CA2836898A1 - Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof - Google Patents
Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof Download PDFInfo
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- CA2836898A1 CA2836898A1 CA2836898A CA2836898A CA2836898A1 CA 2836898 A1 CA2836898 A1 CA 2836898A1 CA 2836898 A CA2836898 A CA 2836898A CA 2836898 A CA2836898 A CA 2836898A CA 2836898 A1 CA2836898 A1 CA 2836898A1
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| PCT/US2012/028926 WO2012161856A1 (en) | 2011-05-20 | 2012-03-13 | Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof |
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| CA2836898A1 true CA2836898A1 (en) | 2012-11-29 |
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| CA2621083C (en) | 2005-08-30 | 2017-04-11 | University Of Miami | Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins |
| US9896511B2 (en) | 2007-01-10 | 2018-02-20 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Antibodies that bind to TL1A and methods of treating inflammatory or autoimmune disease comprising administering such antibodies |
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| SG178125A1 (en) | 2009-08-03 | 2012-03-29 | Univ Miami | Method for in vivo expansion of t regulatory cells |
| US8766034B2 (en) | 2010-09-22 | 2014-07-01 | Cedars-Sinai Medical Center | TL1A model of inflammation fibrosis and autoimmunity |
| JP2014531210A (ja) | 2011-09-30 | 2014-11-27 | テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド | ＴＬ１ａに対する抗体およびその使用 |
| JP2016503818A (ja) * | 2013-01-02 | 2016-02-08 | グレンマーク ファーマシューティカルズ， エセ．アー． | Ｔｌ１ａと結合する抗体およびその使用 |
| WO2014110258A1 (en) | 2013-01-09 | 2014-07-17 | Podack Eckhard R | Compositions and methods for the regulation of t regulatory cells using tl1a-ig fusion protein |
| WO2014160883A1 (en) | 2013-03-27 | 2014-10-02 | Cedars-Sinai Medical Center | Treating fibrosis and inflammation by inhibiting tl1a |
| US20160096885A1 (en) * | 2013-05-17 | 2016-04-07 | Cedars-Sinal Medical Center | Distinct effects of ifn-gamma and il-17 on tl1a modulated inflammation and fibrosis |
| EP3498867B1 (en) * | 2013-05-17 | 2021-09-29 | Cedars-Sinai Medical Center | Variants of tnfsf15 and dcr3 associated with crohn's disease |
| US10316083B2 (en) | 2013-07-19 | 2019-06-11 | Cedars-Sinai Medical Center | Signature of TL1A (TNFSF15) signaling pathway |
| AU2014317991A1 (en) * | 2013-09-06 | 2016-03-10 | Cedars-Sinai Medical Center | Systems, devices and methods for anti-TL1A therapy |
| SG11201602671WA (en) * | 2013-11-13 | 2016-05-30 | Pfizer | Tumor necrosis factor-like ligand 1a specific antibodies and compositions and uses thereof |
| CA2947255A1 (en) * | 2014-04-28 | 2015-11-05 | The National Institute for Biotechnology in the Negev Ltd. | Variants of dr3 and use thereof |
| EP3337465B1 (en) | 2015-08-21 | 2021-11-24 | The Children's Hospital of Philadelphia | Compositions and methods for use in combination for the treatment and diagnosis of autoimmune diseases |
| TWI703158B (zh) | 2015-09-18 | 2020-09-01 | 美商希佛隆公司 | 特異性結合tl1a之抗體 |
| US20180319889A1 (en) * | 2015-11-02 | 2018-11-08 | La Jolla Institute For Allergy & Immunology | Method and medicament for treating airway and/or lung diseases |
| CR20180365A (es) | 2015-12-16 | 2018-09-28 | Amgen Inc | PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS |
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-
2012
- 2012-03-13 WO PCT/US2012/028926 patent/WO2012161856A1/en not_active Ceased
- 2012-03-13 CA CA2836898A patent/CA2836898A1/en not_active Abandoned
- 2012-03-13 JP JP2014512833A patent/JP2014518883A/ja not_active Withdrawn
- 2012-03-13 MX MX2013013329A patent/MX2013013329A/es not_active Application Discontinuation
- 2012-03-13 AU AU2012259312A patent/AU2012259312A1/en not_active Abandoned
- 2012-03-13 US US13/419,203 patent/US9068003B2/en active Active
- 2012-03-13 EP EP12790157.7A patent/EP2709664A4/en not_active Withdrawn
- 2012-03-13 KR KR1020137033718A patent/KR20140104344A/ko not_active Withdrawn
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|---|---|
| EP2709664A1 (en) | 2014-03-26 |
| AU2012259312A8 (en) | 2014-02-27 |
| KR20140104344A (ko) | 2014-08-28 |
| WO2012161856A1 (en) | 2012-11-29 |
| US20120263718A1 (en) | 2012-10-18 |
| MX2013013329A (es) | 2014-04-16 |
| EP2709664A4 (en) | 2015-06-10 |
| US9068003B2 (en) | 2015-06-30 |
| JP2014518883A (ja) | 2014-08-07 |
| AU2012259312A1 (en) | 2013-12-12 |
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