CA2817519C - Bin1 expression as a marker of skeletal muscle mass and neurological conditions - Google Patents

Bin1 expression as a marker of skeletal muscle mass and neurological conditions Download PDF

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Publication number
CA2817519C
CA2817519C CA2817519A CA2817519A CA2817519C CA 2817519 C CA2817519 C CA 2817519C CA 2817519 A CA2817519 A CA 2817519A CA 2817519 A CA2817519 A CA 2817519A CA 2817519 C CA2817519 C CA 2817519C
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Prior art keywords
seq
bin1
antibody
human
skeletal muscle
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CA2817519A
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English (en)
French (fr)
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CA2817519A1 (en
Inventor
Darryl Steven Shaw
Neil Gavin Shaw
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SARCOTEIN DIAGNOSTICS LLC
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2817519A 2010-11-09 2011-11-07 Bin1 expression as a marker of skeletal muscle mass and neurological conditions Active CA2817519C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41168310P 2010-11-09 2010-11-09
US61/411,683 2010-11-09
PCT/US2011/059574 WO2012087437A2 (en) 2010-11-09 2011-11-07 Bin1 expression as a marker of skeletal muscle mass and neurological conditions

Publications (2)

Publication Number Publication Date
CA2817519A1 CA2817519A1 (en) 2012-06-28
CA2817519C true CA2817519C (en) 2020-01-14

Family

ID=46314702

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2817519A Active CA2817519C (en) 2010-11-09 2011-11-07 Bin1 expression as a marker of skeletal muscle mass and neurological conditions

Country Status (6)

Country Link
US (1) US9891232B2 (https=)
EP (1) EP2638403B1 (https=)
JP (1) JP5866126B2 (https=)
AU (2) AU2011345312A1 (https=)
CA (1) CA2817519C (https=)
WO (1) WO2012087437A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010124240A2 (en) 2009-04-24 2010-10-28 The Regents Of The University Of California Bin1 as a prognostic marker in cardiovascular disease
US8999659B2 (en) 2010-10-20 2015-04-07 The Regents Of The University Of California Body fluid BIN1 as a marker of cardiac health
US9846159B2 (en) 2011-09-30 2017-12-19 Sarcotein Diagnostics, Llc BIN1 expression as a marker of cancer
WO2016141088A1 (en) 2015-03-02 2016-09-09 Sarcotein Diagnostics, Llc 13+/17+ bin1 expression as a marker of cardiac disorders
JP6539511B2 (ja) * 2015-06-17 2019-07-03 花王株式会社 運動機能の判定用マーカー
JP6886241B2 (ja) * 2016-01-07 2021-06-16 味の素株式会社 骨格筋面積の評価方法
MY198194A (en) * 2016-05-02 2023-08-09 Prothena Biosciences Ltd Antibodies Recognizing Tau
US12054543B2 (en) 2018-07-25 2024-08-06 Accurus Biosciences, Inc. CLDN 18.2-specific monoclonal antibodies and methods of use thereof
CA3115077A1 (en) * 2018-10-09 2020-04-16 Ibex Biosciences, Llc Antibodies directed to filamin-a and therapeutic uses thereof
WO2022132859A1 (en) * 2020-12-15 2022-06-23 Arizona Board Of Regents On Behalf Of Arizona State University Antibodies specific for qsox1 and methods of using the same
CN112778414B (zh) * 2020-12-31 2022-04-15 中南大学湘雅二医院 cBIN1抗体及其应用
CN112794900B (zh) * 2020-12-31 2022-10-25 中南大学湘雅二医院 cBIN1抗体及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048702A (en) * 1995-05-05 2000-04-11 The Wistar Institute Of Anatomy And Biology Murine and human box-dependent myc-interacting protein (Bin1) and uses therefor
WO2001004354A2 (en) 1999-07-07 2001-01-18 Regeneron Pharmaceuticals, Inc. Use of ras inhibitors of inhibiting muscle atrophy
US6831063B1 (en) * 1999-08-31 2004-12-14 The Wistar Institute Of Anatomy And Biology Bridging Integrator-2(Bin2) nucleic acid molecules and proteins and uses therefor
US20090088482A1 (en) * 2003-10-14 2009-04-02 The Trustees Of Columbia University In The City New York Compositions and Methods For Treating Heart Failure
ES2367311T3 (es) * 2004-04-15 2011-11-02 University Of Florida Research Foundation, Inc. Productos de degradación proteolítica de map-2 como biomarcadores de diagnóstico para las lesiones neurales.
WO2006009629A2 (en) * 2004-06-10 2006-01-26 New York University Methods and agents for maintaining muscle mass and for preventing muscle atrophy and biomarkers for monitoring same
US20100086481A1 (en) 2006-07-11 2010-04-08 Baird Alison E Differential expression of molecules associated with intra-cerebral hemorrhage
WO2010124240A2 (en) 2009-04-24 2010-10-28 The Regents Of The University Of California Bin1 as a prognostic marker in cardiovascular disease
US8999659B2 (en) * 2010-10-20 2015-04-07 The Regents Of The University Of California Body fluid BIN1 as a marker of cardiac health

Also Published As

Publication number Publication date
CA2817519A1 (en) 2012-06-28
JP2014500960A (ja) 2014-01-16
US20130324432A1 (en) 2013-12-05
WO2012087437A2 (en) 2012-06-28
US9891232B2 (en) 2018-02-13
EP2638403A2 (en) 2013-09-18
EP2638403B1 (en) 2017-03-22
AU2017201661A1 (en) 2017-03-30
AU2017201661B2 (en) 2019-01-17
EP2638403A4 (en) 2014-05-07
WO2012087437A3 (en) 2012-08-16
AU2011345312A1 (en) 2013-06-20
JP5866126B2 (ja) 2016-02-17

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