CA2875710C - Molecular malignancy in melanocytic lesions - Google Patents
Molecular malignancy in melanocytic lesions Download PDFInfo
- Publication number
- CA2875710C CA2875710C CA2875710A CA2875710A CA2875710C CA 2875710 C CA2875710 C CA 2875710C CA 2875710 A CA2875710 A CA 2875710A CA 2875710 A CA2875710 A CA 2875710A CA 2875710 C CA2875710 C CA 2875710C
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- Prior art keywords
- mir
- sample
- expression
- biomarkers
- melanoma
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261663428P | 2012-06-22 | 2012-06-22 | |
| US61/663,428 | 2012-06-22 | ||
| PCT/US2013/047354 WO2013192616A1 (en) | 2012-06-22 | 2013-06-24 | Molecular malignancy in melanocytic lesions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2875710A1 CA2875710A1 (en) | 2013-12-27 |
| CA2875710C true CA2875710C (en) | 2021-06-29 |
Family
ID=49769469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2875710A Active CA2875710C (en) | 2012-06-22 | 2013-06-24 | Molecular malignancy in melanocytic lesions |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9758829B2 (https=) |
| EP (1) | EP2864500B1 (https=) |
| JP (1) | JP6366580B2 (https=) |
| CN (1) | CN104603291B (https=) |
| AU (1) | AU2013277971B2 (https=) |
| CA (1) | CA2875710C (https=) |
| WO (1) | WO2013192616A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014149629A1 (en) * | 2013-03-15 | 2014-09-25 | Htg Molecular Diagnostics, Inc. | Subtyping lung cancers |
| US11021752B2 (en) * | 2013-03-15 | 2021-06-01 | Myriad Genetics, Inc. | Genes and gene signatures for diagnosis and treatment of melanoma |
| WO2014182330A1 (en) | 2013-05-06 | 2014-11-13 | Hitachi Chemical Company Ltd | Devices and methods for capturing target molecules |
| JP6496899B2 (ja) * | 2014-07-01 | 2019-04-10 | 公立大学法人福島県立医科大学 | 浸潤性髄膜腫判別用試薬、及びその判別方法 |
| EP3164508B1 (en) * | 2014-07-02 | 2023-06-07 | Myriad myPath, LLC | Genes and gene signatures for diagnosis and treatment of melanoma |
| EP3218521B1 (en) * | 2014-11-12 | 2019-12-25 | Hitachi Chemical Co., Ltd. | Method for diagnosing organ injury |
| WO2016152352A1 (ja) * | 2015-03-20 | 2016-09-29 | 国立大学法人名古屋大学 | メラノーマ特異的バイオマーカー及びその利用 |
| GB2544834A (en) * | 2015-06-09 | 2017-05-31 | Waters Technologies Corp | Profile diagnositcs in personalized dermatology, dermatopathology and cosmetics |
| GB2565238A (en) * | 2015-06-09 | 2019-02-06 | Waters Technologies Corp | Molecular diagnostics in personalized dermatology, dermatopathology and cosmetics |
| CN107636678B (zh) * | 2015-06-29 | 2021-12-14 | 北京市商汤科技开发有限公司 | 用于预测图像样本的属性的方法和设备 |
| DE112016003948T5 (de) | 2015-08-31 | 2018-05-09 | City Of Sapporo | Molekulare verfahren zum beurteilen einer urothelialen erkrankung |
| JP7354099B2 (ja) * | 2017-10-03 | 2023-10-02 | ジェネシーク ピーティーワイ リミテッド | マイクロｒｎａ遺伝子発現を使用して黒色腫を診断し、病期分類し、モニタリングする方法 |
| US20210012214A1 (en) * | 2018-03-29 | 2021-01-14 | Nec Corporation | Learning apparatus, learning method, and computer-readable recording medium |
| CN108537005B (zh) * | 2018-04-03 | 2019-04-02 | 福州大学 | 一种基于BPSO-KNN模型的关键lncRNA预测方法 |
| JP7526100B2 (ja) | 2018-05-31 | 2024-07-31 | バークレー ライツ，インコーポレイテッド | マイクロ流体デバイスによる微小物体の自動検出及び特徴付け |
| US11017896B2 (en) * | 2018-06-28 | 2021-05-25 | Case Western Reserve University | Radiomic features of prostate bi-parametric magnetic resonance imaging (BPMRI) associate with decipher score |
| FR3085825B1 (fr) | 2018-09-14 | 2021-07-16 | Fermentalg | Huile de microorganismes riche en acide docosahexaenoique |
| FR3085962B1 (fr) | 2018-09-14 | 2021-06-18 | Fermentalg | Procede d'extracton d'une huile riche en pufa |
| TW202018727A (zh) | 2018-11-09 | 2020-05-16 | 財團法人工業技術研究院 | 整體式學習預測方法與系統 |
| CN112513891B (zh) * | 2019-01-02 | 2025-12-05 | 松下电器（美国）知识产权公司 | 信息处理装置、信息处理方法及记录介质 |
| CN114693646B (zh) * | 2022-03-31 | 2023-04-11 | 中山大学中山眼科中心 | 一种基于深度学习的角膜内皮细胞活性因子的分析方法 |
| JP7806660B2 (ja) * | 2022-11-11 | 2026-01-27 | コニカミノルタ株式会社 | 検出方法 |
| WO2024108191A1 (en) * | 2022-11-18 | 2024-05-23 | University Of Virginia Patent Foundation | Machine learning approach to predicting lymph node metastases |
| CN117625632A (zh) * | 2024-01-22 | 2024-03-01 | 中国医学科学院北京协和医院 | 肌萎缩侧索硬化症的SQSTM1的p.L382CfsTer13突变致病基因及其应用 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| WO1985001051A1 (en) | 1983-09-02 | 1985-03-14 | Molecular Biosystems, Inc. | Oligonucleotide polymeric support system |
| GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
| US5219727A (en) | 1989-08-21 | 1993-06-15 | Hoffmann-Laroche Inc. | Quantitation of nucleic acids using the polymerase chain reaction |
| US5554501A (en) | 1992-10-29 | 1996-09-10 | Beckman Instruments, Inc. | Biopolymer synthesis using surface activated biaxially oriented polypropylene |
| EP0700521B1 (en) | 1993-05-28 | 2003-06-04 | Baylor College Of Medicine | Method and mass spectrometer for desorption and ionization of analytes |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| EP0758403B1 (en) | 1994-05-05 | 1998-06-24 | Beckman Instruments, Inc. | Oligonucleotide repeat arrays |
| US5866330A (en) | 1995-09-12 | 1999-02-02 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
| US5736330A (en) | 1995-10-11 | 1998-04-07 | Luminex Corporation | Method and compositions for flow cytometric determination of DNA sequences |
| US5716784A (en) | 1996-02-05 | 1998-02-10 | The Perkin-Elmer Corporation | Fluorescence detection assay for homogeneous PCR hybridization systems |
| US6449562B1 (en) | 1996-10-10 | 2002-09-10 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| US5985567A (en) | 1997-08-15 | 1999-11-16 | Beckman Coulter, Inc. | Hybridization detection by pretreating bound single-stranded probes |
| US20030096232A1 (en) | 1997-12-19 | 2003-05-22 | Kris Richard M. | High throughput assay system |
| US6232066B1 (en) | 1997-12-19 | 2001-05-15 | Neogen, Inc. | High throughput assay system |
| US6238869B1 (en) | 1997-12-19 | 2001-05-29 | High Throughput Genomics, Inc. | High throughput assay system |
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| EP1410011B1 (en) | 2001-06-18 | 2011-03-23 | Rosetta Inpharmatics LLC | Diagnosis and prognosis of breast cancer patients |
| US7171311B2 (en) | 2001-06-18 | 2007-01-30 | Rosetta Inpharmatics Llc | Methods of assigning treatment to breast cancer patients |
| US7473767B2 (en) | 2001-07-03 | 2009-01-06 | The Institute For Systems Biology | Methods for detection and quantification of analytes in complex mixtures |
| JP2007527247A (ja) | 2004-03-05 | 2007-09-27 | ロゼッタ インファーマティクス エルエルシー | 臨床的基準および情報提供性遺伝子セットの組合せを使用する乳癌患者の分類 |
| BRPI0512587A (pt) | 2004-06-25 | 2007-09-18 | Veridex Llc | processo e reagentes para detecção de melanoma |
| CN101687022B (zh) | 2007-03-26 | 2016-09-07 | 莱顿大学医学中心附属莱顿教学医院 | Prame衍生的肽以及包括该肽的免疫原组合物 |
| US20080268451A1 (en) | 2007-03-30 | 2008-10-30 | Bruce Seligmann | Measurement of an insoluble analyte in a sample |
| WO2009062199A1 (en) | 2007-11-09 | 2009-05-14 | Fox Chase Cancer Center | EGFR/NEDD9/TGF-β LNTERACTOME AND METHODS OF USE THEREOF FOR THE IDENTIFICATION OF AGENTS HAVING EFFICACY IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS |
| WO2009099905A2 (en) * | 2008-02-01 | 2009-08-13 | Memorial Health Inc. | Molecular signatures and biomarkers associated with melanoma and methods of use thereof |
| CN102089444A (zh) | 2008-05-14 | 2011-06-08 | 德玛泰克国际公司 | 利用核酸分析方法来诊断黑素瘤和太阳能雀斑 |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| WO2012031008A2 (en) * | 2010-08-31 | 2012-03-08 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| EP2619332A4 (en) | 2010-09-22 | 2014-04-16 | Dave S B Hoon | DIRECT BLOOD ASSAY TO DETECT MICROARN CIRCULATING IN PATIENTS WITH CANCER |
| ES2597032T3 (es) | 2011-05-04 | 2017-01-13 | HTG Molecular Diagnostics, Inc | Mejoras en un ensayo cuantitativo de protección contra la nucleasa (qNPA) y secuenciación (qNPS) |
| AU2012316129B2 (en) | 2011-09-28 | 2017-10-05 | Htg Molecular Diagnostics, Inc. | Methods of co-detecting mRNA and small non-coding RNA |
-
2013
- 2013-06-24 US US14/405,739 patent/US9758829B2/en active Active
- 2013-06-24 JP JP2015518637A patent/JP6366580B2/ja not_active Expired - Fee Related
- 2013-06-24 EP EP13806645.1A patent/EP2864500B1/en active Active
- 2013-06-24 WO PCT/US2013/047354 patent/WO2013192616A1/en not_active Ceased
- 2013-06-24 AU AU2013277971A patent/AU2013277971B2/en active Active
- 2013-06-24 CN CN201380045664.3A patent/CN104603291B/zh active Active
- 2013-06-24 CA CA2875710A patent/CA2875710C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN104603291A (zh) | 2015-05-06 |
| EP2864500B1 (en) | 2018-08-22 |
| AU2013277971B2 (en) | 2018-11-15 |
| CN104603291B (zh) | 2018-04-06 |
| WO2013192616A1 (en) | 2013-12-27 |
| EP2864500A1 (en) | 2015-04-29 |
| CA2875710A1 (en) | 2013-12-27 |
| US9758829B2 (en) | 2017-09-12 |
| JP6366580B2 (ja) | 2018-08-01 |
| AU2013277971A1 (en) | 2015-01-29 |
| US20150176072A1 (en) | 2015-06-25 |
| JP2015521483A (ja) | 2015-07-30 |
| EP2864500A4 (en) | 2016-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20180517 |
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| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 12TH ANNIV.) - STANDARD Year of fee payment: 12 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250430 |
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Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250430 |