JP5866126B2 - 骨格筋量および神経性状態のマーカーとしてのbin1発現 - Google Patents
骨格筋量および神経性状態のマーカーとしてのbin1発現 Download PDFInfo
- Publication number
- JP5866126B2 JP5866126B2 JP2013538809A JP2013538809A JP5866126B2 JP 5866126 B2 JP5866126 B2 JP 5866126B2 JP 2013538809 A JP2013538809 A JP 2013538809A JP 2013538809 A JP2013538809 A JP 2013538809A JP 5866126 B2 JP5866126 B2 JP 5866126B2
- Authority
- JP
- Japan
- Prior art keywords
- bin1
- subject
- level
- skeletal muscle
- muscle mass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41168310P | 2010-11-09 | 2010-11-09 | |
| US61/411,683 | 2010-11-09 | ||
| PCT/US2011/059574 WO2012087437A2 (en) | 2010-11-09 | 2011-11-07 | Bin1 expression as a marker of skeletal muscle mass and neurological conditions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014500960A JP2014500960A (ja) | 2014-01-16 |
| JP2014500960A5 JP2014500960A5 (https=) | 2014-12-25 |
| JP5866126B2 true JP5866126B2 (ja) | 2016-02-17 |
Family
ID=46314702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538809A Active JP5866126B2 (ja) | 2010-11-09 | 2011-11-07 | 骨格筋量および神経性状態のマーカーとしてのbin1発現 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9891232B2 (https=) |
| EP (1) | EP2638403B1 (https=) |
| JP (1) | JP5866126B2 (https=) |
| AU (2) | AU2011345312A1 (https=) |
| CA (1) | CA2817519C (https=) |
| WO (1) | WO2012087437A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120094300A1 (en) | 2009-04-24 | 2012-04-19 | Robin Shaw | Bin1 as a Prognostic Marker in Cardiovascular Disease |
| JP5890840B2 (ja) * | 2010-10-20 | 2016-03-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 心臓健康状態のマーカーとしての体液bin1 |
| US9846159B2 (en) | 2011-09-30 | 2017-12-19 | Sarcotein Diagnostics, Llc | BIN1 expression as a marker of cancer |
| JP6742330B2 (ja) | 2015-03-02 | 2020-08-19 | サーコーティン ダイアグノスティックス エルエルシー | 心臓障害のマーカーとしての13+/17+bin1発現 |
| JP6539511B2 (ja) * | 2015-06-17 | 2019-07-03 | 花王株式会社 | 運動機能の判定用マーカー |
| JP6886241B2 (ja) * | 2016-01-07 | 2021-06-16 | 味の素株式会社 | 骨格筋面積の評価方法 |
| CA3022515A1 (en) * | 2016-05-02 | 2017-11-09 | Prothena Biosciences Limited | Antibodies recognizing tau |
| CN112770723B (zh) * | 2018-07-25 | 2024-08-02 | 阿克罗斯生物科学公司 | Cldn 18.2特异性单克隆抗体及其使用方法 |
| CA3115077A1 (en) * | 2018-10-09 | 2020-04-16 | Ibex Biosciences, Llc | Antibodies directed to filamin-a and therapeutic uses thereof |
| US20240026034A1 (en) * | 2020-12-15 | 2024-01-25 | Arizona Board Of Regents On Behalf Of Arizona State University | Antibodies specific for qsox1 and methods of using the same |
| CN112794900B (zh) * | 2020-12-31 | 2022-10-25 | 中南大学湘雅二医院 | cBIN1抗体及其应用 |
| CN112778414B (zh) * | 2020-12-31 | 2022-04-15 | 中南大学湘雅二医院 | cBIN1抗体及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6048702A (en) * | 1995-05-05 | 2000-04-11 | The Wistar Institute Of Anatomy And Biology | Murine and human box-dependent myc-interacting protein (Bin1) and uses therefor |
| CA2378982A1 (en) * | 1999-07-07 | 2001-01-18 | Regeneron Pharmaceuticals, Inc. | Methods of inhibiting muscle atrophy |
| US6831063B1 (en) * | 1999-08-31 | 2004-12-14 | The Wistar Institute Of Anatomy And Biology | Bridging Integrator-2(Bin2) nucleic acid molecules and proteins and uses therefor |
| WO2005037230A2 (en) * | 2003-10-14 | 2005-04-28 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for treating heart failure |
| CA2578680C (en) | 2004-04-15 | 2011-06-14 | University Of Florida Research Foundation, Inc. | Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining |
| WO2006009629A2 (en) * | 2004-06-10 | 2006-01-26 | New York University | Methods and agents for maintaining muscle mass and for preventing muscle atrophy and biomarkers for monitoring same |
| WO2008008846A2 (en) * | 2006-07-11 | 2008-01-17 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Differential expression of molecules associated with intra-cerebral hemorrhage |
| US20120094300A1 (en) * | 2009-04-24 | 2012-04-19 | Robin Shaw | Bin1 as a Prognostic Marker in Cardiovascular Disease |
| JP5890840B2 (ja) * | 2010-10-20 | 2016-03-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 心臓健康状態のマーカーとしての体液bin1 |
-
2011
- 2011-11-07 CA CA2817519A patent/CA2817519C/en active Active
- 2011-11-07 JP JP2013538809A patent/JP5866126B2/ja active Active
- 2011-11-07 EP EP11850406.7A patent/EP2638403B1/en active Active
- 2011-11-07 WO PCT/US2011/059574 patent/WO2012087437A2/en not_active Ceased
- 2011-11-07 AU AU2011345312A patent/AU2011345312A1/en not_active Abandoned
- 2011-11-07 US US13/884,454 patent/US9891232B2/en active Active
-
2017
- 2017-03-10 AU AU2017201661A patent/AU2017201661B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2817519C (en) | 2020-01-14 |
| EP2638403A4 (en) | 2014-05-07 |
| JP2014500960A (ja) | 2014-01-16 |
| WO2012087437A3 (en) | 2012-08-16 |
| EP2638403A2 (en) | 2013-09-18 |
| US20130324432A1 (en) | 2013-12-05 |
| WO2012087437A2 (en) | 2012-06-28 |
| AU2011345312A1 (en) | 2013-06-20 |
| AU2017201661B2 (en) | 2019-01-17 |
| US9891232B2 (en) | 2018-02-13 |
| EP2638403B1 (en) | 2017-03-22 |
| CA2817519A1 (en) | 2012-06-28 |
| AU2017201661A1 (en) | 2017-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5866126B2 (ja) | 骨格筋量および神経性状態のマーカーとしてのbin1発現 | |
| CN110720041B (zh) | 用心肌肌钙蛋白i和早期生物标记物帮助诊断和评价人受试者中轻度创伤性脑损伤的方法 | |
| JP7437303B2 (ja) | 外傷性脳損傷を診断及び査定するための、新規のバイオマーカー及び方法 | |
| KR20100135892A (ko) | 면역 관련 질병의 치료를 위한 신규한 조성물 및 방법 | |
| KR20200140400A (ko) | 집락 자극 인자 1 수용체(csf1r)에 결합하는 항체로 질환을 치료하는 방법 | |
| US10767227B2 (en) | Compositions and methods for determining genetic polymorphisms in the TMEM216 gene | |
| KR20050065575A (ko) | A33 항원 및 jam-it의 용도 | |
| US8906864B2 (en) | Binding domains of proteins of the repulsive guidance molecule (RGM) protein family and functional fragments thereof, and their use | |
| May et al. | Truncating variants in the SHANK1 gene are associated with a spectrum of neurodevelopmental disorders | |
| US20080107600A1 (en) | Gene Marker And Composition For Diagnosis And Treatment Of Neurological Disorders And Diseases And Use Of The Same | |
| JP2013039111A (ja) | スプライシングバリアント | |
| CN118715440A (zh) | 诊断脑损伤的方法和系统 | |
| EP2128272A1 (en) | Gene/protein marker for prediction or diagnosis of pharmacological efficacy of aurora a inhibitor | |
| US6680172B1 (en) | Treatments and markers for cancers of the central nervous system | |
| JP2018522947A (ja) | 非アルコール性脂肪肝調節因子14−3−3タンパク質 | |
| EP3133400B1 (en) | Use of ak6 and gpx5 male fertility related proteins or combination thereof | |
| US7776538B2 (en) | Method for diagnosing methamphetamine dependence | |
| CN110499365A (zh) | Agap9在制备诊断骨关节炎的产品中的应用 | |
| WO2026052672A1 (en) | Comp cleavage peptide and its use in diagnosis of osteoarthritis | |
| CA2532553A1 (en) | Methods for identifying compounds for regulating muscle mass or function using dopamine receptors | |
| KR101849685B1 (ko) | 샤르코-마리-투스병 제1형의 원인 유전자로서 pmp22 및 이를 이용한 상기 질병의 진단방법 | |
| US9638699B2 (en) | Biomarkers of oxidative stress | |
| KR20200112069A (ko) | 골 질환의 예방 또는 치료를 위한 Jmjd2b 억제제의 용도 | |
| HK1242740A1 (en) | Methods of prognosing, diagnosing and treating idiopathic pulmonary fibrosis | |
| JPWO2004016783A1 (ja) | アトピー性皮膚炎の検査方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20141106 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20141106 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20150729 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20150730 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20151023 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20151130 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20151230 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5866126 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |