CA2875146C - Bioactive agent delivery devices and methods of making and using the same - Google Patents

Bioactive agent delivery devices and methods of making and using the same Download PDF

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Publication number
CA2875146C
CA2875146C CA2875146A CA2875146A CA2875146C CA 2875146 C CA2875146 C CA 2875146C CA 2875146 A CA2875146 A CA 2875146A CA 2875146 A CA2875146 A CA 2875146A CA 2875146 C CA2875146 C CA 2875146C
Authority
CA
Canada
Prior art keywords
microdevice
reservoirs
poly
bioactive agent
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2875146A
Other languages
English (en)
French (fr)
Other versions
CA2875146A1 (en
Inventor
Tejal A. Desai
Hariharasudhan D. CHIRRA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of CA2875146A1 publication Critical patent/CA2875146A1/en
Application granted granted Critical
Publication of CA2875146C publication Critical patent/CA2875146C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/0035—Multiple processes, e.g. applying a further resist layer on an already in a previously step, processed pattern or textured surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097—Medicinal compositions released by microdevices, e.g. microelectromechanical systems [MEMS], microdevices comprising chips or microdevices on silicon
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/26—Processing photosensitive materials; Apparatus therefor
    • G03F7/40—Treatment after imagewise removal, e.g. baking

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2875146A 2012-05-30 2013-05-24 Bioactive agent delivery devices and methods of making and using the same Expired - Fee Related CA2875146C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261653119P 2012-05-30 2012-05-30
US61/653,119 2012-05-30
PCT/US2013/042710 WO2013181107A1 (en) 2012-05-30 2013-05-24 Bioactive agent delivery devices and methods of making and using the same

Publications (2)

Publication Number Publication Date
CA2875146A1 CA2875146A1 (en) 2013-12-05
CA2875146C true CA2875146C (en) 2022-03-22

Family

ID=49673842

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2875146A Expired - Fee Related CA2875146C (en) 2012-05-30 2013-05-24 Bioactive agent delivery devices and methods of making and using the same

Country Status (8)

Country Link
US (1) US9878137B2 (enExample)
EP (1) EP2856259B1 (enExample)
JP (1) JP6336442B2 (enExample)
CN (1) CN104412160B (enExample)
BR (1) BR112014029760A2 (enExample)
CA (1) CA2875146C (enExample)
IN (1) IN2014DN10765A (enExample)
WO (1) WO2013181107A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2768492C2 (ru) 2011-11-18 2022-03-24 Ридженерон Фармасьютикалз, Инк. Полимерные белковые микрочастицы
US9463177B2 (en) 2012-09-10 2016-10-11 The Regents Of The University Of California Compounds and methods for modulating vascular injury
ES2647791T3 (es) 2013-12-16 2017-12-26 Massachusetts Institute Of Technology Formulaciones de sales enriquecidas en micronutrientes
CA2933867A1 (en) 2013-12-16 2015-06-25 Massachusetts Institute Of Technology Micromolded or 3-d printed pulsatile release vaccine formulations
WO2016100136A1 (en) * 2014-12-15 2016-06-23 The Regents Of The University Of California Nanowire-coated microdevice and method of making and using the same
CA3001346A1 (en) 2015-10-16 2017-04-20 Regeneron Pharmaceuticals, Inc. Stable protein compositions
US10429387B2 (en) * 2016-07-27 2019-10-01 Universiteit Tweate Simple and affordable method for immuophenotyping using a microfluidic chip sample preparation with image cytometry
US20190076631A1 (en) * 2017-09-13 2019-03-14 Massachusetts Institute Of Technology Microdevices with complex geometries
JP7287032B2 (ja) * 2019-03-20 2023-06-06 株式会社リコー シート、シート積層体、医薬品、シートの製造方法、及びシート積層体の製造方法
AU2021270750B2 (en) 2020-05-13 2024-06-13 Massachusetts Institute Of Technology Compositions of polymeric microdevices and their use in cancer immunotherapy
CN113804667A (zh) * 2021-09-23 2021-12-17 上海交通大学 一种新型可膨胀生物样本的水凝胶及其应用
US20240077474A1 (en) * 2022-09-06 2024-03-07 Seagate Technology Llc System and methods for positioning biomaterial on a substrate

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
WO1996041236A1 (en) * 1995-06-07 1996-12-19 The Regents Of The University Of California Therapeutic microdevices and methods of making and using same
US5567271A (en) 1995-07-26 1996-10-22 Chartered Semiconductor Manufacturing Pte Ltd Oxygen reactive ion etch (RIE) plasma method for removing oxidized organic residues from semiconductor substrates
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
KR100397860B1 (ko) 1997-09-22 2003-12-18 카가쿠기쥬쯔죠 킨조쿠자이료 기쥬쯔켄큐죠 반응성이온에칭법및그장치
US6355270B1 (en) * 1999-01-11 2002-03-12 The Regents Of The University Of California Particles for oral delivery of peptides and proteins
US6770441B2 (en) 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
US7351376B1 (en) * 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
CA2432438C (en) 2001-01-09 2011-04-26 Microchips, Inc. Flexible microchip devices for ophthalmic and other applications
US20020115224A1 (en) * 2001-02-16 2002-08-22 Ulrich Rudel Method for the preparation of optical (bio)chemical sensor devices
WO2004006840A2 (en) * 2002-07-12 2004-01-22 The Regents Of The University Of California Three dimensional cell patterned bioploymer scaffolds and method of making the same
AU2005302484A1 (en) * 2004-10-28 2006-05-11 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
EP2319558B1 (en) * 2006-03-14 2014-05-21 University Of Southern California Mems device for delivery of therapeutic agents
WO2008109886A1 (en) 2007-03-08 2008-09-12 The Regents Of The University Of California Topographically engineered structures and methods for using the same in regenerative medicine applications
ES2558544T3 (es) 2007-03-16 2016-02-05 The Regents Of The University Of California Implantes médicos revestidos en la superficie de nanoestructura y métodos de empleo de los mismos
AU2010246067B2 (en) 2009-05-04 2016-07-07 Eyepoint Pharmaceuticals Us, Inc. Porous silicon drug-eluting particles

Also Published As

Publication number Publication date
EP2856259A4 (en) 2015-12-30
CA2875146A1 (en) 2013-12-05
JP2015519366A (ja) 2015-07-09
EP2856259B1 (en) 2018-12-26
CN104412160A (zh) 2015-03-11
US20150119807A1 (en) 2015-04-30
BR112014029760A2 (pt) 2017-06-27
JP6336442B2 (ja) 2018-06-06
US9878137B2 (en) 2018-01-30
EP2856259A1 (en) 2015-04-08
CN104412160B (zh) 2019-09-20
IN2014DN10765A (enExample) 2015-09-04
WO2013181107A1 (en) 2013-12-05

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Legal Events

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EEER Examination request

Effective date: 20180502

MKLA Lapsed

Effective date: 20220524