CA2840924A1 - Use of salmonella flagellin derivative in preparation of drug for preventing and treating inflammatory bowel diseases - Google Patents

Use of salmonella flagellin derivative in preparation of drug for preventing and treating inflammatory bowel diseases Download PDF

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Publication number
CA2840924A1
CA2840924A1 CA2840924A CA2840924A CA2840924A1 CA 2840924 A1 CA2840924 A1 CA 2840924A1 CA 2840924 A CA2840924 A CA 2840924A CA 2840924 A CA2840924 A CA 2840924A CA 2840924 A1 CA2840924 A1 CA 2840924A1
Authority
CA
Canada
Prior art keywords
czlc331
protein
tat
drug
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2840924A
Other languages
English (en)
French (fr)
Inventor
Chenggang Zhang
Junhuai LI
Yang Xu
Yonghong Wu
Weiguang Li
Yanchun ZHANG
Yan Gao
Zhihui Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Sciscape Biomedicine Science & Technology Co Ltd
Institute of Radiation Medicine of CAMMS
Original Assignee
Suzhou Sciscape Biomedicine Science & Technology Co Ltd
Institute of Radiation Medicine of CAMMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Sciscape Biomedicine Science & Technology Co Ltd, Institute of Radiation Medicine of CAMMS filed Critical Suzhou Sciscape Biomedicine Science & Technology Co Ltd
Publication of CA2840924A1 publication Critical patent/CA2840924A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/255Salmonella (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893Tablet coating processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2840924A 2011-07-05 2012-01-19 Use of salmonella flagellin derivative in preparation of drug for preventing and treating inflammatory bowel diseases Abandoned CA2840924A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201110186065 2011-07-05
CN201110186065.6 2011-07-05
PCT/CN2012/000097 WO2013004069A1 (zh) 2011-07-05 2012-01-19 沙门氏菌鞭毛蛋白衍生物在制备防治炎症性肠病药物中的应用

Publications (1)

Publication Number Publication Date
CA2840924A1 true CA2840924A1 (en) 2013-01-10

Family

ID=47436474

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2840924A Abandoned CA2840924A1 (en) 2011-07-05 2012-01-19 Use of salmonella flagellin derivative in preparation of drug for preventing and treating inflammatory bowel diseases

Country Status (8)

Country Link
US (2) US9259453B2 (https=)
EP (1) EP2730287B1 (https=)
JP (1) JP5876930B2 (https=)
KR (1) KR101814558B1 (https=)
CN (1) CN102861317B (https=)
AU (1) AU2012278744B2 (https=)
CA (1) CA2840924A1 (https=)
WO (1) WO2013004069A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11273198B2 (en) 2017-05-04 2022-03-15 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US10402165B2 (en) 2017-08-30 2019-09-03 Gsi Technology Inc. Concurrent multi-bit adder
CN108159397A (zh) * 2018-02-28 2018-06-15 中南大学湘雅三医院 一种肠罗斯氏菌重组鞭毛蛋白在制备防治炎症性肠病药物中的应用
CN108404113A (zh) * 2018-05-16 2018-08-17 中国人民解放军军事科学院军事医学研究院 用于抗辐射损伤的口服辐抗肽药物组合物
US20220218786A1 (en) * 2019-03-28 2022-07-14 The Catholic University Of Korea Industry-Academic Cooperation Foundation Composition for preventing or treating graft-versus-host disease comprising tlr5 agonist derived from flagellin as effective component
CN110420317B (zh) * 2019-07-25 2022-11-22 中国人民解放军军事科学院军事医学研究院 Cblb502蛋白在防治创伤后应激障碍中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050073865A (ko) * 2004-01-12 2005-07-18 대한민국(전남대학교총장) 비브리오 패혈증균 편모 구성인자 플라젤린을유효성분으로 함유하는 백신 보조제
EP2460534A1 (en) * 2004-12-22 2012-06-06 Cleveland Clinic Foundation Flagellin related polypeptides and uses thereof
EP2374474A1 (en) * 2005-01-19 2011-10-12 Vaxinnate Corporation Compositions comprising pathogen-associated molecular patterns and antigens and their use to stimulate an immune response
CA2531261A1 (en) * 2005-12-21 2007-06-21 Institut Pasteur Control of intestinal inflammatory syndromes with a preparation of killed or non infectious bacteria
BRPI0911604A2 (pt) * 2008-04-25 2015-12-15 Inst Systems Biology vacinas de polipeptídeo de flagelina
CN101411872A (zh) 2008-11-25 2009-04-22 中国科学院武汉病毒研究所 预防龋齿的疫苗试剂盒及其使用方法

Also Published As

Publication number Publication date
US9259453B2 (en) 2016-02-16
EP2730287B1 (en) 2018-02-28
WO2013004069A1 (zh) 2013-01-10
US20140248348A1 (en) 2014-09-04
JP5876930B2 (ja) 2016-03-02
CN102861317B (zh) 2014-07-02
KR101814558B1 (ko) 2018-01-30
AU2012278744B2 (en) 2016-11-24
EP2730287A4 (en) 2015-03-18
EP2730287A1 (en) 2014-05-14
US20160060305A1 (en) 2016-03-03
KR20140054018A (ko) 2014-05-08
US9630999B2 (en) 2017-04-25
AU2012278744A1 (en) 2014-02-20
NZ619871A (en) 2016-02-26
JP2014522819A (ja) 2014-09-08
CN102861317A (zh) 2013-01-09

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20160908

FZDE Discontinued

Effective date: 20200831