CA2826683A1 - Hsa-related compositions and methods of use - Google Patents
Hsa-related compositions and methods of use Download PDFInfo
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- CA2826683A1 CA2826683A1 CA2826683A CA2826683A CA2826683A1 CA 2826683 A1 CA2826683 A1 CA 2826683A1 CA 2826683 A CA2826683 A CA 2826683A CA 2826683 A CA2826683 A CA 2826683A CA 2826683 A1 CA2826683 A1 CA 2826683A1
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- residue
- hsa
- amino acid
- polypeptide
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| USPCT/US2011/024855 | 2011-02-15 | ||
| PCT/US2011/024855 WO2011103076A1 (en) | 2010-02-16 | 2011-02-15 | Hsa-related compositions and methods of use |
| PCT/US2011/047040 WO2012112188A1 (en) | 2011-02-15 | 2011-08-09 | Hsa-related compositions and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2826683A1 true CA2826683A1 (en) | 2012-08-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2826683A Abandoned CA2826683A1 (en) | 2011-02-15 | 2011-08-09 | Hsa-related compositions and methods of use |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP2675471A4 (enExample) |
| JP (1) | JP2014510518A (enExample) |
| KR (1) | KR20140012094A (enExample) |
| CN (1) | CN103379915A (enExample) |
| AU (1) | AU2011359378A1 (enExample) |
| CA (1) | CA2826683A1 (enExample) |
| WO (1) | WO2012112188A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR101722961B1 (ko) | 2009-02-11 | 2017-04-04 | 알부메딕스 에이/에스 | 알부민 변이체 및 접합체 |
| MX2012004793A (es) | 2009-10-30 | 2012-07-20 | Novozymes Biopharma Dk As | Variantes de albumina. |
| AU2011218294A1 (en) | 2010-02-16 | 2012-08-30 | Medimmune, Llc | HSA-related compositions and methods of use |
| JP5969458B2 (ja) | 2010-04-09 | 2016-08-17 | アルブミディクス アクティーゼルスカブ | アルブミン誘導体及び変異体 |
| US9045564B2 (en) | 2011-02-15 | 2015-06-02 | Medimmune, Llc | HSA-related compositions and methods of use |
| CA2838246C (en) | 2011-06-13 | 2018-07-10 | Csl Limited | Antibodies against g-csfr and uses thereof |
| US20140315817A1 (en) | 2011-11-18 | 2014-10-23 | Eleven Biotherapeutics, Inc. | Variant serum albumin with improved half-life and other properties |
| DK2825556T3 (en) | 2012-03-16 | 2018-04-16 | Albumedix As | albumin Variants |
| KR20150082422A (ko) * | 2012-11-08 | 2015-07-15 | 노보자임스 바이오파마 디케이 에이/에스 | 알부민 변이체 |
| CN105007722A (zh) | 2013-02-16 | 2015-10-28 | 诺维信生物制药丹麦公司 | 药代动力学动物模型 |
| CA2902657C (en) * | 2013-03-15 | 2022-05-10 | Affibody Ab | Fcrn binding polypeptides |
| EP3007717B1 (en) | 2013-06-12 | 2018-08-29 | Pharis Biotec GmbH | Peptides with antagonistic activities against natural cxcr4 |
| EP3044232A1 (en) * | 2013-09-13 | 2016-07-20 | Novozymes Biopharma DK A/S | Albumin variants |
| CN105992770B (zh) * | 2013-11-01 | 2021-06-25 | 奥斯陆大学 | 白蛋白的变体及其用途 |
| CA2977675A1 (en) | 2015-03-12 | 2016-09-15 | Medimmune, Llc | Method of purifying albumin-fusion proteins |
| EP3337816B1 (en) | 2015-08-20 | 2024-02-14 | Albumedix Ltd | Albumin variants and conjugates |
| EP3708580B1 (en) * | 2015-09-23 | 2023-11-01 | Bristol-Myers Squibb Company | Fast-off rate serum albumin binding fibronectin type iii domains |
| CA3005953A1 (en) | 2015-12-22 | 2017-06-29 | Albumedix Ltd | Improved protein expression strains |
| JP7146637B2 (ja) | 2015-12-22 | 2022-10-04 | アルブミディクス リミティド | 改善されたタンパク質発現株 |
| JP2020500306A (ja) | 2016-11-04 | 2020-01-09 | オーフス ウニベルシテット | 新生児Ｆｃ受容体の過剰発現により特徴づけられる腫瘍の同定と治療 |
| US11130979B2 (en) | 2017-06-20 | 2021-09-28 | Albumedix Ltd | Protein expression strains |
| PL3717011T3 (pl) | 2017-11-29 | 2023-03-27 | Csl Limited | Sposób leczenia lub zapobiegania uszkodzeniu niedokrwienno- reperfuzyjnemu |
| WO2019178645A1 (en) | 2018-03-23 | 2019-09-26 | Csl Limited | Method of treating asthma |
| PT3793586T (pt) | 2018-05-16 | 2024-07-10 | Csl Ltd | Variantes do receptor solúvel do complemento de tipo 1 e sua utilização |
| EA202191179A1 (ru) | 2018-10-29 | 2021-09-09 | Байоджен Ма Инк. | Гуманизированные и стабилизированные варианты fc5 для улучшения транспорта через гематоэнцефалический барьер |
| AU2020343512A1 (en) | 2019-09-06 | 2022-04-07 | Novartis Ag | Therapeutic fusion proteins |
| WO2021111143A1 (en) | 2019-12-04 | 2021-06-10 | Albumedix Limited | Methods and compositions produced thereby |
| CN114478800B (zh) * | 2021-02-05 | 2022-10-11 | 华南理工大学 | 基于血清白蛋白的融合蛋白、纳米组装体及其制备方法和应用 |
| CN113912730B (zh) * | 2021-12-14 | 2022-03-04 | 北京科诺信诚科技有限公司 | 缓释的抗FcRn抗体或抗原结合片段及其应用 |
| WO2024089258A1 (en) | 2022-10-28 | 2024-05-02 | Aarhus Universitet | Albumin conjugated to cpg oligodeoxynucleotides as super-boosters of immune response |
| EP4442251A1 (en) | 2023-04-05 | 2024-10-09 | Albumedix Ltd | Formulations and uses thereof |
| WO2025007195A1 (en) | 2023-07-05 | 2025-01-09 | CSL Innovation Pty Ltd | Methods of treating or preventing a complication of sickle cell disease |
| WO2025158071A1 (en) | 2024-01-26 | 2025-07-31 | Sartorius Albumedix Limited | Retroviral preparations containing albumin for enhancing transduction efficiency, uses thereof for cell transduction |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9404270D0 (en) * | 1994-03-05 | 1994-04-20 | Delta Biotechnology Ltd | Yeast strains and modified albumins |
| US20080194481A1 (en) * | 2001-12-21 | 2008-08-14 | Human Genome Sciences, Inc. | Albumin Fusion Proteins |
| US20060051859A1 (en) * | 2004-09-09 | 2006-03-09 | Yan Fu | Long acting human interferon analogs |
| MX2010011145A (es) * | 2008-04-11 | 2011-04-11 | Merrimack Pharmaceuticals Inc | Enlazadores de la albumina de suero humana y conjugados de la misma. |
| WO2010118169A2 (en) * | 2009-04-08 | 2010-10-14 | The Regents Of The University Of California | Human protein scaffold with controlled serum pharmacokinetics |
| AU2011218294A1 (en) * | 2010-02-16 | 2012-08-30 | Medimmune, Llc | HSA-related compositions and methods of use |
-
2011
- 2011-08-09 CN CN2011800674634A patent/CN103379915A/zh active Pending
- 2011-08-09 AU AU2011359378A patent/AU2011359378A1/en not_active Abandoned
- 2011-08-09 EP EP11858565.2A patent/EP2675471A4/en not_active Withdrawn
- 2011-08-09 JP JP2013553420A patent/JP2014510518A/ja active Pending
- 2011-08-09 KR KR1020137024189A patent/KR20140012094A/ko not_active Withdrawn
- 2011-08-09 WO PCT/US2011/047040 patent/WO2012112188A1/en not_active Ceased
- 2011-08-09 CA CA2826683A patent/CA2826683A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014510518A (ja) | 2014-05-01 |
| WO2012112188A1 (en) | 2012-08-23 |
| EP2675471A4 (en) | 2015-01-28 |
| KR20140012094A (ko) | 2014-01-29 |
| CN103379915A (zh) | 2013-10-30 |
| AU2011359378A1 (en) | 2013-10-03 |
| EP2675471A1 (en) | 2013-12-25 |
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Effective date: 20170809 |