CA2866782C - Polymeric composite materials with antimicrobial and biodegradable properties and uses thereof - Google Patents

Polymeric composite materials with antimicrobial and biodegradable properties and uses thereof Download PDF

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Publication number
CA2866782C
CA2866782C CA2866782A CA2866782A CA2866782C CA 2866782 C CA2866782 C CA 2866782C CA 2866782 A CA2866782 A CA 2866782A CA 2866782 A CA2866782 A CA 2866782A CA 2866782 C CA2866782 C CA 2866782C
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Canada
Prior art keywords
pvpi
alginate
iodine
films
glycerol
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CA2866782A
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English (en)
French (fr)
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CA2866782A1 (en
Inventor
Athanasia Athanasiou
Ilker S. Bayer
Ioannis Liakos
Loris Rizzello
Roberto Cingolani
Stefania Sabella
Pier Paolo Pompa
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Italian Institute of Technology
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Publication of CA2866782A1 publication Critical patent/CA2866782A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/202—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with halogen atoms, e.g. triclosan, povidone-iodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Composite Materials (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CA2866782A 2012-03-21 2013-03-21 Polymeric composite materials with antimicrobial and biodegradable properties and uses thereof Active CA2866782C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000258A ITTO20120258A1 (it) 2012-03-21 2012-03-21 Materiali compositi polimerici con proprieta' antimicrobiche e biodegradabili e loro usi.
ITTO2012A000258 2012-03-21
PCT/IB2013/052245 WO2013140362A1 (en) 2012-03-21 2013-03-21 Polymeric composite materials with antimicrobial and biodegradable properties and uses thereof

Publications (2)

Publication Number Publication Date
CA2866782A1 CA2866782A1 (en) 2013-09-26
CA2866782C true CA2866782C (en) 2020-03-10

Family

ID=46584198

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2866782A Active CA2866782C (en) 2012-03-21 2013-03-21 Polymeric composite materials with antimicrobial and biodegradable properties and uses thereof

Country Status (6)

Country Link
US (1) US9931444B2 (enExample)
EP (1) EP2827912B1 (enExample)
JP (1) JP6157582B2 (enExample)
CA (1) CA2866782C (enExample)
IT (1) ITTO20120258A1 (enExample)
WO (1) WO2013140362A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102429862B (zh) * 2011-11-29 2013-05-01 江苏德达医药科技有限公司 一种聚维酮碘眼用缓释滴眼液
KR101592144B1 (ko) 2015-06-19 2016-02-04 고려대학교 산학협력단 요오드 캡슐, 이의 제조방법 및 이를 포함하는 소금
CN108670948A (zh) * 2018-05-04 2018-10-19 江西新天地药业有限公司 一种纳米级微囊单分子聚维酮碘溶液及其制备方法
GB2588442A (en) 2019-10-24 2021-04-28 Io Cyte Ltd Antimicrobial material
GB2588440A (en) 2019-10-24 2021-04-28 Io Cyte Ltd Swellable antimicrobial fibre
GB2588439A (en) 2019-10-24 2021-04-28 Io Cyte Ltd Swellable antimicrobial fibre
CN111671966B (zh) * 2020-06-17 2022-01-28 浙江理工大学 一种医用缝合线及其制备方法与应用
WO2023067449A1 (en) * 2021-10-18 2023-04-27 FREMSLIFE S.r.l. Biomedical device for the treatment of ulcers or lesions

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4373519A (en) * 1981-06-26 1983-02-15 Minnesota Mining And Manufacturing Company Composite wound dressing
US4478853A (en) * 1982-05-17 1984-10-23 S. C. Johnson & Son, Inc. Skin conditioning composition
HUT38684A (en) * 1983-11-29 1986-06-30 Avtex Fibers Inc Fibrous material of germicide activity
JP3254013B2 (ja) * 1991-09-10 2002-02-04 ジョンソン・アンド・ジョンソン・メディカル・インコーポレイテッド 包帯材料およびその製造方法
JPH11100323A (ja) * 1997-09-29 1999-04-13 Taiho Yakuhin Kogyo Kk 外用医薬製剤
CN1100543C (zh) * 1998-03-27 2003-02-05 李勤耕 聚维酮碘膜剂
JP2000038342A (ja) * 1998-05-18 2000-02-08 Kyowa Yakuhin Kogyo Kk 褥瘡・損傷皮膚修復用製剤
JP4841733B2 (ja) * 2001-01-31 2011-12-21 三笠製薬株式会社 創傷治療用製剤
BR0102637A (pt) * 2001-05-17 2003-02-25 Johnson & Johnson Ind Com Curativo adesivo
JP4712380B2 (ja) * 2002-07-26 2011-06-29 三笠製薬株式会社 外用剤
JP5047797B2 (ja) * 2004-09-30 2012-10-10 コヴァロン・テクノロジーズ・インコーポレーテッド 非接着性の弾性ゼラチンマトリックス
TW200637564A (en) * 2004-12-27 2006-11-01 Kowa Co Orally disintegrable solid preparation comprising povidone-iodine
SE530184C2 (sv) * 2005-12-23 2008-03-18 Kjell Stenberg Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater
JP2007332063A (ja) * 2006-06-14 2007-12-27 Kowa Co ポビドンヨードを含有する口腔内崩壊型固形製剤
US20110171284A1 (en) * 2010-01-11 2011-07-14 Gilman Miles E Povidone-iodine and sucrose wound healing dressing
CN102429862B (zh) * 2011-11-29 2013-05-01 江苏德达医药科技有限公司 一种聚维酮碘眼用缓释滴眼液

Also Published As

Publication number Publication date
ITTO20120258A1 (it) 2013-09-22
EP2827912B1 (en) 2020-08-26
EP2827912A1 (en) 2015-01-28
JP2015516189A (ja) 2015-06-11
CA2866782A1 (en) 2013-09-26
US20150050234A1 (en) 2015-02-19
WO2013140362A1 (en) 2013-09-26
US9931444B2 (en) 2018-04-03
JP6157582B2 (ja) 2017-07-05

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