CA2838784A1 - Pyrazolo[3,4-c]pyridine compounds and methods of use - Google Patents
Pyrazolo[3,4-c]pyridine compounds and methods of use Download PDFInfo
- Publication number
- CA2838784A1 CA2838784A1 CA2838784A CA2838784A CA2838784A1 CA 2838784 A1 CA2838784 A1 CA 2838784A1 CA 2838784 A CA2838784 A CA 2838784A CA 2838784 A CA2838784 A CA 2838784A CA 2838784 A1 CA2838784 A1 CA 2838784A1
- Authority
- CA
- Canada
- Prior art keywords
- pyridin
- pyrazolo
- pyridine
- compound
- pyrazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 150000005231 pyrazolo[3,4-c]pyridines Chemical class 0.000 title abstract description 7
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- 108060006633 protein kinase Proteins 0.000 claims abstract description 5
- -1 (piperidin-4-yl)ethyl Chemical group 0.000 claims description 170
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 38
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- 125000000582 cycloheptyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims description 9
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims description 9
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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| PCT/EP2012/065643 WO2013024002A1 (en) | 2011-08-12 | 2012-08-10 | PYRAZOLO[3,4-c]PYRIDINE COMPOUNDS AND METHODS OF USE |
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| US5543523A (en) | 1994-11-15 | 1996-08-06 | Regents Of The University Of Minnesota | Method and intermediates for the synthesis of korupensamines |
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- 2012-08-10 US US13/571,595 patent/US9260425B2/en not_active Expired - Fee Related
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| RU2638116C2 (ru) | 2017-12-15 |
| MX355852B (es) | 2018-05-02 |
| JP6133291B2 (ja) | 2017-05-24 |
| US20130039906A1 (en) | 2013-02-14 |
| EP2742046A1 (en) | 2014-06-18 |
| US20160159797A1 (en) | 2016-06-09 |
| MX2014001239A (es) | 2014-03-21 |
| BR112014003296A2 (pt) | 2017-03-14 |
| CN103874700B (zh) | 2018-03-30 |
| US9850239B2 (en) | 2017-12-26 |
| JP2014521711A (ja) | 2014-08-28 |
| US9260425B2 (en) | 2016-02-16 |
| RU2014106966A (ru) | 2015-09-20 |
| KR20140071361A (ko) | 2014-06-11 |
| WO2013024002A1 (en) | 2013-02-21 |
| CN103874700A (zh) | 2014-06-18 |
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