CA2796438A1 - Method for purifying bio-organic compounds from fermentation broth containing surfactants by temperature-induced phase inversion - Google Patents
Method for purifying bio-organic compounds from fermentation broth containing surfactants by temperature-induced phase inversion Download PDFInfo
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- CA2796438A1 CA2796438A1 CA2796438A CA2796438A CA2796438A1 CA 2796438 A1 CA2796438 A1 CA 2796438A1 CA 2796438 A CA2796438 A CA 2796438A CA 2796438 A CA2796438 A CA 2796438A CA 2796438 A1 CA2796438 A1 CA 2796438A1
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- Prior art keywords
- composition
- emulsion
- bio
- oil
- temperature
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- 239000001257 hydrogen Substances 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000005511 kinetic theory Methods 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 1
- 239000000347 magnesium hydroxide Substances 0.000 description 1
- 229910001862 magnesium hydroxide Inorganic materials 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- VOVZXURTCKPRDQ-CQSZACIVSA-N n-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3r)-3-hydroxypyrrolidin-1-yl]-5-(1h-pyrazol-5-yl)pyridine-3-carboxamide Chemical compound C1[C@H](O)CCN1C1=NC=C(C(=O)NC=2C=CC(OC(F)(F)Cl)=CC=2)C=C1C1=CC=NN1 VOVZXURTCKPRDQ-CQSZACIVSA-N 0.000 description 1
- WASNIKZYIWZQIP-AWEZNQCLSA-N nerolidol Natural products CC(=CCCC(=CCC[C@@H](O)C=C)C)C WASNIKZYIWZQIP-AWEZNQCLSA-N 0.000 description 1
- GSGDTSDELPUTKU-UHFFFAOYSA-N nonoxybenzene Chemical compound CCCCCCCCCOC1=CC=CC=C1 GSGDTSDELPUTKU-UHFFFAOYSA-N 0.000 description 1
- 150000007823 ocimene derivatives Chemical class 0.000 description 1
- 229920002114 octoxynol-9 Polymers 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid group Chemical group C(CCCCCCC\C=C/CCCCCCCC)(=O)O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920000259 polyoxyethylene lauryl ether Polymers 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000002731 protein assay Methods 0.000 description 1
- 229930006696 sabinene Natural products 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000007655 standard test method Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- UUCCCPNEFXQJEL-UHFFFAOYSA-L strontium dihydroxide Chemical compound [OH-].[OH-].[Sr+2] UUCCCPNEFXQJEL-UHFFFAOYSA-L 0.000 description 1
- 229910001866 strontium hydroxide Inorganic materials 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 229930006978 terpinene Natural products 0.000 description 1
- 150000003507 terpinene derivatives Chemical class 0.000 description 1
- 238000000954 titration curve Methods 0.000 description 1
- CRDAMVZIKSXKFV-UHFFFAOYSA-N trans-Farnesol Natural products CC(C)=CCCC(C)=CCCC(C)=CCO CRDAMVZIKSXKFV-UHFFFAOYSA-N 0.000 description 1
- XJPBRODHZKDRCB-UHFFFAOYSA-N trans-alpha-ocimene Natural products CC(=C)CCC=C(C)C=C XJPBRODHZKDRCB-UHFFFAOYSA-N 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000010977 unit operation Methods 0.000 description 1
- WCTNXGFHEZQHDR-UHFFFAOYSA-N valencene Natural products C1CC(C)(C)C2(C)CC(C(=C)C)CCC2=C1 WCTNXGFHEZQHDR-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C7/00—Purification; Separation; Use of additives
- C07C7/11—Purification; Separation; Use of additives by absorption, i.e. purification or separation of gaseous hydrocarbons with the aid of liquids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C7/00—Purification; Separation; Use of additives
- C07C7/10—Purification; Separation; Use of additives by extraction, i.e. purification or separation of liquid hydrocarbons with the aid of liquids
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Analytical Chemistry (AREA)
- Water Supply & Treatment (AREA)
- Colloid Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37387610P | 2010-08-16 | 2010-08-16 | |
| US61/373,876 | 2010-08-16 | ||
| PCT/US2011/047616 WO2012024186A1 (en) | 2010-08-16 | 2011-08-12 | Method for purifying bio-organic compounds from fermentation broth containing surfactants by temperature-induced phase inversion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2796438A1 true CA2796438A1 (en) | 2012-02-23 |
Family
ID=44515045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2796438A Abandoned CA2796438A1 (en) | 2010-08-16 | 2011-08-12 | Method for purifying bio-organic compounds from fermentation broth containing surfactants by temperature-induced phase inversion |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20120040396A1 (https=) |
| EP (1) | EP2606018A1 (https=) |
| JP (1) | JP2013534144A (https=) |
| KR (1) | KR20130108064A (https=) |
| CN (1) | CN103052612A (https=) |
| AU (1) | AU2011292231B2 (https=) |
| BR (1) | BR112012027462A2 (https=) |
| CA (1) | CA2796438A1 (https=) |
| MX (1) | MX2012012705A (https=) |
| WO (1) | WO2012024186A1 (https=) |
| ZA (1) | ZA201207717B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2866553A1 (en) * | 2012-03-07 | 2013-09-12 | Abengoa Bioenergy New Technologies, Llc | Methods for enhancing the recovery of oil during biofuel production |
| EP3110930B1 (en) | 2014-02-28 | 2020-04-15 | Delft Advanced Biofuels B.V. | Process for the recovery of lipids or hydrocarbons |
| US11103808B2 (en) | 2017-08-07 | 2021-08-31 | Amyris, Inc. | Process for recovering isoprenoids produced by microorganisms |
| JP7504031B2 (ja) * | 2018-06-29 | 2024-06-21 | アミリス， インコーポレイテッド | 微生物バイオマスから不水溶性イソプレノイド化合物を回収するための方法 |
| EP3766982A1 (en) | 2019-07-18 | 2021-01-20 | Delft Advanced Biofuels B.V. | Integrated system for biocatalytically producing and recovering an organic substance |
| EP4646426A1 (en) | 2023-01-03 | 2025-11-12 | Amyris, Inc. | Host cells capable of producing sequiterpenoids and methods of use thereof |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2427326A (en) * | 1945-02-13 | 1947-09-09 | Socony Vacuum Oil Co Inc | Treatment of mineral oil emulsions |
| US2782244A (en) * | 1952-01-24 | 1957-02-19 | Phillips Petroleum Co | Isomerizing hydrocarbons with the catalyst in the continuous phase inverting the phases and separating the catalyst employing phase inversion |
| US4725287A (en) * | 1986-11-24 | 1988-02-16 | Canadian Occidental Petroleum, Ltd. | Preparation of stable crude oil transport emulsions |
| US5730905A (en) * | 1994-06-21 | 1998-03-24 | Betzdearborn Inc. | Method of resolving oil and water emulsions |
| US6431370B1 (en) * | 1995-01-27 | 2002-08-13 | Genencor International, Inc. | Direct enzyme agglomeration process |
| NZ514891A (en) * | 1999-03-25 | 2003-10-31 | Valtion Teknillinen | Process for partitioning of proteins using hydrophobin proteins fused to the cell or protein of choice |
| DE10035930A1 (de) * | 2000-07-21 | 2002-01-31 | Clariant Gmbh | Feinemulsionen |
| US7179311B2 (en) * | 2003-01-31 | 2007-02-20 | Chevron U.S.A. Inc. | Stable olefinic, low sulfur diesel fuels |
| CN1246451C (zh) * | 2003-08-07 | 2006-03-22 | 上海来益生物药物研究开发中心有限责任公司 | 浊点系统在生物转化中的应用 |
| CA2652801C (en) | 2006-05-26 | 2018-05-22 | Amyris Biotechnologies, Inc. | Apparatus for making bio-organic compounds |
| WO2007140339A2 (en) | 2006-05-26 | 2007-12-06 | Amyris Biotechnologies, Inc. | Production of isoprenoids |
| BRPI0713105B8 (pt) * | 2006-05-26 | 2021-05-25 | Amyris Biotechnologies Inc | método para produzir um isoprenóide |
| US7399323B2 (en) * | 2006-10-10 | 2008-07-15 | Amyris Biotechnologies, Inc. | Fuel compositions comprising farnesane and farnesane derivatives and method of making and using same |
| WO2008133658A2 (en) | 2006-11-21 | 2008-11-06 | Amyris Biotechnologies, Inc. | Jet fuel compositions and methods of making and using same |
| US7942940B2 (en) | 2006-11-21 | 2011-05-17 | Amyris Biotechnologies, Inc. | Jet fuel compositions and methods of making and using same |
| CN101260137B (zh) * | 2007-03-07 | 2010-12-08 | 中国科学院过程工程研究所 | 用微波辅助浊点萃取从甘草中提纯并精制甘草酸的方法 |
| US8110093B2 (en) | 2007-03-14 | 2012-02-07 | Ls9, Inc. | Process for producing low molecular weight hydrocarbons from renewable resources |
| US20090004715A1 (en) | 2007-06-01 | 2009-01-01 | Solazyme, Inc. | Glycerol Feedstock Utilization for Oil-Based Fuel Manufacturing |
| CA2694982C (en) | 2007-07-20 | 2013-06-25 | Amyris Biotechnologies, Inc. | Fuel compositions comprising tetramethylcyclohexane |
| EP2288675B1 (en) | 2008-05-02 | 2013-06-12 | Amyris, Inc. | Fuel compositions comprising an amorphane or a stereoisomer thereof and methods of making and using same |
| US7655739B1 (en) | 2009-06-26 | 2010-02-02 | Amyris Biotechnologies, Inc. | Adhesive compositions comprising a polyfarnesene |
| US7589243B1 (en) | 2008-09-17 | 2009-09-15 | Amyris Biotechnologies, Inc. | Jet fuel compositions |
| US7592295B1 (en) | 2008-10-10 | 2009-09-22 | Amyris Biotechnologies, Inc. | Farnesene dimers and/or farnesane dimers and compositions thereof |
-
2011
- 2011-08-05 US US13/198,711 patent/US20120040396A1/en not_active Abandoned
- 2011-08-12 BR BR112012027462A patent/BR112012027462A2/pt not_active IP Right Cessation
- 2011-08-12 AU AU2011292231A patent/AU2011292231B2/en not_active Ceased
- 2011-08-12 JP JP2013524893A patent/JP2013534144A/ja active Pending
- 2011-08-12 EP EP11749297.5A patent/EP2606018A1/en not_active Withdrawn
- 2011-08-12 MX MX2012012705A patent/MX2012012705A/es not_active Application Discontinuation
- 2011-08-12 CA CA2796438A patent/CA2796438A1/en not_active Abandoned
- 2011-08-12 KR KR1020127028294A patent/KR20130108064A/ko not_active Withdrawn
- 2011-08-12 ZA ZA201207717A patent/ZA201207717B/xx unknown
- 2011-08-12 CN CN2011800374729A patent/CN103052612A/zh active Pending
- 2011-08-12 WO PCT/US2011/047616 patent/WO2012024186A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012024186A1 (en) | 2012-02-23 |
| AU2011292231B2 (en) | 2013-11-21 |
| US20120040396A1 (en) | 2012-02-16 |
| AU2011292231A1 (en) | 2012-12-13 |
| JP2013534144A (ja) | 2013-09-02 |
| ZA201207717B (en) | 2013-12-23 |
| BR112012027462A2 (pt) | 2016-07-19 |
| EP2606018A1 (en) | 2013-06-26 |
| KR20130108064A (ko) | 2013-10-02 |
| CN103052612A (zh) | 2013-04-17 |
| MX2012012705A (es) | 2012-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20160812 |