CA2867804C - Target windows for isotope production systems - Google Patents
Target windows for isotope production systems Download PDFInfo
- Publication number
- CA2867804C CA2867804C CA2867804A CA2867804A CA2867804C CA 2867804 C CA2867804 C CA 2867804C CA 2867804 A CA2867804 A CA 2867804A CA 2867804 A CA2867804 A CA 2867804A CA 2867804 C CA2867804 C CA 2867804C
- Authority
- CA
- Canada
- Prior art keywords
- foil
- foil member
- target
- members
- isotope production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 56
- 239000011888 foil Substances 0.000 claims abstract description 252
- 239000000463 material Substances 0.000 claims abstract description 47
- 239000002245 particle Substances 0.000 claims description 60
- 230000001133 acceleration Effects 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 13
- 229910052758 niobium Inorganic materials 0.000 claims description 12
- 239000010955 niobium Substances 0.000 claims description 12
- GUCVJGMIXFAOAE-UHFFFAOYSA-N niobium atom Chemical compound [Nb] GUCVJGMIXFAOAE-UHFFFAOYSA-N 0.000 claims description 12
- 238000007789 sealing Methods 0.000 claims description 8
- 229910052782 aluminium Inorganic materials 0.000 claims description 7
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 7
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 6
- 229910052715 tantalum Inorganic materials 0.000 claims description 6
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 claims description 6
- 239000010936 titanium Substances 0.000 claims description 6
- 229910052719 titanium Inorganic materials 0.000 claims description 6
- 238000012546 transfer Methods 0.000 claims description 6
- 229910000531 Co alloy Inorganic materials 0.000 claims description 5
- 238000002844 melting Methods 0.000 claims description 5
- 230000008018 melting Effects 0.000 claims description 5
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 2
- 229910052802 copper Inorganic materials 0.000 claims description 2
- 239000010949 copper Substances 0.000 claims description 2
- 239000007769 metal material Substances 0.000 claims 21
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 4
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 4
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims 2
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims 2
- 229910052804 chromium Inorganic materials 0.000 claims 2
- 239000011651 chromium Substances 0.000 claims 2
- 229910052742 iron Inorganic materials 0.000 claims 2
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 claims 2
- 229910052750 molybdenum Inorganic materials 0.000 claims 2
- 239000011733 molybdenum Substances 0.000 claims 2
- 229910052759 nickel Inorganic materials 0.000 claims 2
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 claims 2
- 229910052721 tungsten Inorganic materials 0.000 claims 2
- 239000010937 tungsten Substances 0.000 claims 2
- 239000004020 conductor Substances 0.000 claims 1
- 239000013077 target material Substances 0.000 description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 238000000034 method Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 6
- 238000000605 extraction Methods 0.000 description 6
- 230000002285 radioactive effect Effects 0.000 description 6
- 229910045601 alloy Inorganic materials 0.000 description 5
- 239000000956 alloy Substances 0.000 description 5
- 230000032258 transport Effects 0.000 description 5
- 238000002059 diagnostic imaging Methods 0.000 description 4
- 239000001307 helium Substances 0.000 description 4
- 229910052734 helium Inorganic materials 0.000 description 4
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 4
- 150000002500 ions Chemical class 0.000 description 4
- 230000005684 electric field Effects 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- -1 hydrogen ions Chemical class 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 235000006506 Brasenia schreberi Nutrition 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 230000017525 heat dissipation Effects 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 238000013160 medical therapy Methods 0.000 description 2
- 238000009206 nuclear medicine Methods 0.000 description 2
- 238000002600 positron emission tomography Methods 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 238000012879 PET imaging Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229960004210 ammonia n-13 Drugs 0.000 description 1
- QGZKDVFQNNGYKY-BJUDXGSMSA-N ammonia-(13)N Chemical compound [13NH3] QGZKDVFQNNGYKY-BJUDXGSMSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H6/00—Targets for producing nuclear reactions
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- High Energy & Nuclear Physics (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Particle Accelerators (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/436,222 US9894746B2 (en) | 2012-03-30 | 2012-03-30 | Target windows for isotope systems |
| US13/436,222 | 2012-03-30 | ||
| PCT/US2013/027709 WO2013172909A1 (en) | 2012-03-30 | 2013-02-26 | Target windows for isotope production systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2867804A1 CA2867804A1 (en) | 2013-11-21 |
| CA2867804C true CA2867804C (en) | 2020-06-16 |
Family
ID=49170845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2867804A Active CA2867804C (en) | 2012-03-30 | 2013-02-26 | Target windows for isotope production systems |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9894746B2 (enExample) |
| EP (1) | EP2832191B1 (enExample) |
| JP (1) | JP6352897B2 (enExample) |
| CN (1) | CN104206027B (enExample) |
| CA (1) | CA2867804C (enExample) |
| WO (1) | WO2013172909A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4615169A3 (en) | 2014-05-15 | 2025-12-10 | Mayo Foundation for Medical Education and Research | Solution target for cyclotron production of radiometals |
| CN104010431B (zh) * | 2014-05-15 | 2016-04-06 | 上海原子科兴药业有限公司 | 一种fdg靶系统 |
| US9961756B2 (en) * | 2014-10-07 | 2018-05-01 | General Electric Company | Isotope production target chamber including a cavity formed from a single sheet of metal foil |
| US9991013B2 (en) * | 2015-06-30 | 2018-06-05 | General Electric Company | Production assemblies and removable target assemblies for isotope production |
| US10340051B2 (en) | 2016-02-16 | 2019-07-02 | General Electric Company | Radioisotope production system and method for controlling the same |
| JP6752590B2 (ja) * | 2016-02-29 | 2020-09-09 | 日本メジフィジックス株式会社 | ターゲット装置および放射性核種製造装置 |
| US10595392B2 (en) * | 2016-06-17 | 2020-03-17 | General Electric Company | Target assembly and isotope production system having a grid section |
| US10354771B2 (en) * | 2016-11-10 | 2019-07-16 | General Electric Company | Isotope production system having a target assembly with a graphene target sheet |
| US20180322972A1 (en) * | 2017-05-04 | 2018-11-08 | General Electric Company | System and method for making a solid target within a production chamber of a target assembly |
| US10109383B1 (en) * | 2017-08-15 | 2018-10-23 | General Electric Company | Target assembly and nuclide production system |
| CA3225455A1 (en) | 2018-06-06 | 2019-12-12 | Phoenix Neutron Imaging Llc | Ion beam target assemblies for neutron generation |
| US11315700B2 (en) | 2019-05-09 | 2022-04-26 | Strangis Radiopharmacy Consulting and Technology | Method and apparatus for production of radiometals and other radioisotopes using a particle accelerator |
| EP3885771B1 (en) * | 2020-03-26 | 2024-11-27 | F. Hoffmann-La Roche AG | Method and system to re-identify carriers on a laboratory transport system |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4364898A (en) | 1980-10-10 | 1982-12-21 | The United States Of America As Represented By The United States Department Of Energy | Method for the preparation of radon-211 |
| JPS6319836Y2 (enExample) | 1981-03-12 | 1988-06-02 | ||
| JPS57151600U (enExample) | 1981-03-18 | 1982-09-22 | ||
| JPS58117100U (ja) | 1982-02-03 | 1983-08-10 | 三菱電機株式会社 | ビ−ム取出し窓 |
| BE1005530A4 (fr) | 1991-11-22 | 1993-09-28 | Ion Beam Applic Sa | Cyclotron isochrone |
| BE1009669A3 (fr) | 1995-10-06 | 1997-06-03 | Ion Beam Applic Sa | Methode d'extraction de particules chargees hors d'un cyclotron isochrone et dispositif appliquant cette methode. |
| SE513191C2 (sv) | 1998-09-29 | 2000-07-24 | Gems Pet Systems Ab | Snabbkoppling |
| SE513192C2 (sv) | 1998-09-29 | 2000-07-24 | Gems Pet Systems Ab | Förfarande och system för HF-styrning |
| SE513193C2 (sv) | 1998-09-29 | 2000-07-24 | Gems Pet Systems Ab | Integralt strålningsskydd |
| CA2450484C (en) | 2001-06-13 | 2008-11-04 | Stefan K. Zeisler | Apparatus and method for generating 18f-fluoride by ion beams |
| EP1509925B1 (en) | 2002-05-21 | 2008-10-01 | Duke University | Batch target and method for producing radionuclide |
| EP1569243A1 (en) | 2004-02-20 | 2005-08-31 | Ion Beam Applications S.A. | Target device for producing a radioisotope |
| JP2008501612A (ja) | 2004-06-08 | 2008-01-24 | トライアンフ，オペレーティング アズ ア ジョイント ヴェンチャー バイ ザ ガバナーズ オブ ザ ユニバーシティ オブ アルバータ，ザ ユニバーシティ オブ ブリティッシュ コロンビア，カールトン | 複合セラミック対象物の形成方法 |
| US7786442B2 (en) | 2004-06-18 | 2010-08-31 | General Electric Company | Method and apparatus for ion source positioning and adjustment |
| US20060062342A1 (en) * | 2004-09-17 | 2006-03-23 | Cyclotron Partners, L.P. | Method and apparatus for the production of radioisotopes |
| US7122966B2 (en) | 2004-12-16 | 2006-10-17 | General Electric Company | Ion source apparatus and method |
| US20070040115A1 (en) * | 2005-08-05 | 2007-02-22 | Publicover Julia G | Method for calibrating particle beam energy |
| JP4099187B2 (ja) | 2005-09-30 | 2008-06-11 | 株式会社日立製作所 | 放射性同位元素製造装置、及びターゲットのリサイクル方法 |
| US7466085B2 (en) | 2007-04-17 | 2008-12-16 | Advanced Biomarker Technologies, Llc | Cyclotron having permanent magnets |
| US7476883B2 (en) | 2006-05-26 | 2009-01-13 | Advanced Biomarker Technologies, Llc | Biomarker generator system |
| EP2171724A1 (en) * | 2007-06-22 | 2010-04-07 | Advanced Applied Physics Solutions, Inc. | Higher pressure, modular target system for radioisotope production |
| US20090052628A1 (en) * | 2007-08-24 | 2009-02-26 | Governors Of The Universty Of Alberta | Target foil for use in the production of [18f] using a particle accelerator |
| EP2146555A1 (en) | 2008-07-18 | 2010-01-20 | Ion Beam Applications S.A. | Target apparatus for production of radioisotopes |
| US8106570B2 (en) | 2009-05-05 | 2012-01-31 | General Electric Company | Isotope production system and cyclotron having reduced magnetic stray fields |
| US8153997B2 (en) | 2009-05-05 | 2012-04-10 | General Electric Company | Isotope production system and cyclotron |
| US8106370B2 (en) | 2009-05-05 | 2012-01-31 | General Electric Company | Isotope production system and cyclotron having a magnet yoke with a pump acceptance cavity |
| US8374306B2 (en) | 2009-06-26 | 2013-02-12 | General Electric Company | Isotope production system with separated shielding |
| US9693443B2 (en) | 2010-04-19 | 2017-06-27 | General Electric Company | Self-shielding target for isotope production systems |
-
2012
- 2012-03-30 US US13/436,222 patent/US9894746B2/en active Active
-
2013
- 2013-02-26 CN CN201380018275.1A patent/CN104206027B/zh active Active
- 2013-02-26 WO PCT/US2013/027709 patent/WO2013172909A1/en not_active Ceased
- 2013-02-26 EP EP13762606.5A patent/EP2832191B1/en active Active
- 2013-02-26 CA CA2867804A patent/CA2867804C/en active Active
- 2013-02-26 JP JP2015503213A patent/JP6352897B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015512517A (ja) | 2015-04-27 |
| CA2867804A1 (en) | 2013-11-21 |
| EP2832191B1 (en) | 2020-06-03 |
| CN104206027B (zh) | 2020-04-21 |
| CN104206027A (zh) | 2014-12-10 |
| US20130259180A1 (en) | 2013-10-03 |
| US9894746B2 (en) | 2018-02-13 |
| WO2013172909A1 (en) | 2013-11-21 |
| EP2832191A1 (en) | 2015-02-04 |
| JP6352897B2 (ja) | 2018-07-04 |
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| CA2867804C (en) | Target windows for isotope production systems | |
| CA2796935C (en) | Self-shielding target for isotope production systems | |
| RU2769259C2 (ru) | Сборка мишени и система производства нуклидов | |
| US20160141062A1 (en) | Target body for an isotope production system and method of using the same | |
| US10595392B2 (en) | Target assembly and isotope production system having a grid section | |
| US9894747B2 (en) | Radio-frequency electrode and cyclotron configured to reduce radiation exposure | |
| US10354771B2 (en) | Isotope production system having a target assembly with a graphene target sheet | |
| JP7396949B2 (ja) | ターゲット装置及び放射性核種の製造装置 | |
| Bruno et al. | The beam absorbers of the 3 MeV H-Test Facility at CERN |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20171219 |