CA2836599A1 - Process for purifying heparan-n-sulfatase - Google Patents
Process for purifying heparan-n-sulfatase Download PDFInfo
- Publication number
- CA2836599A1 CA2836599A1 CA2836599A CA2836599A CA2836599A1 CA 2836599 A1 CA2836599 A1 CA 2836599A1 CA 2836599 A CA2836599 A CA 2836599A CA 2836599 A CA2836599 A CA 2836599A CA 2836599 A1 CA2836599 A1 CA 2836599A1
- Authority
- CA
- Canada
- Prior art keywords
- hns
- process according
- heparan
- sulfatase
- column
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108010089932 heparan sulfate sulfatase Proteins 0.000 title claims abstract description 232
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161488090P | 2011-05-19 | 2011-05-19 | |
| US61/488,090 | 2011-05-19 | ||
| PCT/US2012/038630 WO2012159053A1 (en) | 2011-05-19 | 2012-05-18 | Process for purifying heparan-n-sulfatase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2836599A1 true CA2836599A1 (en) | 2012-11-22 |
Family
ID=47177365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2836599A Abandoned CA2836599A1 (en) | 2011-05-19 | 2012-05-18 | Process for purifying heparan-n-sulfatase |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120329133A1 (enExample) |
| EP (2) | EP2929892B1 (enExample) |
| JP (2) | JP2014517692A (enExample) |
| AR (1) | AR086445A1 (enExample) |
| CA (1) | CA2836599A1 (enExample) |
| HK (1) | HK1214960A1 (enExample) |
| TW (1) | TW201307563A (enExample) |
| WO (1) | WO2012159053A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11584777B2 (en) | 2017-08-31 | 2023-02-21 | Green Cross Corporation | Method for purifying a sulfatase protein |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1460131A3 (en) * | 2000-03-22 | 2005-06-01 | Octagene GmbH | Production of recombinant blood clotting factors in human cell lines |
| JP4319979B2 (ja) * | 2002-04-26 | 2009-08-26 | ジェネンテック・インコーポレーテッド | タンパク質の非アフィニティ精製 |
| US7118901B2 (en) * | 2002-12-18 | 2006-10-10 | Roche Diagnostics Operations, Inc. | Recombinant bovine pancreatic desoxyribonuclease I with high specific activity |
| WO2005077093A2 (en) * | 2004-02-06 | 2005-08-25 | Biomarin Pharmaceutical Inc. | Manufacture of highly phosphorylated lysosomal enzymes and uses thereof |
| CA2592261C (en) * | 2004-12-10 | 2015-11-24 | Zymogenetics Inc. | Fgf18 production in prokaryotic hosts |
| EP2141178A4 (en) * | 2007-04-02 | 2010-05-19 | Kyowa Hakko Kirin Co Ltd | PROCESS FOR PRODUCING ANTITHROMBIN COMPOSITION |
| KR101744142B1 (ko) * | 2008-01-18 | 2017-06-07 | 바이오마린 파머수티컬 인크. | 활성이고 높은 정도로 인산화된 인간 리소좀 술파타아제 효소의 제조 및 그 용도 |
| MX2013000320A (es) * | 2010-06-25 | 2013-06-05 | Shire Human Genetic Therapies | Composiciones y metodos para suministro al sistema nervioso central de heparan n-sulfatasa. |
-
2012
- 2012-05-17 TW TW101117561A patent/TW201307563A/zh unknown
- 2012-05-18 WO PCT/US2012/038630 patent/WO2012159053A1/en not_active Ceased
- 2012-05-18 US US13/475,568 patent/US20120329133A1/en not_active Abandoned
- 2012-05-18 EP EP15166651.8A patent/EP2929892B1/en active Active
- 2012-05-18 CA CA2836599A patent/CA2836599A1/en not_active Abandoned
- 2012-05-18 JP JP2014511591A patent/JP2014517692A/ja not_active Ceased
- 2012-05-18 EP EP12785579.9A patent/EP2709654A4/en not_active Withdrawn
- 2012-05-18 AR ARP120101760A patent/AR086445A1/es unknown
-
2016
- 2016-03-15 HK HK16102969.5A patent/HK1214960A1/en unknown
- 2016-11-01 JP JP2016214041A patent/JP2017029170A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2929892B1 (en) | 2018-07-04 |
| EP2709654A1 (en) | 2014-03-26 |
| HK1214960A1 (en) | 2016-08-12 |
| EP2709654A4 (en) | 2014-11-12 |
| WO2012159053A1 (en) | 2012-11-22 |
| US20120329133A1 (en) | 2012-12-27 |
| TW201307563A (zh) | 2013-02-16 |
| JP2017029170A (ja) | 2017-02-09 |
| JP2014517692A (ja) | 2014-07-24 |
| EP2929892A1 (en) | 2015-10-14 |
| AR086445A1 (es) | 2013-12-11 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20180518 |