CA2811086C - Step-derived peptide for brain injury treatment - Google Patents
Step-derived peptide for brain injury treatment Download PDFInfo
- Publication number
- CA2811086C CA2811086C CA2811086A CA2811086A CA2811086C CA 2811086 C CA2811086 C CA 2811086C CA 2811086 A CA2811086 A CA 2811086A CA 2811086 A CA2811086 A CA 2811086A CA 2811086 C CA2811086 C CA 2811086C
- Authority
- CA
- Canada
- Prior art keywords
- glu
- isolated peptide
- leu
- domain
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
- C12Y301/03048—Protein-tyrosine-phosphatase (3.1.3.48)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US38320810P | 2010-09-15 | 2010-09-15 | |
| US61/383,208 | 2010-09-15 | ||
| PCT/US2011/051827 WO2012037397A2 (en) | 2010-09-15 | 2011-09-15 | Step-derived peptide for brain injury treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2811086A1 CA2811086A1 (en) | 2012-03-22 |
| CA2811086C true CA2811086C (en) | 2020-07-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2811086A Expired - Fee Related CA2811086C (en) | 2010-09-15 | 2011-09-15 | Step-derived peptide for brain injury treatment |
Country Status (5)
| Country | Link |
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| US (3) | US9068172B2 (enExample) |
| EP (1) | EP2616485A4 (enExample) |
| JP (1) | JP6383151B2 (enExample) |
| CA (1) | CA2811086C (enExample) |
| WO (1) | WO2012037397A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2616485A4 (en) * | 2010-09-15 | 2014-04-02 | Stc Unm | STEPPED DEVELOPED PEPTIDE FOR THE TREATMENT OF BRAIN INJURIES |
| GB201314610D0 (en) | 2013-08-15 | 2013-10-02 | Blueberry Therapeutics Ltd | Compounds and their uses |
| WO2021155354A1 (en) * | 2020-01-31 | 2021-08-05 | Unm Rainforest Innovations | Regulation of post-ischemic inflammatory response |
| RO135590A1 (ro) | 2020-08-31 | 2022-03-30 | Szedlacsek Ştefan Eugen | Peptide de interferenţă ca inhibitori ai interacţiunilor legate de endocitoza receptorilor ampa |
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| US6015834A (en) | 1992-10-20 | 2000-01-18 | Toronto Neuroprotection Group | In vivo treatment of mammalian cells with a cell membrane permeant calcium buffer |
| CA2494348C (en) | 2002-08-01 | 2014-04-08 | Yeda Research And Development Co. Ltd. | Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels |
| US20050142630A1 (en) | 2003-12-08 | 2005-06-30 | Agy Therapeutics, Inc. | Interaction of NMDA receptor with the protein tyrosine phosphatase step in psychotic disorders |
| AU2007226134A1 (en) | 2006-03-16 | 2007-09-20 | Mor Research Applications Ltd. | Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels |
| US20090004112A1 (en) | 2006-04-21 | 2009-01-01 | The Trustees Of Columbia University In The City Of New York | Methods for the treatment of neurodegenerative diseases using nmda receptor glycine site antagonists |
| KR100999043B1 (ko) * | 2007-12-04 | 2010-12-09 | 한국생명공학연구원 | 융합 단백질을 사용하지 않는 인간 단백질 타이로신탈인산화 효소의 활성 도메인 대량 생산 방법 |
| WO2009099563A2 (en) | 2008-02-05 | 2009-08-13 | Blanchette Rockefeller Neurosciences Institute | Combination of a nmda receptor channel blocker and a pkc activator for treatment of alzheimer's disease |
| EP2616485A4 (en) * | 2010-09-15 | 2014-04-02 | Stc Unm | STEPPED DEVELOPED PEPTIDE FOR THE TREATMENT OF BRAIN INJURIES |
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2011
- 2011-09-15 EP EP11825972.0A patent/EP2616485A4/en not_active Withdrawn
- 2011-09-15 US US13/823,856 patent/US9068172B2/en active Active
- 2011-09-15 CA CA2811086A patent/CA2811086C/en not_active Expired - Fee Related
- 2011-09-15 JP JP2013529343A patent/JP6383151B2/ja not_active Expired - Fee Related
- 2011-09-15 WO PCT/US2011/051827 patent/WO2012037397A2/en not_active Ceased
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2015
- 2015-05-26 US US14/721,024 patent/US10087429B2/en active Active
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2018
- 2018-08-29 US US16/116,117 patent/US10570381B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012037397A3 (en) | 2012-06-28 |
| US20150252339A1 (en) | 2015-09-10 |
| JP2014505010A (ja) | 2014-02-27 |
| US10087429B2 (en) | 2018-10-02 |
| EP2616485A2 (en) | 2013-07-24 |
| WO2012037397A2 (en) | 2012-03-22 |
| US10570381B2 (en) | 2020-02-25 |
| CA2811086A1 (en) | 2012-03-22 |
| US9068172B2 (en) | 2015-06-30 |
| US20190169583A1 (en) | 2019-06-06 |
| EP2616485A4 (en) | 2014-04-02 |
| US20140170130A1 (en) | 2014-06-19 |
| JP6383151B2 (ja) | 2018-08-29 |
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