CA2842392C - Improved baculovirus expression systems - Google Patents
Improved baculovirus expression systems Download PDFInfo
- Publication number
- CA2842392C CA2842392C CA2842392A CA2842392A CA2842392C CA 2842392 C CA2842392 C CA 2842392C CA 2842392 A CA2842392 A CA 2842392A CA 2842392 A CA2842392 A CA 2842392A CA 2842392 C CA2842392 C CA 2842392C
- Authority
- CA
- Canada
- Prior art keywords
- recombinant
- baculovirus
- genome
- gene
- recombinant baculovirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14051—Methods of production or purification of viral material
- C12N2710/14052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14144—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161512142P | 2011-07-27 | 2011-07-27 | |
| US61/512,142 | 2011-07-27 | ||
| PCT/EP2012/064843 WO2013014294A2 (en) | 2011-07-27 | 2012-07-27 | Improved baculovirus expression systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2842392A1 CA2842392A1 (en) | 2013-01-31 |
| CA2842392C true CA2842392C (en) | 2020-09-15 |
Family
ID=46640007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2842392A Expired - Fee Related CA2842392C (en) | 2011-07-27 | 2012-07-27 | Improved baculovirus expression systems |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10480010B2 (enEXAMPLES) |
| EP (1) | EP2737071B1 (enEXAMPLES) |
| JP (1) | JP6122430B2 (enEXAMPLES) |
| CN (1) | CN103748229A (enEXAMPLES) |
| BR (1) | BR112014001863A2 (enEXAMPLES) |
| CA (1) | CA2842392C (enEXAMPLES) |
| DK (1) | DK2737071T3 (enEXAMPLES) |
| ES (1) | ES2623780T3 (enEXAMPLES) |
| IN (1) | IN2014CN00688A (enEXAMPLES) |
| WO (1) | WO2013014294A2 (enEXAMPLES) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10577627B2 (en) | 2014-06-09 | 2020-03-03 | Voyager Therapeutics, Inc. | Chimeric capsids |
| HK1243922A1 (zh) | 2014-11-05 | 2018-07-27 | Voyager Therapeutics, Inc. | 用於治疗帕金森病的aadc多核苷酸 |
| CA2967367C (en) | 2014-11-14 | 2023-05-16 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| US10570395B2 (en) | 2014-11-14 | 2020-02-25 | Voyager Therapeutics, Inc. | Modulatory polynucleotides |
| EP3230441A4 (en) | 2014-12-12 | 2018-10-03 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scaav |
| US11299751B2 (en) | 2016-04-29 | 2022-04-12 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| US11326182B2 (en) | 2016-04-29 | 2022-05-10 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| CN117904112A (zh) | 2016-05-18 | 2024-04-19 | 沃雅戈治疗公司 | 调节性多核苷酸 |
| SG11201809643UA (en) | 2016-05-18 | 2018-12-28 | Voyager Therapeutics Inc | Compositions and methods of treating huntington's disease |
| JP2019531787A (ja) | 2016-08-30 | 2019-11-07 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 生物医学的ターゲティング及びデリバリーの方法並びにそれを実行するための装置及びシステム |
| US11752181B2 (en) | 2017-05-05 | 2023-09-12 | Voyager Therapeutics, Inc. | Compositions and methods of treating Huntington's disease |
| CN110913866A (zh) | 2017-05-05 | 2020-03-24 | 沃雅戈治疗公司 | 治疗肌萎缩性侧索硬化(als)的组合物和方法 |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| CN111132626B (zh) | 2017-07-17 | 2024-01-30 | 沃雅戈治疗公司 | 轨迹阵列引导系统 |
| MX2020001187A (es) | 2017-08-03 | 2020-10-05 | Voyager Therapeutics Inc | Composiciones y métodos para la administración de virus adenoasociados. |
| AU2018338728B2 (en) | 2017-09-29 | 2025-01-02 | Centre National De La Recherche Scientifique (Cnrs) | Rescue of central and peripheral neurological phenotype of Friedreich's Ataxia by intravenous delivery |
| US11434502B2 (en) | 2017-10-16 | 2022-09-06 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (ALS) |
| EP4454654A3 (en) | 2017-10-16 | 2025-02-19 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
| BR112020023082A2 (pt) | 2018-05-15 | 2021-02-09 | Voyager Therapeutics, Inc. | composições e métodos para o tratamento de doença de parkinson |
| CA3114621A1 (en) | 2018-09-28 | 2020-04-02 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| EP3867389A1 (en) * | 2018-10-15 | 2021-08-25 | Voyager Therapeutics, Inc. | Expression vectors for large-scale production of raav in the baculovirus/sf9 system |
| CN109609552B (zh) * | 2018-12-28 | 2020-04-14 | 中国科学院武汉物理与数学研究所 | 重组腺相关病毒的制备方法、系统及重组杆粒 |
| AU2020223149B2 (en) | 2019-02-15 | 2025-05-22 | Sangamo Therapeutics, Inc. | Compositions and methods for producing recombinant AAV |
| KR102272651B1 (ko) * | 2019-03-28 | 2021-07-02 | 충북대학교 산학협력단 | 외래단백질의 발현량과 발현시간이 증대된 배큘로바이러스 |
| AU2020302861A1 (en) * | 2019-06-26 | 2022-02-24 | Virovek, Inc. | Baculovirus expression system |
| US20220154223A1 (en) | 2020-10-15 | 2022-05-19 | Hoffmann-La Roche Inc. | Nucleic acid constructs for simultaneous gene activation |
| CN114317608B (zh) * | 2020-12-28 | 2023-08-22 | 陕西杆粒生物科技有限公司 | 一种基因敲除型杆状病毒表达载体 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0127839B1 (en) | 1983-05-27 | 1992-07-15 | THE TEXAS A&M UNIVERSITY SYSTEM | Method for producing a recombinant baculovirus expression vector |
| US4745051A (en) | 1983-05-27 | 1988-05-17 | The Texas A&M University System | Method for producing a recombinant baculovirus expression vector |
| DK518384A (da) | 1984-01-31 | 1985-07-01 | Idaho Res Found | Vektor til fremstilling af et gen-produkt i insektceller, fremgangsmaade til dens fremstilling samt dens anvendelse |
| FR2664905B1 (fr) * | 1990-07-18 | 1994-08-12 | Agronomique Inst Nat Rech | Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus. |
| CN1205741A (zh) * | 1995-12-22 | 1999-01-20 | 纳幕尔杜邦公司 | 重组杆状病毒的生产 |
-
2012
- 2012-07-27 IN IN688CHN2014 patent/IN2014CN00688A/en unknown
- 2012-07-27 US US14/234,949 patent/US10480010B2/en not_active Expired - Fee Related
- 2012-07-27 ES ES12745446.0T patent/ES2623780T3/es active Active
- 2012-07-27 BR BR112014001863A patent/BR112014001863A2/pt active Search and Examination
- 2012-07-27 JP JP2014522116A patent/JP6122430B2/ja active Active
- 2012-07-27 DK DK12745446.0T patent/DK2737071T3/en active
- 2012-07-27 EP EP12745446.0A patent/EP2737071B1/en not_active Not-in-force
- 2012-07-27 CA CA2842392A patent/CA2842392C/en not_active Expired - Fee Related
- 2012-07-27 CN CN201280037489.9A patent/CN103748229A/zh active Pending
- 2012-07-27 WO PCT/EP2012/064843 patent/WO2013014294A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| US10480010B2 (en) | 2019-11-19 |
| IN2014CN00688A (enEXAMPLES) | 2015-04-03 |
| JP6122430B2 (ja) | 2017-04-26 |
| WO2013014294A2 (en) | 2013-01-31 |
| BR112014001863A2 (pt) | 2017-02-21 |
| DK2737071T3 (en) | 2017-05-08 |
| EP2737071A2 (en) | 2014-06-04 |
| US20140356904A1 (en) | 2014-12-04 |
| JP2014522658A (ja) | 2014-09-08 |
| WO2013014294A3 (en) | 2013-04-04 |
| EP2737071B1 (en) | 2017-03-15 |
| CA2842392A1 (en) | 2013-01-31 |
| ES2623780T3 (es) | 2017-07-12 |
| CN103748229A (zh) | 2014-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20170718 |
|
| MKLA | Lapsed |
Effective date: 20220727 |