CA2871127A1 - Composition for preventing headaches - Google Patents
Composition for preventing headaches Download PDFInfo
- Publication number
- CA2871127A1 CA2871127A1 CA2871127A CA2871127A CA2871127A1 CA 2871127 A1 CA2871127 A1 CA 2871127A1 CA 2871127 A CA2871127 A CA 2871127A CA 2871127 A CA2871127 A CA 2871127A CA 2871127 A1 CA2871127 A1 CA 2871127A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- cysteine
- glutathione
- active agents
- acetaldehyde
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 206010019233 Headaches Diseases 0.000 title description 16
- 231100000869 headache Toxicity 0.000 title description 13
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims abstract description 84
- 239000013543 active substance Substances 0.000 claims abstract description 56
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- 108010024636 Glutathione Proteins 0.000 claims abstract description 42
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- 238000000034 method Methods 0.000 claims abstract description 17
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- 229930195710 D‐cysteine Natural products 0.000 claims abstract description 11
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims abstract description 11
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Classifications
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20125570A FI129157B (en) | 2012-05-28 | 2012-05-28 | Composition for use in reducing the incidence of or preventing severe headaches |
| FI20125570 | 2012-05-28 | ||
| PCT/FI2013/050582 WO2013178880A1 (en) | 2012-05-28 | 2013-05-28 | Composition for preventing headaches |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2871127A1 true CA2871127A1 (en) | 2013-12-05 |
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ID=49672530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2871127A Abandoned CA2871127A1 (en) | 2012-05-28 | 2013-05-28 | Composition for preventing headaches |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10092534B2 (enExample) |
| EP (1) | EP2854792B1 (enExample) |
| JP (2) | JP2015518038A (enExample) |
| KR (1) | KR20150016382A (enExample) |
| CN (2) | CN108042520A (enExample) |
| AU (1) | AU2013269448B2 (enExample) |
| BR (1) | BR112014029165A2 (enExample) |
| CA (1) | CA2871127A1 (enExample) |
| DK (1) | DK2854792T3 (enExample) |
| ES (1) | ES2922243T3 (enExample) |
| FI (1) | FI129157B (enExample) |
| HK (2) | HK1208362A1 (enExample) |
| HU (1) | HUE059234T2 (enExample) |
| IL (1) | IL235972B (enExample) |
| JO (1) | JOP20130157B1 (enExample) |
| MX (1) | MX2014014609A (enExample) |
| PL (1) | PL2854792T3 (enExample) |
| PT (1) | PT2854792T (enExample) |
| RU (1) | RU2698196C2 (enExample) |
| TW (1) | TWI660726B (enExample) |
| WO (1) | WO2013178880A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI128082B (en) * | 2014-09-15 | 2019-09-13 | Biohit Oyj | Preparations for the treatment and prevention of alcohol redness and alcohol-induced hypersensitivity reactions |
| FI127823B (en) * | 2015-03-06 | 2019-03-15 | Biohit Oyj | Composition for preventing hangover symptoms |
| WO2017004396A1 (en) * | 2015-06-30 | 2017-01-05 | Nucorplabs, Inc. | Chewable composition to deliver gsh |
| BE1025644B1 (fr) * | 2017-10-13 | 2019-05-15 | Synapharm Industrial Synthesis | Compose pour le traitement d'une maladie ou d'un trouble du systeme nerveux central chez un sujet en stimulant et/ou en restaurant la plasticite neuronale |
| CN112804888A (zh) * | 2018-11-02 | 2021-05-14 | 雀巢产品有限公司 | 含有缓冲盐和氨基酸的粉末，此类粉末向营养产品的重构，以及使用此类营养产品的方法 |
| CA3137407A1 (fr) | 2019-05-16 | 2020-11-19 | Synapharm Industrial Synthesis | Compound and composition for use in the treatment of premenstrual syndrome and/or premenstrual dysphoric disorder |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4496548A (en) | 1983-02-04 | 1985-01-29 | Moldowan Mervin J | Composition and method for reducing hangover |
| US4528295A (en) | 1983-08-15 | 1985-07-09 | Boris Tabakoff | Composition and method for reducing blood acetaldehyde levels |
| US5202354A (en) | 1986-02-18 | 1993-04-13 | Takeda Chemical Industries, Ltd. | Composition and method for reducing acetaldehyde toxicity |
| JPH02193926A (ja) * | 1989-01-20 | 1990-07-31 | Lion Corp | 胃腸薬 |
| US6294520B1 (en) | 1989-03-27 | 2001-09-25 | Albert T. Naito | Material for passage through the blood-brain barrier |
| US5906811A (en) | 1997-06-27 | 1999-05-25 | Thione International, Inc. | Intra-oral antioxidant preparations |
| US5922346A (en) | 1997-12-01 | 1999-07-13 | Thione International, Inc. | Antioxidant preparation |
| US6726939B1 (en) * | 2000-03-22 | 2004-04-27 | Kyoungsik Pak | Composition and method for reducing blood pressure, alleviating or eliminating angina pectoris and headaches, and enhancing skin and hair |
| US6502038B1 (en) * | 2000-06-30 | 2002-12-31 | Exxonmobil Upstream Research Company | Method for non-hyperbolic moveout analysis of seismic data |
| FI121528B (fi) * | 2000-10-30 | 2010-12-31 | Biohit Oyj | Farmaseuttinen koostumus syöpään sairastumisen riskin vähentämiseen paikallisesti sitomalla asetaldehydi syljessä, mahalaukussa tai paksusuolessa |
| WO2006037848A1 (en) | 2004-10-08 | 2006-04-13 | Biohit Oyj | Method and preparation for binding aldehydes in saliva |
| WO2005077464A1 (en) | 2004-02-17 | 2005-08-25 | Matuschka-Greinffenclau Markus | Alcohol metabolism moderating composition |
| JP2006130488A (ja) * | 2004-11-02 | 2006-05-25 | Kazutoshi Igarashi | 新無機多孔体を利用した有害分子を吸着分解できる基剤 |
| FI122914B (fi) * | 2005-04-01 | 2012-08-31 | Biohit Oyj | Elintarvikekoostumus asetaldehydin sitomiseksi suussa ja ruoansulatuskanavassa ja menetelmä koostumuksen valmistamiseksi |
| US7611739B2 (en) | 2006-01-06 | 2009-11-03 | Amerilab Technologies, Inc. | Method of using guava extract and composition including guava extract |
| FI20060501A7 (fi) * | 2006-05-22 | 2007-11-23 | Biohit Oyj | Koostumus ja menetelmä asetaldehydin sitomiseksi mahalaukussa |
| JP2006328079A (ja) * | 2006-07-26 | 2006-12-07 | T Langeland Bjorn | 特定の金属酵素を刺激する組成物 |
| US20080057110A1 (en) | 2006-08-29 | 2008-03-06 | Alexander Skirpa | Compositions for alcoholic beverages and methods of producing thereof |
| US20080075710A1 (en) | 2006-09-25 | 2008-03-27 | Liquid Potions Llc | Herbal composition for treating hangovers |
| FI20070705A7 (fi) * | 2007-09-14 | 2009-06-02 | Biohit Oyj | Asetaldehydin sitominen suussa ja mahalaukussa |
| CN101862332A (zh) * | 2009-04-20 | 2010-10-20 | 兰章华 | 防治过量饮酒对人体损伤的组合物及其制备方法和用途 |
| JP2011057674A (ja) | 2009-09-11 | 2011-03-24 | Omnica Gmbh | コエンザイムｑ−１０と抗酸化剤とを含む組成物 |
| EP2374448A1 (en) * | 2010-04-06 | 2011-10-12 | Labtec GmbH | Oral film formulation |
| WO2012027603A2 (en) * | 2010-08-26 | 2012-03-01 | Clarity Products, Limited Liability Company | Therapeutic consumable compositions for reduction of facial flush effect incident to alcohol consumption in persons with deficient activity of the aldehyde dehydrogenase gene-aldh2 |
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2012
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2013
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- 2013-05-27 TW TW102118677A patent/TWI660726B/zh active
- 2013-05-28 CN CN201711384347.0A patent/CN108042520A/zh active Pending
- 2013-05-28 BR BR112014029165A patent/BR112014029165A2/pt not_active Application Discontinuation
- 2013-05-28 PL PL13796555.4T patent/PL2854792T3/pl unknown
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- 2013-05-28 KR KR1020147036794A patent/KR20150016382A/ko not_active Ceased
- 2013-05-28 CA CA2871127A patent/CA2871127A1/en not_active Abandoned
- 2013-05-28 AU AU2013269448A patent/AU2013269448B2/en active Active
- 2013-05-28 DK DK13796555.4T patent/DK2854792T3/da active
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- 2013-05-28 RU RU2014143120A patent/RU2698196C2/ru active
- 2013-05-28 PT PT137965554T patent/PT2854792T/pt unknown
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- 2013-05-28 JP JP2015514547A patent/JP2015518038A/ja active Pending
- 2013-05-28 MX MX2014014609A patent/MX2014014609A/es unknown
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2014
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2018
- 2018-08-20 HK HK18110629.8A patent/HK1251161A1/zh unknown
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2019
- 2019-02-26 JP JP2019032510A patent/JP2019089842A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2854792A1 (en) | 2015-04-08 |
| JP2015518038A (ja) | 2015-06-25 |
| TWI660726B (zh) | 2019-06-01 |
| RU2698196C2 (ru) | 2019-08-23 |
| WO2013178880A1 (en) | 2013-12-05 |
| HK1208362A1 (en) | 2016-03-04 |
| AU2013269448A1 (en) | 2014-11-13 |
| CN104427983A (zh) | 2015-03-18 |
| IL235972A0 (en) | 2015-01-29 |
| FI129157B (en) | 2021-08-13 |
| RU2014143120A (ru) | 2016-07-20 |
| BR112014029165A2 (pt) | 2017-06-27 |
| US10092534B2 (en) | 2018-10-09 |
| KR20150016382A (ko) | 2015-02-11 |
| PL2854792T3 (pl) | 2022-10-03 |
| FI20125570A7 (fi) | 2013-11-29 |
| CN108042520A (zh) | 2018-05-18 |
| EP2854792A4 (en) | 2015-11-18 |
| HUE059234T2 (hu) | 2022-10-28 |
| IL235972B (en) | 2019-10-31 |
| HK1251161A1 (zh) | 2019-01-25 |
| FI20125570L (fi) | 2013-11-29 |
| ES2922243T3 (es) | 2022-09-12 |
| US20150132275A1 (en) | 2015-05-14 |
| JP2019089842A (ja) | 2019-06-13 |
| PT2854792T (pt) | 2022-07-13 |
| AU2013269448B2 (en) | 2016-02-11 |
| DK2854792T3 (da) | 2022-07-11 |
| EP2854792B1 (en) | 2022-06-15 |
| TW201408286A (zh) | 2014-03-01 |
| JOP20130157B1 (ar) | 2021-08-17 |
| MX2014014609A (es) | 2015-02-12 |
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