CA2795438A1 - Method of detecting and profiling progression of the risk of neurodegenerative diseases - Google Patents

Method of detecting and profiling progression of the risk of neurodegenerative diseases Download PDF

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Publication number
CA2795438A1
CA2795438A1 CA2795438A CA2795438A CA2795438A1 CA 2795438 A1 CA2795438 A1 CA 2795438A1 CA 2795438 A CA2795438 A CA 2795438A CA 2795438 A CA2795438 A CA 2795438A CA 2795438 A1 CA2795438 A1 CA 2795438A1
Authority
CA
Canada
Prior art keywords
stem cell
determining
antibody
subject
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2795438A
Other languages
English (en)
French (fr)
Inventor
C. Shekhar Mayanil
Shunsuke Ichi
Tadanori Tomita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ann and Robert H Lurie Childrens Hospital of Chicago
Original Assignee
Ann and Robert H Lurie Childrens Hospital of Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ann and Robert H Lurie Childrens Hospital of Chicago filed Critical Ann and Robert H Lurie Childrens Hospital of Chicago
Publication of CA2795438A1 publication Critical patent/CA2795438A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/12Post-translational modifications [PTMs] in chemical analysis of biological material alkylation, e.g. methylation, (iso-)prenylation, farnesylation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2835Movement disorders, e.g. Parkinson, Huntington, Tourette
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
CA2795438A 2010-05-11 2011-04-21 Method of detecting and profiling progression of the risk of neurodegenerative diseases Abandoned CA2795438A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39532110P 2010-05-11 2010-05-11
US61/395,321 2010-05-11
PCT/US2011/033387 WO2011142952A1 (en) 2010-05-11 2011-04-21 Method of detecting and profiling progression of the risk of neurodegenerative diseases

Publications (1)

Publication Number Publication Date
CA2795438A1 true CA2795438A1 (en) 2011-11-17

Family

ID=44914644

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2795438A Abandoned CA2795438A1 (en) 2010-05-11 2011-04-21 Method of detecting and profiling progression of the risk of neurodegenerative diseases

Country Status (5)

Country Link
US (1) US20130029998A1 (cg-RX-API-DMAC7.html)
EP (1) EP2569625A4 (cg-RX-API-DMAC7.html)
JP (1) JP2013526705A (cg-RX-API-DMAC7.html)
CA (1) CA2795438A1 (cg-RX-API-DMAC7.html)
WO (1) WO2011142952A1 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016196765A2 (en) 2015-06-03 2016-12-08 Aelan Cell Technologies, Inc. Companion methods and kits for il-2-based therapies and mesenchymal stem cell-based therapies
US10282875B2 (en) 2015-12-11 2019-05-07 International Business Machines Corporation Graph-based analysis for bio-signal event sensing
WO2017184873A2 (en) * 2016-04-20 2017-10-26 Aelan Cell Technologies, Inc. Compositions and methods related to the methylation of histone h1.0 protein
KR102573778B1 (ko) 2017-02-17 2023-08-31 브리스톨-마이어스 스큅 컴퍼니 알파-시뉴클레인에 대한 항체 및 그의 용도
CN118772271A (zh) * 2017-10-25 2024-10-15 爱兰细胞技术公司 H1.0k180me2抗体、其制造方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11016A (en) * 1854-06-06 Method of turning hubs
US7025A (en) * 1850-01-15 Buckle
US20050037992A1 (en) * 2003-07-22 2005-02-17 John Lyons Composition and method for treating neurological disorders
CN101909630A (zh) * 2007-11-02 2010-12-08 新加坡科技研究局 预防和治疗肿瘤的方法和化合物
WO2010001933A1 (ja) * 2008-07-01 2010-01-07 学校法人日本大学 標的遺伝子特異的ヒストン修飾制御剤

Also Published As

Publication number Publication date
WO2011142952A1 (en) 2011-11-17
JP2013526705A (ja) 2013-06-24
EP2569625A4 (en) 2013-12-04
US20130029998A1 (en) 2013-01-31
EP2569625A1 (en) 2013-03-20

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead

Effective date: 20160421