CA2804337A1 - Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis - Google Patents

Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis Download PDF

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Publication number
CA2804337A1
CA2804337A1 CA2804337A CA2804337A CA2804337A1 CA 2804337 A1 CA2804337 A1 CA 2804337A1 CA 2804337 A CA2804337 A CA 2804337A CA 2804337 A CA2804337 A CA 2804337A CA 2804337 A1 CA2804337 A1 CA 2804337A1
Authority
CA
Canada
Prior art keywords
pharmaceutical composition
ala
dry pharmaceutical
polymers
irradiation device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2804337A
Other languages
English (en)
French (fr)
Inventor
Bjorn Klem
Norbert Lange
Morten Groseth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Photocure ASA
Original Assignee
Photocure ASA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Photocure ASA filed Critical Photocure ASA
Publication of CA2804337A1 publication Critical patent/CA2804337A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/00615-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036Porphyrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2804337A 2010-07-09 2011-07-08 Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis Abandoned CA2804337A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10251232 2010-07-09
EP10251232.4 2010-07-09
PCT/EP2011/061688 WO2012004399A1 (en) 2010-07-09 2011-07-08 Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis

Publications (1)

Publication Number Publication Date
CA2804337A1 true CA2804337A1 (en) 2012-01-12

Family

ID=44628087

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2804337A Abandoned CA2804337A1 (en) 2010-07-09 2011-07-08 Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis

Country Status (9)

Country Link
US (1) US20130178787A1 (cg-RX-API-DMAC7.html)
EP (1) EP2590714B1 (cg-RX-API-DMAC7.html)
JP (1) JP5991970B2 (cg-RX-API-DMAC7.html)
KR (1) KR101842732B1 (cg-RX-API-DMAC7.html)
AU (1) AU2011275695B2 (cg-RX-API-DMAC7.html)
BR (1) BR112013000613A2 (cg-RX-API-DMAC7.html)
CA (1) CA2804337A1 (cg-RX-API-DMAC7.html)
ES (1) ES2620780T3 (cg-RX-API-DMAC7.html)
WO (1) WO2012004399A1 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013053927A1 (en) 2011-10-14 2013-04-18 Photocure Asa Photodynamic diagnosis of abnormalities of the epithelial lining of the oesophagus with the means of a 5-ala ester
CN102670577B (zh) * 2012-05-18 2018-04-13 上海复旦张江生物医药股份有限公司 一种光敏剂组合物、其使用方法及用途
US20140067024A1 (en) 2012-08-30 2014-03-06 Photocure Asa Dual panel photodynamic therapy lamp
GB201221123D0 (en) 2012-11-23 2013-01-09 Photocure As Device for photodynamic treatment
GB201306369D0 (en) 2013-04-09 2013-05-22 Photocure As Irradiation device
CN105683752B (zh) * 2013-06-21 2019-03-29 国立大学法人冈山大学 基于异常活化细胞检测的恶性肿瘤的检查方法及去除异常活化细胞血液循环回输治疗装置
GB201522398D0 (en) 2015-12-18 2016-02-03 Photocure As Device for photodynamic therapy
ES2965514T3 (es) * 2017-06-21 2024-04-15 Photocure Asa Procedimiento de preparación de una composición farmacéutica líquida y dispositivo para su uso en dicho procedimiento
US20250188521A1 (en) * 2022-03-10 2025-06-12 Singular Genomics Systems, Inc. Nucleic acid delivery scaffolds

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996023543A1 (en) * 1995-01-30 1996-08-08 Angiomedics Ii Incorporated Photolytic drug delivery systems
CA2215069C (en) 1995-03-10 2006-09-12 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB2370992B (en) * 2000-03-23 2002-11-20 Photo Therapeutics Ltd Therapeutic light source and method
US6551346B2 (en) * 2000-05-17 2003-04-22 Kent Crossley Method and apparatus to prevent infections
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
GB0018527D0 (en) 2000-07-27 2000-09-13 Photocure Asa Composition
GB0118251D0 (en) 2001-07-26 2001-09-19 Photocure Asa Method
PL368612A1 (en) * 2001-08-14 2005-04-04 Biotie Therapies Corporation Method of treating alcoholism or alcohol abuse
EP1312353A1 (en) 2001-11-16 2003-05-21 Ecole Polytechnique Federale De Lausanne (Epfl) Method for hair removal
DE10202487A1 (de) * 2002-01-23 2003-07-31 Photonamic Gmbh & Co Kg Dermales Applikationssystem für Aminolävulinsäure-Derivate
US20050085455A1 (en) * 2003-10-16 2005-04-21 Light Sciences Corporation Photodynamic therapy for local adipocyte reduction
CA2457214A1 (en) * 2004-02-06 2005-08-06 Qlt Inc. Photodynamic therapy for the treatment of acne
GB0406917D0 (en) 2004-03-26 2004-04-28 Photocure Asa Compounds
GB0424833D0 (en) 2004-11-10 2004-12-15 Photocure Asa Method
CN101107043A (zh) * 2005-01-18 2008-01-16 皇家飞利浦电子股份有限公司 用于释放辐射的电控胶囊
US20090319008A1 (en) * 2005-03-31 2009-12-24 Esther Mayer Probe device, system and method for photobiomodulation of tissue lining a body cavity
US20070260231A1 (en) * 2005-04-21 2007-11-08 Ondine International, Ltd. Optical probe for delivery of light
DE102006001736A1 (de) * 2006-01-13 2007-07-26 Margull, Matthias, Dipl.-Ing. Vorrichtung zur Applikation von monochromatischem Licht in Körperöffnungen
GB0608315D0 (en) * 2006-04-27 2006-06-07 Univ St Andrews Light emitting device for use in therapeutic and/or cosmetic treatment
US8292935B2 (en) * 2006-09-12 2012-10-23 Bistitec Pharma Marketing Ltd Photonic device and method for treating cervical dysplasia
GB0724279D0 (en) * 2007-12-12 2008-01-23 Photocure Asa Use
GB0816027D0 (en) * 2008-09-03 2008-10-08 Lumicure Ltd Controlled light emitting apparatus
GB0823472D0 (en) * 2008-12-23 2009-01-28 Photocure Asa Product
GB0900461D0 (en) 2009-01-12 2009-02-11 Photocure Asa Photodynamic therapy device
EP2440199B1 (en) 2009-06-11 2016-04-13 Photocure ASA Semi-solid compositions and pharmaceutical products

Also Published As

Publication number Publication date
US20130178787A1 (en) 2013-07-11
WO2012004399A1 (en) 2012-01-12
BR112013000613A2 (pt) 2016-06-28
JP2013532035A (ja) 2013-08-15
KR20130083436A (ko) 2013-07-22
EP2590714B1 (en) 2017-03-08
AU2011275695A1 (en) 2013-02-14
EP2590714A1 (en) 2013-05-15
AU2011275695B2 (en) 2014-07-31
ES2620780T3 (es) 2017-06-29
KR101842732B1 (ko) 2018-05-14
CN103118742A (zh) 2013-05-22
JP5991970B2 (ja) 2016-09-14

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20160620

FZDE Discontinued

Effective date: 20190709