CA2847188C - Non-small cell lung cancer biomarkers and uses thereof - Google Patents

Non-small cell lung cancer biomarkers and uses thereof Download PDF

Info

Publication number
CA2847188C
CA2847188C CA2847188A CA2847188A CA2847188C CA 2847188 C CA2847188 C CA 2847188C CA 2847188 A CA2847188 A CA 2847188A CA 2847188 A CA2847188 A CA 2847188A CA 2847188 C CA2847188 C CA 2847188C
Authority
CA
Canada
Prior art keywords
biomarkers
biomarker
individual
nsclc
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2847188A
Other languages
English (en)
French (fr)
Other versions
CA2847188A1 (en
Inventor
Michael Riel-Mehan
Alex A.E. Stewart
Rachel M. Ostroff
Stephen Alaric Williams
Edward N. Brody
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Somalogic Operating Co Inc
Original Assignee
Somalogic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Inc filed Critical Somalogic Inc
Priority to CA3006793A priority Critical patent/CA3006793C/en
Priority to CA3064363A priority patent/CA3064363C/en
Publication of CA2847188A1 publication Critical patent/CA2847188A1/en
Application granted granted Critical
Publication of CA2847188C publication Critical patent/CA2847188C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2847188A 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof Active CA2847188C (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA3006793A CA3006793C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA3064363A CA3064363C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/057499 WO2013062515A2 (en) 2011-10-24 2011-10-24 Lung cancer biomarkers and uses thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CA3006793A Division CA3006793C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA3064363A Division CA3064363C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Publications (2)

Publication Number Publication Date
CA2847188A1 CA2847188A1 (en) 2013-05-02
CA2847188C true CA2847188C (en) 2020-02-18

Family

ID=48168748

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2847188A Active CA2847188C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA3064363A Active CA3064363C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA3006793A Active CA3006793C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA3064363A Active CA3064363C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA3006793A Active CA3006793C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Country Status (15)

Country Link
EP (1) EP2771692B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP5986638B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR101921945B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (2) CN103890586B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2011378427B8 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR112014006432B8 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (3) CA2847188C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2674318T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (2) IL231426A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2014CN01787A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX355416B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ621733A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SG (1) SG11201400375SA (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2013062515A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA201401476B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG186953A1 (en) 2010-07-09 2013-02-28 Somalogic Inc Lung cancer biomarkers and uses thereof
WO2014179959A1 (en) * 2013-05-09 2014-11-13 The Procter & Gamble Company Method and system for assessing health condition
ES3014093T3 (en) 2014-07-30 2025-04-16 Harvard College Method for determining nucleic acids
CN104263723B (zh) * 2014-09-15 2017-06-06 南京医科大学 一种与原发性肺癌辅助诊断相关的低频高外显性遗传标志物及其应用
WO2016094330A2 (en) * 2014-12-08 2016-06-16 20/20 Genesystems, Inc Methods and machine learning systems for predicting the liklihood or risk of having cancer
JP6857185B2 (ja) * 2015-09-11 2021-04-14 アプタマー サイエンス インコーポレイテッドAptamer Sciences Inc. 非小細胞肺癌診断用タンパク質バイオマーカーパネル及びこれを用いた非小細胞肺癌診断方法
KR102086935B1 (ko) * 2015-11-05 2020-03-09 비지아이 션전 폐 선암종을 검출하기 위한 생체마커 및 그의 사용
EP3828272B9 (en) * 2016-03-18 2023-12-27 Caris Science, Inc. Method of enrichment of oligonucleotide probes
KR101853118B1 (ko) * 2016-09-02 2018-04-30 주식회사 바이오인프라생명과학 피험체의 폐암 진단을 위한 복합 바이오마커군, 이를 이용하는 폐암 진단용 키트, 복합 바이오마커군의 정보를 이용하는 방법 및 이를 수행하는 컴퓨팅 시스템
WO2018089445A1 (en) * 2016-11-08 2018-05-17 President And Fellows Of Harvard College Matrix imprinting and clearing
CN110402394B (zh) * 2017-03-01 2024-04-26 豪夫迈·罗氏有限公司 用于将关于分析物的存在的生物样品进行分类的系统和方法
WO2018218150A1 (en) 2017-05-26 2018-11-29 President And Fellows Of Harvard College Systems and methods for high-throughput image-based screening
CN109116023B (zh) * 2018-06-14 2021-06-04 郑州大学第一附属医院 一种肺癌标志物抗-mmp12自身抗体及其应用
CN109470859A (zh) * 2018-11-04 2019-03-15 华东医院 一种外泌体蛋白作为鉴别肺结节良恶性标志物及其应用
EP3671210A1 (en) * 2018-12-21 2020-06-24 Biosystems International KFT Lung cancer protein epitomic biomarkers
CN113711313A (zh) * 2019-02-15 2021-11-26 佰欧迪塞克斯公司 用于识别手术后处于高复发风险的早期nsclc患者的预测性测试
CN110473167B (zh) * 2019-07-09 2022-06-17 哈尔滨工程大学 一种基于深度学习的尿沉渣图像识别系统及方法
CN112892619B (zh) * 2019-12-04 2022-07-15 香港城市大学深圳研究院 弧形边缘截面的pdms母模、微流控阀和芯片及其制备
KR102613772B1 (ko) * 2021-02-02 2023-12-14 제노마인(주) 폐암 혈액 바이오마커의 검출 방법 및 키트

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335170B1 (en) * 1999-02-22 2002-01-01 Torben F. Orntoft Gene expression in bladder tumors
US6596503B1 (en) 2000-08-18 2003-07-22 East Carolina University Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
US20090297500A1 (en) * 2004-08-10 2009-12-03 Oncotherapy Science, Inc. NON-SMALL CELL LUNG CANCER-RELATED GENE, ANLN, AND ITS INTERACTION WITH RhoA
JP2009502115A (ja) * 2005-07-27 2009-01-29 オンコセラピー・サイエンス株式会社 小細胞肺癌の診断方法
WO2007015947A2 (en) 2005-07-29 2007-02-08 Bayer Healthcare Llc Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies
US8445198B2 (en) 2005-12-01 2013-05-21 Medical Prognosis Institute Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
US8014957B2 (en) * 2005-12-15 2011-09-06 Fred Hutchinson Cancer Research Center Genes associated with progression and response in chronic myeloid leukemia and uses thereof
EP2090665A2 (en) * 2006-10-20 2009-08-19 Exiqon A/S Novel human microRNAs associated with cancer
GB0803192D0 (en) * 2008-02-22 2008-04-02 Mubio Products Bv SCLC biomarker panel
GB2478441B (en) * 2008-09-09 2013-03-27 Somalogic Inc Lung cancer biomarkers and uses thereof
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2011109440A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
EP3029158A1 (en) 2008-11-17 2016-06-08 Veracyte, Inc. Methods and compositions of molecular profiling for disease diagnostics
US20110236903A1 (en) * 2008-12-04 2011-09-29 Mcclelland Michael Materials and methods for determining diagnosis and prognosis of prostate cancer
WO2011100472A1 (en) * 2010-02-10 2011-08-18 The Regents Of The University Of California Salivary transcriptomic and proteomic biomarkers for breast cancer detection
WO2011127219A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease

Also Published As

Publication number Publication date
NZ621733A (en) 2015-05-29
BR112014006432B1 (pt) 2021-04-06
CA3006793A1 (en) 2013-05-02
BR112014006432B8 (pt) 2022-10-25
IL231426A0 (en) 2014-04-30
KR20140082840A (ko) 2014-07-02
AU2011378427A1 (en) 2013-05-16
WO2013062515A3 (en) 2014-04-17
CA3064363A1 (en) 2013-05-02
CA3064363C (en) 2022-05-17
AU2011378427B2 (en) 2015-07-16
EP2771692B1 (en) 2018-04-18
ES2674318T3 (es) 2018-06-28
ZA201401476B (en) 2016-06-29
CN103890586B (zh) 2016-06-29
MX355416B (es) 2018-04-18
SG11201400375SA (en) 2014-04-28
EP2771692A4 (en) 2015-08-26
CN103890586A (zh) 2014-06-25
AU2011378427B8 (en) 2015-08-27
CN106168624B (zh) 2018-03-13
MX2014004860A (es) 2014-05-27
CA2847188A1 (en) 2013-05-02
CA3006793C (en) 2020-02-18
JP5986638B2 (ja) 2016-09-06
KR101921945B1 (ko) 2018-11-26
EP2771692A2 (en) 2014-09-03
AU2011378427A8 (en) 2015-08-27
WO2013062515A2 (en) 2013-05-02
CN106168624A (zh) 2016-11-30
BR112014006432A2 (pt) 2017-04-04
IN2014CN01787A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2015-05-29
IL252163A0 (en) 2017-07-31
JP2015501154A (ja) 2015-01-15
IL231426A (en) 2017-06-29

Similar Documents

Publication Publication Date Title
US11041866B2 (en) Pancreatic cancer biomarkers and uses thereof
CA2847188C (en) Non-small cell lung cancer biomarkers and uses thereof
DK2340506T3 (en) Biomarkers of lung cancer and uses thereof
CA2809282C (en) Mesothelioma biomarkers and uses thereof
US20120101002A1 (en) Lung Cancer Biomarkers and Uses Thereof
US20120143805A1 (en) Cancer Biomarkers and Uses Thereof
WO2011031344A1 (en) Cancer biomarkers and uses thereof
WO2011043840A1 (en) Cancer biomarkers and uses thereof
WO2013028807A2 (en) Renal cell carcinoma biomarkers and uses thereof
EP2350917A1 (en) Ovarian cancer biomarkers and uses thereof
US20220065872A1 (en) Lung Cancer Biomarkers and Uses Thereof
HK1196429B (en) Lung cancer biomarkers and uses thereof
HK1196429A (en) Lung cancer biomarkers and uses thereof
HK1153834B (en) Lung cancer biomarkers and uses thereof

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20161021