CA2836315A1 - Method for treating brain cancer - Google Patents
Method for treating brain cancer Download PDFInfo
- Publication number
- CA2836315A1 CA2836315A1 CA2836315A CA2836315A CA2836315A1 CA 2836315 A1 CA2836315 A1 CA 2836315A1 CA 2836315 A CA2836315 A CA 2836315A CA 2836315 A CA2836315 A CA 2836315A CA 2836315 A1 CA2836315 A1 CA 2836315A1
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- Prior art keywords
- drr
- cells
- expression
- antisense
- glioma
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34575110P | 2010-05-18 | 2010-05-18 | |
| US61/345,751 | 2010-05-18 | ||
| PCT/CA2011/000591 WO2011143762A1 (en) | 2010-05-18 | 2011-05-18 | Method for reducing expression of downregulated iν renal cell carcinoma iν malignant gliomas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2836315A1 true CA2836315A1 (en) | 2011-11-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2836315A Abandoned CA2836315A1 (en) | 2010-05-18 | 2011-05-18 | Method for treating brain cancer |
Country Status (7)
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| WO2013075233A1 (en) * | 2011-11-21 | 2013-05-30 | The Royal Institution For The Advancement Of Learning / Mcgill University | Method for treating brain cancer |
| RU2747822C2 (ru) * | 2016-03-14 | 2021-05-14 | Ф. Хоффманн-Ля Рош Аг | Олигонуклеотиды для понижения экспрессии pd-l1 |
| WO2019154884A1 (en) * | 2018-02-07 | 2019-08-15 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for determining cancer invasiveness and patient prognosis |
| US12104152B2 (en) | 2018-03-19 | 2024-10-01 | The Trustees Of The University Of Pennsylvania | 2′F-ANA-LET7 mediated utrophin upregulation for DMD therapy |
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| SE9704836D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Pharma Inc | Novel receptor |
| US20070048738A1 (en) * | 2003-07-14 | 2007-03-01 | Mayo Foundation For Medical Education And Research | Methods and compositions for diagnosis, staging and prognosis of prostate cancer |
| US20050244851A1 (en) * | 2004-01-13 | 2005-11-03 | Affymetrix, Inc. | Methods of analysis of alternative splicing in human |
| EP1737957A1 (en) * | 2004-04-22 | 2007-01-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | UNIVERSAL TARGET SEQUENCES FOR siRNA GENE SILENCING |
| EP1815021A2 (en) * | 2004-11-03 | 2007-08-08 | Almac Diagnostics Limited | Transcriptome microarray technology and methods of using the same |
| CN101474413A (zh) * | 2009-02-10 | 2009-07-08 | 四川大学 | Drr1基因在制备抗肿瘤药物中的用途 |
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| US9493772B2 (en) | 2016-11-15 |
| JP2013534410A (ja) | 2013-09-05 |
| US20130197057A1 (en) | 2013-08-01 |
| EP2571989A1 (en) | 2013-03-27 |
| CN103370414A (zh) | 2013-10-23 |
| WO2011143762A1 (en) | 2011-11-24 |
| US20140343124A1 (en) | 2014-11-20 |
| EP2571989A4 (en) | 2014-08-13 |
| AU2011256098A1 (en) | 2013-01-10 |
| US8765708B2 (en) | 2014-07-01 |
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