CA2867489A1 - Methods and composition for sequencing modified nucleic acids - Google Patents
Methods and composition for sequencing modified nucleic acids Download PDFInfo
- Publication number
- CA2867489A1 CA2867489A1 CA2867489A CA2867489A CA2867489A1 CA 2867489 A1 CA2867489 A1 CA 2867489A1 CA 2867489 A CA2867489 A CA 2867489A CA 2867489 A CA2867489 A CA 2867489A CA 2867489 A1 CA2867489 A1 CA 2867489A1
- Authority
- CA
- Canada
- Prior art keywords
- sequence
- data
- nucleic acid
- sequencing
- nucleic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261617999P | 2012-03-30 | 2012-03-30 | |
US61/617,999 | 2012-03-30 | ||
US201261721206P | 2012-11-01 | 2012-11-01 | |
US201261721339P | 2012-11-01 | 2012-11-01 | |
US201361789354P | 2013-03-15 | 2013-03-15 | |
US201361799237P | 2013-03-15 | 2013-03-15 | |
PCT/US2013/032816 WO2013148400A1 (en) | 2012-03-30 | 2013-03-18 | Methods and composition for sequencing modified nucleic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2867489A1 true CA2867489A1 (en) | 2013-10-03 |
Family
ID=49261113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2867489A Abandoned CA2867489A1 (en) | 2012-03-30 | 2013-03-18 | Methods and composition for sequencing modified nucleic acids |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2831283A4 (de) |
AU (1) | AU2013240166A1 (de) |
CA (1) | CA2867489A1 (de) |
WO (1) | WO2013148400A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9290800B2 (en) | 2013-03-15 | 2016-03-22 | Pacific Biosciences Of California, Inc. | Targeted rolling circle amplification |
JP6573899B2 (ja) * | 2013-11-17 | 2019-09-11 | クアンタム−エスアイ インコーポレイテッドQuantum−Si Incorporated | 分子をプローブし、検出し、及び分析するための、外部光源を備えた集積デバイス |
CA2964937A1 (en) * | 2014-10-22 | 2016-04-28 | Ibis Biosciences, Inc. | Bacterial epigenomic analysis |
US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
WO2016100049A1 (en) | 2014-12-18 | 2016-06-23 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
EP3459115A4 (de) | 2016-05-16 | 2020-04-08 | Agilome, Inc. | Graphen-fet-vorrichtungen, systeme und verfahren zur verwendung davon zur sequenzierung von nukleinsäuren |
BR112018074572B1 (pt) * | 2016-06-01 | 2024-02-27 | Quantum-Si Incorporated | Métodos de identificação de nucleotídeos e para calibrar um instrumento de sequenciamento, meio de armazenamento legível em computador não transitório, dispositivo e instrumento de sequenciamento |
EP3366780B1 (de) | 2017-02-23 | 2020-05-06 | Siemens Healthcare GmbH | Sequenzanalyse von einzelmolekülen und hochempfindliche methylierungsanalyse zur gewebespezifischen analyse |
JP7304852B2 (ja) * | 2017-11-03 | 2023-07-07 | ガーダント ヘルス, インコーポレイテッド | 脱アミノ化に誘導される配列エラーの補正 |
US11538556B2 (en) | 2018-01-26 | 2022-12-27 | Quantum-Si Incorporated | Machine learning enabled pulse and base calling for sequencing devices |
WO2019226689A1 (en) | 2018-05-22 | 2019-11-28 | Axbio Inc. | Methods, systems, and compositions for nucleic acid sequencing |
US20230295608A1 (en) * | 2022-03-17 | 2023-09-21 | Regeneron Pharmaceuticals, Inc. | Methods for Characterization of Viral Genome Using Base Modifications |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0711303B2 (de) | 1993-07-30 | 2009-06-10 | Affymax, Inc. | Biotinylierung von proteinen |
US5795782A (en) | 1995-03-17 | 1998-08-18 | President & Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
JP2002521064A (ja) | 1998-07-30 | 2002-07-16 | ソレックサ リミテッド | アレイ生体分子およびシークエンシングにおけるその使用 |
US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
US6917726B2 (en) | 2001-09-27 | 2005-07-12 | Cornell Research Foundation, Inc. | Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes |
WO2005014506A2 (en) | 2003-08-06 | 2005-02-17 | Department Of Science & Technology (Dst) | A process for the manufacture of a bio-release fertiliser of an anionic micro nutrient viz molibdenum |
US20060046258A1 (en) * | 2004-02-27 | 2006-03-02 | Lapidus Stanley N | Applications of single molecule sequencing |
US7399614B2 (en) | 2004-06-30 | 2008-07-15 | Applera Corporation | 5-methylcytosine detection, compositions and methods therefor |
JP2008513782A (ja) | 2004-09-17 | 2008-05-01 | パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド | 分子解析のための装置及び方法 |
US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
US7805081B2 (en) | 2005-08-11 | 2010-09-28 | Pacific Biosciences Of California, Inc. | Methods and systems for monitoring multiple optical signals from a single source |
US7405281B2 (en) | 2005-09-29 | 2008-07-29 | Pacific Biosciences Of California, Inc. | Fluorescent nucleotide analogs and uses therefor |
JP2009511862A (ja) | 2005-09-30 | 2009-03-19 | パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド | 反応性表面、基質および同表面、基質の製造および使用方法 |
US7998717B2 (en) | 2005-12-02 | 2011-08-16 | Pacific Biosciences Of California, Inc. | Mitigation of photodamage in analytical reactions |
CA2633524A1 (en) | 2005-12-22 | 2007-07-05 | Pacific Biosciences Of California, Inc. | Polymerases for nucleotide analogue incorporation |
EP3936857B1 (de) | 2006-09-01 | 2023-06-21 | Pacific Biosciences Of California, Inc. | Substrate, systeme und verfahren zur analyse von materialien |
US20080277595A1 (en) | 2007-05-10 | 2008-11-13 | Pacific Biosciences Of California, Inc. | Highly multiplexed confocal detection systems and methods of using same |
CA2689626C (en) * | 2007-06-06 | 2016-10-25 | Pacific Biosciences Of California, Inc. | Methods and processes for calling bases in sequence by incorporation methods |
CN101802220B (zh) | 2007-07-26 | 2013-07-31 | 加利福尼亚太平洋生物科学股份有限公司 | 分子冗余测序法 |
US8252911B2 (en) | 2008-02-12 | 2012-08-28 | Pacific Biosciences Of California, Inc. | Compositions and methods for use in analytical reactions |
US8652781B2 (en) | 2008-02-12 | 2014-02-18 | Pacific Biosciences Of California, Inc. | Cognate sampling kinetics |
AU2009223702B2 (en) | 2008-03-13 | 2013-08-22 | Pacific Biosciences Of California, Inc. | Labeled reactants and their uses |
US7973146B2 (en) | 2008-03-26 | 2011-07-05 | Pacific Biosciences Of California, Inc. | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing |
JP2011515102A (ja) | 2008-03-28 | 2011-05-19 | パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド | 核酸シーケンシング用組成物及び方法 |
WO2009120374A2 (en) | 2008-03-28 | 2009-10-01 | Pacific Biosciences Of California, Inc. | Methods and compositions for nucleic acid sample preparation |
US8143030B2 (en) | 2008-09-24 | 2012-03-27 | Pacific Biosciences Of California, Inc. | Intermittent detection during analytical reactions |
CA2720247C (en) * | 2008-03-31 | 2020-07-14 | Pacific Biosciences Of California, Inc. | Single molecule loading methods and compositions |
WO2009145820A2 (en) | 2008-03-31 | 2009-12-03 | Pacific Biosciences Of California, Inc. | Generation of modified polymerases for improved accuracy in single molecule sequencing |
CA3063032A1 (en) | 2008-09-16 | 2010-03-25 | Pacific Biosciences Of California, Inc. | Substrates and optical systems and methods of use thereof |
US8481264B2 (en) | 2008-09-19 | 2013-07-09 | Pacific Biosciences Of California, Inc. | Immobilized nucleic acid complexes for sequence analysis |
US8370079B2 (en) | 2008-11-20 | 2013-02-05 | Pacific Biosciences Of California, Inc. | Algorithms for sequence determination |
US9175338B2 (en) | 2008-12-11 | 2015-11-03 | Pacific Biosciences Of California, Inc. | Methods for identifying nucleic acid modifications |
EP2370598B1 (de) * | 2008-12-11 | 2017-02-15 | Pacific Biosciences Of California, Inc. | Klassifizierung von nukleinsäuretemplaten |
JP5439822B2 (ja) | 2009-01-15 | 2014-03-12 | 独立行政法人物質・材料研究機構 | Ni基単結晶超合金 |
US9017937B1 (en) | 2009-04-10 | 2015-04-28 | Pacific Biosciences Of California, Inc. | Nanopore sequencing using ratiometric impedance |
AU2010245304B2 (en) | 2009-04-27 | 2015-06-04 | Pacific Biosciences Of California, Inc. | Real-time sequencing methods and systems |
WO2011103421A1 (en) * | 2010-02-18 | 2011-08-25 | Shuber Anthony P | Compositions and methods for treating cancer |
US20130138358A1 (en) | 2010-02-24 | 2013-05-30 | Pacific Biosciences Of California, Inc. | Algorithms for sequence determination |
US9165109B2 (en) | 2010-02-24 | 2015-10-20 | Pacific Biosciences Of California, Inc. | Sequence assembly and consensus sequence determination |
-
2013
- 2013-03-18 WO PCT/US2013/032816 patent/WO2013148400A1/en active Application Filing
- 2013-03-18 AU AU2013240166A patent/AU2013240166A1/en not_active Abandoned
- 2013-03-18 CA CA2867489A patent/CA2867489A1/en not_active Abandoned
- 2013-03-18 EP EP13769322.2A patent/EP2831283A4/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2013240166A1 (en) | 2014-10-30 |
EP2831283A4 (de) | 2015-11-04 |
WO2013148400A1 (en) | 2013-10-03 |
EP2831283A1 (de) | 2015-02-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |
Effective date: 20190319 |