CA2819102A1 - Kat ii inhibitors - Google Patents
Kat ii inhibitors Download PDFInfo
- Publication number
- CA2819102A1 CA2819102A1 CA2819102A CA2819102A CA2819102A1 CA 2819102 A1 CA2819102 A1 CA 2819102A1 CA 2819102 A CA2819102 A CA 2819102A CA 2819102 A CA2819102 A CA 2819102A CA 2819102 A1 CA2819102 A1 CA 2819102A1
- Authority
- CA
- Canada
- Prior art keywords
- alkyl
- aryl
- compound
- mmol
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- ABBLRYAESUTTSD-NSHDSACASA-N (5s)-5-amino-3-benzyl-7-hydroxy-1-methyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one Chemical compound O=C([C@@H](N)CC=12)N(O)C=1N(C)N=C2CC1=CC=CC=C1 ABBLRYAESUTTSD-NSHDSACASA-N 0.000 claims 1
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| CA2819102A1 true CA2819102A1 (en) | 2012-06-07 |
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| US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| KR102458990B1 (ko) * | 2014-04-23 | 2022-10-25 | 미쓰비시 타나베 파마 코퍼레이션 | 신규한 바이시클릭 또는 트리시클릭 헤테로시클릭 화합물 |
| WO2016164754A1 (en) | 2015-04-09 | 2016-10-13 | Eisai R&D Management Co., Ltd. | Fgfr4 inhibitors |
| WO2016164703A1 (en) | 2015-04-09 | 2016-10-13 | Eisai R & D Management Co., Ltd. | Fgfr4 inhibitors |
| JP6853782B2 (ja) * | 2015-10-22 | 2021-03-31 | 田辺三菱製薬株式会社 | 新規二環性複素環化合物 |
| BR112021025531A2 (pt) * | 2019-06-20 | 2022-03-03 | Memorial Sloan Kettering Cancer Center | Moduladores de pirazol-piridona farmacêuticamente ativos da nedilação de cullin mediada por dcn1/2 |
| CN115038443A (zh) | 2019-11-22 | 2022-09-09 | 因西特公司 | 包含alk2抑制剂和jak2抑制剂的组合疗法 |
| AU2021268345A1 (en) | 2020-05-05 | 2022-11-10 | Nuvalent, Inc. | Heteroaromatic macrocyclic ether chemotherapeutic agents |
| WO2021226208A2 (en) | 2020-05-05 | 2021-11-11 | Nuvalent, Inc. | Heteroaromatic macrocyclic ether chemotherapeutic agents |
| WO2022165382A1 (en) * | 2021-01-29 | 2022-08-04 | Neurawell Therapeutics | Phenylethylidenehydrazine combination therapies |
| KR20240087788A (ko) | 2021-10-01 | 2024-06-19 | 뉴베일런트, 아이엔씨. | 헤테로방향족 매크로사이클릭 에테르 화합물의 고체 형태, 약학 조성물 및 제조 |
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