-17 CN CN201380032027.2A patent/CN104619338A/zh active Pending
- 2013-06-17 CA CA2876762A patent/CA2876762A1/en not_active Abandoned
- 2013-06-17 AU AU2013279456A patent/AU2013279456A1/en not_active Abandoned
- 2013-06-17 IN IN2740KON2014 patent/IN2014KN02740A/en unknown
- 2013-06-17 US US14/408,466 patent/US20150183835A1/en not_active Abandoned
- 2013-06-17 JP JP2015516648A patent/JP2015521592A/ja active Pending
- 2013-06-17 EP EP13729364.3A patent/EP2861249A1/en not_active Withdrawn
- 2013-06-17 KR KR20157000850A patent/KR20150023735A/ko not_active Withdrawn
- 2013-06-17 RU RU2015101081A patent/RU2015101081A/ru not_active Application Discontinuation
- 2013-06-17 SG SG11201407995RA patent/SG11201407995RA/en unknown
- 2013-06-17 MX MX2014014682A patent/MX2014014682A/es unknown
-
2014
- 2014-11-25 IL IL235898A patent/IL235898A0/en unknown
- 2014-12-02 ZA ZA2014/08840A patent/ZA201408840B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201407995RA (en) | 2015-01-29 |
| IL235898A0 (en) | 2015-01-29 |
| JP2015521592A (ja) | 2015-07-30 |
| IN2014KN02740A (https=) | 2015-05-08 |
| ZA201408840B (en) | 2016-08-31 |
| EP2861249A1 (en) | 2015-04-22 |
| WO2013189901A1 (en) | 2013-12-27 |
| KR20150023735A (ko) | 2015-03-05 |
| MX2014014682A (es) | 2015-03-04 |
| CN104619338A (zh) | 2015-05-13 |
| AU2013279456A1 (en) | 2014-12-18 |
| RU2015101081A (ru) | 2016-08-10 |
| US20150183835A1 (en) | 2015-07-02 |
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