CA2842034C - Protection of cells from alu-rna-induced degeneration and inhibitors for protecting cells - Google Patents
Protection of cells from alu-rna-induced degeneration and inhibitors for protecting cells Download PDFInfo
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- CA2842034C CA2842034C CA2842034A CA2842034A CA2842034C CA 2842034 C CA2842034 C CA 2842034C CA 2842034 A CA2842034 A CA 2842034A CA 2842034 A CA2842034 A CA 2842034A CA 2842034 C CA2842034 C CA 2842034C
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| US9441223B2 (en) | 2012-09-05 | 2016-09-13 | Cold Spring Harbor Laboratory, LLC | Transposable elements, TDP-43, and neurodegenerative disorders |
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| WO2016022914A1 (en) * | 2014-08-08 | 2016-02-11 | Moderna Therapeutics, Inc. | Compositions and methods for the treatment of ophthalmic diseases and conditions |
| US11219623B2 (en) | 2015-02-26 | 2022-01-11 | University Of Kentucky Research Foundation | Inflammasome inhibition for the treatment of Parkinson's disease, Alzheimer's disease and multiple sclerosis |
| PT4215527T (pt) | 2015-02-26 | 2025-01-07 | Univ Kentucky Res Found | Composições e métodos para tratar a degradação retinal |
| CN108350046B (zh) | 2015-09-03 | 2022-04-01 | 在本-古里安大学的B．G．内盖夫科技与应用有限公司 | Vdac1衍生肽的类似物 |
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| EP3377630A4 (en) | 2015-11-16 | 2020-01-01 | Olix Pharmaceuticals, Inc. | Treatment of age-related macular degeneration using rna complexes that target myd88 or tlr3 |
| CN108779463B (zh) | 2016-02-02 | 2022-05-24 | 奥利克斯医药有限公司 | 使用靶向IL4Rα、TRPA1或F2RL1的RNA复合物治疗特应性皮炎和哮喘 |
| EP3464325A1 (en) * | 2016-06-07 | 2019-04-10 | Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. | Backbone cyclized inhibitory peptides of myeloid differentiation factor 88 (myd88) |
| WO2017214553A1 (en) * | 2016-06-09 | 2017-12-14 | The General Hospital Corporation | Modulating the cellular stress response |
| KR101916652B1 (ko) | 2016-06-29 | 2018-11-08 | 올릭스 주식회사 | 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도 |
| US20190185820A1 (en) * | 2016-08-26 | 2019-06-20 | The Regents Of The University Of California | Compositions and Methods for Inhibiting Stem Cell Aging |
| DK3558335T3 (da) | 2016-12-23 | 2023-07-24 | Casp Aid Inc | Caspase-1 inhibition and uses thereof for prevention and treatment of neurological conditions |
| US11591600B2 (en) | 2017-02-10 | 2023-02-28 | OliX Pharmaceuticals. Inc. | Long double-stranded RNA for RNA interference |
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| EP3607063A4 (en) * | 2017-04-03 | 2021-01-13 | Duke University | COMPOSITIONS AND METHODS FOR DIFFERENTIAL INDUCTION OF CELLULAR DEATH AND INTERFERON EXPRESSION |
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| BR112020025018A2 (pt) * | 2018-06-27 | 2021-03-23 | Children's Medical Center Corporation | compostos para inibição de inflamação |
| KR102138256B1 (ko) * | 2018-09-13 | 2020-08-13 | 한국과학기술연구원 | 케스페이즈-1 활성 측정용 프로브, 이를 포함하는 염증성 질환 진단용 조성물 |
| US20210348164A1 (en) * | 2018-10-09 | 2021-11-11 | University Of Virginia Patent Foundation | Endogenous cytoplasmic alu complementary dna in age-related macular degeneration |
| CN110305957B (zh) * | 2019-08-22 | 2022-07-29 | 中国水产科学研究院淡水渔业研究中心 | 一种鉴定黄颡鱼脂肪肝程度的试剂盒及其鉴定方法 |
| WO2021041317A1 (en) * | 2019-08-23 | 2021-03-04 | University Of Virginia Patent Foundation | Ddx17 and nlrc4 targeting for inflammatory diseases |
| CN115484986A (zh) * | 2020-01-06 | 2022-12-16 | 海阳制药 | 用于预防或治疗黄斑变性的含有细胞可渗透的核酸复合物作为活性成分的组合物 |
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| CN111358950A (zh) * | 2020-03-20 | 2020-07-03 | 厦门大学 | Caspase-1及ASC/Caspase-8作为靶点的应用 |
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| CN115969844B (zh) * | 2021-12-28 | 2024-04-02 | 首都医科大学附属北京同仁医院 | Nox2特异性抑制剂在制备视网膜变性药物中的应用 |
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| EP3366302A1 (en) | 2018-08-29 |
| CN103889461B (zh) | 2016-11-09 |
| CA2842034A1 (en) | 2013-01-24 |
| EP2734240A2 (en) | 2014-05-28 |
| AU2012284223B2 (en) | 2017-06-22 |
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